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Items: 1 to 20 of 120

1.

Age and gender effects of 11C-ITMM binding to metabotropic glutamate receptor type 1 in healthy human participants.

Sakata M, Toyohara J, Ishibashi K, Wagatsuma K, Ishii K, Zhang MR, Ishiwata K.

Neurobiol Aging. 2017 Jul;55:72-77. doi: 10.1016/j.neurobiolaging.2017.03.022. Epub 2017 Mar 28.

PMID:
28431287
2.

Are Type 1 metabotropic glutamate receptors a viable therapeutic target for the treatment of cerebellar ataxia?

Power EM, English NA, Empson RM.

J Physiol. 2016 Aug 15;594(16):4643-52. doi: 10.1113/JP271153. Epub 2016 Feb 24. Review.

3.

Atypical signaling of metabotropic glutamate receptor 1 in human melanoma cells.

Gelb T, Pshenichkin S, Hathaway HA, Grajkowska E, Dalley CB, Wolfe BB, Wroblewski JT.

Biochem Pharmacol. 2015 Nov 1;98(1):182-9. doi: 10.1016/j.bcp.2015.08.091. Epub 2015 Aug 17.

PMID:
26291396
4.

Metabotropic glutamate receptor 1 disrupts mammary acinar architecture and initiates malignant transformation of mammary epithelial cells.

Teh JL, Shah R, La Cava S, Dolfi SC, Mehta MS, Kongara S, Price S, Ganesan S, Reuhl KR, Hirshfield KM, Karantza V, Chen S.

Breast Cancer Res Treat. 2015 May;151(1):57-73. doi: 10.1007/s10549-015-3365-8. Epub 2015 Apr 10.

5.

Chemical modulation of mutant mGlu1 receptors derived from deleterious GRM1 mutations found in schizophrenics.

Cho HP, Garcia-Barrantes PM, Brogan JT, Hopkins CR, Niswender CM, Rodriguez AL, Venable DF, Morrison RD, Bubser M, Daniels JS, Jones CK, Conn PJ, Lindsley CW.

ACS Chem Biol. 2014 Oct 17;9(10):2334-46. doi: 10.1021/cb500560h. Epub 2014 Aug 28.

6.

Identification of novel GRM1 mutations and single nucleotide polymorphisms in prostate cancer cell lines and tissues.

Ali S, Shourideh M, Koochekpour S.

PLoS One. 2014 Jul 25;9(7):e103204. doi: 10.1371/journal.pone.0103204. eCollection 2014.

7.

GRM1 is upregulated through gene fusion and promoter swapping in chondromyxoid fibroma.

Nord KH, Lilljebjörn H, Vezzi F, Nilsson J, Magnusson L, Tayebwa J, de Jong D, Bovée JV, Hogendoorn PC, Szuhai K.

Nat Genet. 2014 May;46(5):474-7. doi: 10.1038/ng.2927. Epub 2014 Mar 23.

PMID:
24658000
8.

Activation of the glutamate receptor GRM1 enhances angiogenic signaling to drive melanoma progression.

Wen Y, Li J, Koo J, Shin SS, Lin Y, Jeong BS, Mehnert JM, Chen S, Cohen-Sola KA, Goydos JS.

Cancer Res. 2014 May 1;74(9):2499-509. doi: 10.1158/0008-5472.CAN-13-1531. Epub 2014 Feb 3.

9.

Metabotropic glutamate receptor-1 contributes to progression in triple negative breast cancer.

Banda M, Speyer CL, Semma SN, Osuala KO, Kounalakis N, Torres Torres KE, Barnard NJ, Kim HJ, Sloane BF, Miller FR, Goydos JS, Gorski DH.

PLoS One. 2014 Jan 3;9(1):e81126. doi: 10.1371/journal.pone.0081126. eCollection 2014.

10.

[Pharmacological characterization of metabotropic glutamate-receptor 1 antagonist for the treatment of schizophrenia].

Maehara S.

Nihon Yakurigaku Zasshi. 2013 Dec;142(6):280-4. Review. Japanese. No abstract available.

PMID:
24334926
11.

