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Vwf K1362A resulted in failure of protein synthesis in mice.

Sanda N, Suzuki N, Suzuki A, Kanematsu T, Kishimoto M, Hasuwa H, Takagi A, Kojima T, Matsushita T, Nakamura S.

Int J Hematol. 2018 Apr;107(4):428-435. doi: 10.1007/s12185-017-2394-y. Epub 2018 Feb 1.


Von Willebrand factor protects against acute CCl4-induced hepatotoxicity through phospho-p38 MAPK signaling pathway inhibition.

Sun HJ, Chen J, Zhang H, Ni B, van Velkinburgh JC, Liu Y, Wu YZ, Yang X.

Immunol Res. 2017 Oct;65(5):1046-1058. doi: 10.1007/s12026-017-8946-7.


Von Willebrand factor deficiency reduces liver fibrosis in mice.

Joshi N, Kopec AK, Ray JL, Cline-Fedewa H, Groeneveld DJ, Lisman T, Luyendyk JP.

Toxicol Appl Pharmacol. 2017 Aug 1;328:54-59. doi: 10.1016/j.taap.2017.05.018. Epub 2017 May 17.


von Willebrand factor contributes to poor outcome in a mouse model of intracerebral haemorrhage.

Zhu X, Cao Y, Wei L, Cai P, Xu H, Luo H, Bai X, Lu L, Liu JR, Fan W, Zhao BQ.

Sci Rep. 2016 Oct 26;6:35901. doi: 10.1038/srep35901.


Shear-Resistant Binding to von Willebrand Factor Allows Staphylococcus lugdunensis to Adhere to the Cardiac Valves and Initiate Endocarditis.

Liesenborghs L, Peetermans M, Claes J, Veloso TR, Vandenbriele C, Criel M, Lox M, Peetermans WE, Heilbronner S, de Groot PG, Vanassche T, Hoylaerts MF, Verhamme P.

J Infect Dis. 2016 Apr 1;213(7):1148-56. doi: 10.1093/infdis/jiv773. Epub 2016 Jan 6.


Endocardial Endothelial Dysfunction Progressively Disrupts Initially Anti then Pro-Thrombotic Pathways in Heart Failure Mice.

Schoner A, Tyrrell C, Wu M, Gelow JM, Hayes AA, Lindner JR, Thornburg KL, Hasan W.

PLoS One. 2015 Nov 13;10(11):e0142940. doi: 10.1371/journal.pone.0142940. eCollection 2015.


A novel role for von Willebrand factor in the pathogenesis of experimental cerebral malaria.

O'Regan N, Gegenbauer K, O'Sullivan JM, Maleki S, Brophy TM, Dalton N, Chion A, Fallon PG, Grau GE, Budde U, Smith OP, Craig AG, Preston RJ, O'Donnell JS.

Blood. 2016 Mar 3;127(9):1192-201. doi: 10.1182/blood-2015-07-654921. Epub 2015 Oct 28.


Relevant role of von Willebrand factor in neutrophil recruitment in a mouse sepsis model involving cecal ligation and puncture.

Kasuda S, Matsui H, Ono S, Matsunari Y, Nishio K, Shima M, Hatake K, Sugimoto M.

Haematologica. 2016 Feb;101(2):e52-4. doi: 10.3324/haematol.2015.135434. Epub 2015 Oct 22. No abstract available.


Platelet-derived VWF is not essential for normal thrombosis and hemostasis but fosters ischemic stroke injury in mice.

Verhenne S, Denorme F, Libbrecht S, Vandenbulcke A, Pareyn I, Deckmyn H, Lambrecht A, Nieswandt B, Kleinschnitz C, Vanhoorelbeke K, De Meyer SF.

Blood. 2015 Oct 1;126(14):1715-22. doi: 10.1182/blood-2015-03-632901. Epub 2015 Jul 24.


Molecular Imaging of Platelet-Endothelial Interactions and Endothelial von Willebrand Factor in Early and Mid-Stage Atherosclerosis.

Shim CY, Liu YN, Atkinson T, Xie A, Foster T, Davidson BP, Treible M, Qi Y, López JA, Munday A, Ruggeri Z, Lindner JR.

