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Items: 1 to 20 of 201

1.

Gene-gene interactions lead to higher risk for development of type 2 diabetes in a Chinese Han population: a prospective nested case-control study.

Zhou W, Li Y, Zhang L, Shi Y, Wang C, Zhang D, Liu X, Mao Z, Li L.

Lipids Health Dis. 2018 Jul 28;17(1):179. doi: 10.1186/s12944-018-0813-6.

2.

A case-control study and meta-analysis confirm glucokinase regulatory gene rs780094 is a risk factor for gestational diabetes mellitus.

Jamalpour S, Zain SM, Mosavat M, Mohamed Z, Omar SZ.

Gene. 2018 Apr 15;650:34-40. doi: 10.1016/j.gene.2018.01.091. Epub 2018 Jan 31.

PMID:
29410004
3.

Identification and characterization of a FOXA2-regulated transcriptional enhancer at a type 2 diabetes intronic locus that controls GCKR expression in liver cells.

López Rodríguez M, Kaminska D, Lappalainen K, Pihlajamäki J, Kaikkonen MU, Laakso M.

Genome Med. 2017 Jul 6;9(1):63. doi: 10.1186/s13073-017-0453-x.

4.

An Exome-Chip Association Analysis in Chinese Subjects Reveals a Functional Missense Variant of GCKR That Regulates FGF21 Levels.

Cheung CYY, Tang CS, Xu A, Lee CH, Au KW, Xu L, Fong CHY, Kwok KHM, Chow WS, Woo YC, Yuen MMA, Cherny SS, Hai J, Cheung BMY, Tan KCB, Lam TH, Tse HF, Sham PC, Lam KSL.

Diabetes. 2017 Jun;66(6):1723-1728. doi: 10.2337/db16-1384. Epub 2017 Apr 6.

5.

A Common Gene Variant in Glucokinase Regulatory Protein Interacts With Glucose Metabolism on Diabetic Dyslipidemia: the Combined CODAM and Hoorn Studies.

Simons N, Dekker JM, van Greevenbroek MM, Nijpels G, 't Hart LM, van der Kallen CJ, Schalkwijk CG, Schaper NC, Stehouwer CD, Brouwers MC.

Diabetes Care. 2016 Oct;39(10):1811-7. doi: 10.2337/dc16-0153.

PMID:
27660121
6.

The GCKR Gene Polymorphism rs780094 is a Risk Factor for Gestational Diabetes in a Brazilian Population.

Anghebem-Oliveira MI, Webber S, Alberton D, de Souza EM, Klassen G, Picheth G, Rego FG.

J Clin Lab Anal. 2017 Mar;31(2). doi: 10.1002/jcla.22035. Epub 2016 Aug 24.

PMID:
27554451
7.

[Association of GCKR gene polymorphisms and type 2 diabetes among ethnic Uygurs].

Ma Q, Wang L, Yao H, Zhu J, Wang S, Zhang X, Wang T, Ma Y, Su Y, Wang Z, Ding L.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2016 Aug;33(4):540-4. doi: 10.3760/cma.j.issn.1003-9406.2016.04.026. Chinese.

PMID:
27455017
8.

Association Between a Glucokinase Regulator Genetic Variant and Metabolic Syndrome in Taiwanese Adolescents.

Chang HW, Lin FH, Li PF, Huang CL, Chu NF, Su SC, Lu CH, Lee CH, Hung YJ, Hsieh CH.

Genet Test Mol Biomarkers. 2016 Mar;20(3):137-42. doi: 10.1089/gtmb.2015.0241. Epub 2016 Jan 22.

PMID:
26799416
9.

Lifestyle Intervention for Weight Loss and Cardiometabolic Changes in the Setting of Glucokinase Regulatory Protein Inhibition: Glucokinase Regulatory Protein-Leu446Pro Variant in Look AHEAD.

Belalcazar LM, Papandonatos GD, Erar B, Peter I, Alkofide H, Balasubramanyam A, Brautbar A, Kahn SE, Knowler WC, Ballantyne CM, McCaffery JM, Huggins GS; Genetics Subgroup of the Look AHEAD Study*.

Circ Cardiovasc Genet. 2016 Feb;9(1):71-8. doi: 10.1161/CIRCGENETICS.115.001192. Epub 2015 Nov 17.