Extracellular calcium modulates actions of orthosteric and allosteric ligands on metabotropic glutamate receptor 1α.

Jiang JY, Nagaraju M, Meyer RC, Zhang L, Hamelberg D, Hall RA, Brown EM, Conn PJ, Yang JJ.

J Biol Chem. 2014 Jan 17;289(3):1649-61. doi: 10.1074/jbc.M113.507665. Epub 2013 Nov 26.

12.

Metabotropic glutamate receptor 1 expression and its polymorphic variants associate with breast cancer phenotypes.

Mehta MS, Dolfi SC, Bronfenbrener R, Bilal E, Chen C, Moore D, Lin Y, Rahim H, Aisner S, Kersellius RD, Teh J, Chen S, Toppmeyer DL, Medina DJ, Ganesan S, Vazquez A, Hirshfield KM.

PLoS One. 2013 Jul 26;8(7):e69851. doi: 10.1371/journal.pone.0069851. Print 2013.

13.

Human synaptic plasticity gene expression profile and dendritic spine density changes in HIV-infected human CNS cells: role in HIV-associated neurocognitive disorders (HAND).

Atluri VS, Kanthikeel SP, Reddy PV, Yndart A, Nair MP.

PLoS One. 2013 Apr 19;8(4):e61399. doi: 10.1371/journal.pone.0061399. Print 2013.

14.

Two newly identified exons in human GRM1 express a novel splice variant of metabotropic glutamate 1 receptor.

DiRaddo JO, Pshenichkin S, Gelb T, Wroblewski JT.

Gene. 2013 May 1;519(2):367-73. doi: 10.1016/j.gene.2013.02.009. Epub 2013 Feb 24.

15.

Somatic mutations in GRM1 in cancer alter metabotropic glutamate receptor 1 intracellular localization and signaling.

Esseltine JL, Willard MD, Wulur IH, Lajiness ME, Barber TD, Ferguson SS.

Mol Pharmacol. 2013 Apr;83(4):770-80. doi: 10.1124/mol.112.081695. Epub 2013 Jan 9.

16.

A sequential impairment of cortical astrocytes and GABAergic neurons during ischemia is improved by mGluR₁,₅ activation.

Liu Z, Huo W, Sun W, Lv M, Li F, Su Z.

Neurol Sci. 2013 Jul;34(7):1189-95. doi: 10.1007/s10072-012-1220-9. Epub 2012 Oct 31.

PMID:
23109136
17.

Metabotropic glutamate receptor 1 (Grm1) is an oncogene in epithelial cells.

Martino JJ, Wall BA, Mastrantoni E, Wilimczyk BJ, La Cava SN, Degenhardt K, White E, Chen S.

Oncogene. 2013 Sep 12;32(37):4366-76. doi: 10.1038/onc.2012.471. Epub 2012 Oct 22.

18.

Autosomal-recessive congenital cerebellar ataxia is caused by mutations in metabotropic glutamate receptor 1.

Guergueltcheva V, Azmanov DN, Angelicheva D, Smith KR, Chamova T, Florez L, Bynevelt M, Nguyen T, Cherninkova S, Bojinova V, Kaprelyan A, Angelova L, Morar B, Chandler D, Kaneva R, Bahlo M, Tournev I, Kalaydjieva L.

Am J Hum Genet. 2012 Sep 7;91(3):553-64. doi: 10.1016/j.ajhg.2012.07.019. Epub 2012 Aug 16.

19.

Sequential inter- and intrasubunit rearrangements during activation of dimeric metabotropic glutamate receptor 1.

Hlavackova V, Zabel U, Frankova D, Bätz J, Hoffmann C, Prezeau L, Pin JP, Blahos J, Lohse MJ.

Sci Signal. 2012 Aug 14;5(237):ra59. doi: 10.1126/scisignal.2002720.

20.

Functional effects of GRM1 suppression in human melanoma cells.

Wangari-Talbot J, Wall BA, Goydos JS, Chen S.

Mol Cancer Res. 2012 Nov;10(11):1440-50. doi: 10.1158/1541-7786.MCR-12-0158. Epub 2012 Jul 13.

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