Circ Cardiovasc Imaging. 2015 Jul;8(7):e002765. doi: 10.1161/CIRCIMAGING.114.002765.


Choline Transporter-Like Protein-2: New von Willebrand Factor-Binding Partner Involved in Antibody-Mediated Neutrophil Activation and Transfusion-Related Acute Lung Injury.

Bayat B, Tjahjono Y, Berghöfer H, Werth S, Deckmyn H, De Meyer SF, Sachs UJ, Santoso S.

Arterioscler Thromb Vasc Biol. 2015 Jul;35(7):1616-22. doi: 10.1161/ATVBAHA.115.305259. Epub 2015 Apr 30.


von Willebrand factor arginine 1205 substitution results in accelerated macrophage-dependent clearance in vivo.

Rawley O, O'Sullivan JM, Chion A, Keyes S, Lavin M, van Rooijen N, Brophy TM, Fallon P, Preston RJ, O'Donnell JS.

J Thromb Haemost. 2015 May;13(5):821-6. doi: 10.1111/jth.12875. Epub 2015 Apr 13.


Increased hematopoiesis in long-term bone marrow cultures and reduced irradiation-induced pulmonary fibrosis in Von Willebrand factor homologous deletion recombinant mice.

Rhieu BH, Epperly MW, Cao S, Franicola D, Shields D, Goff J, Wang H, Greenberger JS.

In Vivo. 2014 Jul-Aug;28(4):449-56.


Adhesion of Staphylococcus aureus to the vessel wall under flow is mediated by von Willebrand factor-binding protein.

Claes J, Vanassche T, Peetermans M, Liesenborghs L, Vandenbriele C, Vanhoorelbeke K, Missiakas D, Schneewind O, Hoylaerts MF, Heying R, Verhamme P.

Blood. 2014 Sep 4;124(10):1669-76. doi: 10.1182/blood-2014-02-558890. Epub 2014 Jun 20.


Accelerated uptake of VWF/platelet complexes in macrophages contributes to VWD type 2B-associated thrombocytopenia.

Casari C, Du V, Wu YP, Kauskot A, de Groot PG, Christophe OD, Denis CV, de Laat B, Lenting PJ.

Blood. 2013 Oct 17;122(16):2893-902. doi: 10.1182/blood-2013-03-493312. Epub 2013 Aug 14.


Endothelial Von Willebrand factor promotes blood-brain barrier flexibility and provides protection from hypoxia and seizures in mice.

Suidan GL, Brill A, De Meyer SF, Voorhees JR, Cifuni SM, Cabral JE, Wagner DD.

Arterioscler Thromb Vasc Biol. 2013 Sep;33(9):2112-20. doi: 10.1161/ATVBAHA.113.301362. Epub 2013 Jul 3.


Hypoxia results in upregulation and de novo activation of von Willebrand factor expression in lung endothelial cells.

Mojiri A, Nakhaii-Nejad M, Phan WL, Kulak S, Radziwon-Balicka A, Jurasz P, Michelakis E, Jahroudi N.

Arterioscler Thromb Vasc Biol. 2013 Jun;33(6):1329-38. doi: 10.1161/ATVBAHA.113.301359. Epub 2013 Apr 11. Erratum in: Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):e123.


A murine model to characterize the antithrombotic effect of molecules targeting human von Willebrand factor.

Navarrete AM, Casari C, Legendre P, Marx I, Hu JR, Lenting PJ, Christophe OD, Denis CV.

Blood. 2012 Sep 27;120(13):2723-32. Epub 2012 Aug 20.


Contribution of platelet vs. endothelial VWF to platelet adhesion and hemostasis.

Kanaji S, Fahs SA, Shi Q, Haberichter SL, Montgomery RR.

J Thromb Haemost. 2012 Aug;10(8):1646-52. doi: 10.1111/j.1538-7836.2012.04797.x.


In vivo analysis of the role of O-glycosylations of von Willebrand factor.

Badirou I, Kurdi M, Legendre P, Rayes J, Bryckaert M, Casari C, Lenting PJ, Christophe OD, Denis CV.

PLoS One. 2012;7(5):e37508. doi: 10.1371/journal.pone.0037508. Epub 2012 May 17.

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