10.

Discrete associations of the GCKR variant with metabolic risk in a Chinese population: longitudinal change analysis.

Xu M, Lv X, Xie L, Huang X, Huang Y, Chen Y, Peng K, Wang P, Wang W, Qi L, Bi Y, Sun Y, Ning G.

Diabetologia. 2016 Feb;59(2):307-15. doi: 10.1007/s00125-015-3788-0. Epub 2015 Oct 29.

PMID:
26515422
11.

Modulation of Glucokinase Regulatory Protein: A Double-Edged Sword?

Brouwers MCGJ, Jacobs C, Bast A, Stehouwer CDA, Schaper NC.

Trends Mol Med. 2015 Oct;21(10):583-594. doi: 10.1016/j.molmed.2015.08.004. Review.

PMID:
26432016
12.

The dietary monounsaturated to saturated fatty acid ratio modulates the genetic effects of GCKR on serum lipid levels in children.

Lee HJ, Jang HB, Kim HJ, Ahn Y, Hong KW, Cho SB, Kang JH, Park SI.

Clin Chim Acta. 2015 Oct 23;450:155-61. doi: 10.1016/j.cca.2015.08.012. Epub 2015 Aug 18.

PMID:
26291577
13.

The n-3 long-chain PUFAs modulate the impact of the GCKR Pro446Leu polymorphism on triglycerides in adolescents.

Rousseaux J, Duhamel A, Dumont J, Dallongeville J, Molnar D, Widhalm K, Manios Y, Sjöström M, Kafatos A, Breidenassel C, Gonzales-Gross M, Cuenca-Garcia M, Censi L, Ascensión M, De Henauw S, Moreno LA, Meirhaeghe A, Gottrand F.

J Lipid Res. 2015 Sep;56(9):1774-80. doi: 10.1194/jlr.M057570. Epub 2015 Jul 1.

14.

Hepatic De Novo Lipogenesis in Obese Youth Is Modulated by a Common Variant in the GCKR Gene.

Santoro N, Caprio S, Pierpont B, Van Name M, Savoye M, Parks EJ.

J Clin Endocrinol Metab. 2015 Aug;100(8):E1125-32. doi: 10.1210/jc.2015-1587. Epub 2015 Jun 4.

15.

GCKR polymorphism influences liver fat content in patients with type 2 diabetes.

Petit JM, Masson D, Guiu B, Rollot F, Duvillard L, Bouillet B, Brindisi MC, Buffier P, Hillon P, Cercueil JP, Verges B.

Acta Diabetol. 2016 Apr;53(2):237-42. doi: 10.1007/s00592-015-0766-4. Epub 2015 May 16.

PMID:
25976242
16.

Glucokinase regulatory protein: complexity at the crossroads of triglyceride and glucose metabolism.

Raimondo A, Rees MG, Gloyn AL.

Curr Opin Lipidol. 2015 Apr;26(2):88-95. doi: 10.1097/MOL.0000000000000155. Review.

17.

Association between maternal single nucleotide polymorphisms in genes regulating glucose metabolism and risk for neural tube defects in offspring.

Fu Y, Wang LL, Yi D, Jin L, Liu J, Zhang Y, Ren A.

Birth Defects Res A Clin Mol Teratol. 2015 Jun;103(6):471-8. doi: 10.1002/bdra.23332. Epub 2014 Nov 5.

PMID:
25369983
18.

Common variant in the glucokinase regulatory gene rs780094 and risk of nonalcoholic fatty liver disease: a meta-analysis.

Zain SM, Mohamed Z, Mohamed R.

J Gastroenterol Hepatol. 2015 Jan;30(1):21-7. doi: 10.1111/jgh.12714.

PMID:
25167786
19.

Genetic variability of GCKR alters lipid profiles in children with monogenic and autoimmune diabetes.

Tracz A, Madzio J, Gnys P, Malachowska B, Borowiec M, Wyka K, Jarosz-Chobot P, Mysliwiec M, Szadkowska A, Mlynarski W, Fendler W; PolPeDiab Study Group.

Exp Clin Endocrinol Diabetes. 2014 Oct;122(9):503-9. doi: 10.1055/s-0034-1375648. Epub 2014 Jun 11.

PMID:
24918535
20.

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