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Mechanistic insight into the pathology of polyalanine expansion disorders revealed by a mouse model for X linked hypopituitarism.

Hughes J, Piltz S, Rogers N, McAninch D, Rowley L, Thomas P.

PLoS Genet. 2013;9(3):e1003290. doi: 10.1371/journal.pgen.1003290. Epub 2013 Mar 7.


Sox3 functions in a cell-autonomous manner to regulate spermatogonial differentiation in mice.

Laronda MM, Jameson JL.

Endocrinology. 2011 Apr;152(4):1606-15. doi: 10.1210/en.2010-1249. Epub 2011 Jan 19.


Absence of SOX3 in the developing marsupial gonad is not consistent with a conserved role in mammalian sex determination.

Pask AJ, Harry JL, Renfree MB, Marshall Graves JA.

Genesis. 2000 Aug;27(4):145-52.


Abnormal Cell Sorting Underlies the Unique X-Linked Inheritance of PCDH19 Epilepsy.

Pederick DT, Richards KL, Piltz SG, Kumar R, Mincheva-Tasheva S, Mandelstam SA, Dale RC, Scheffer IE, Gecz J, Petrou S, Hughes JN, Thomas PQ.

Neuron. 2018 Jan 3;97(1):59-66.e5. doi: 10.1016/j.neuron.2017.12.005.


SOX3 deletion in mouse and human is associated with persistence of the craniopharyngeal canal.

Alatzoglou KS, Azriyanti A, Rogers N, Ryan F, Curry N, Noakes C, Bignell P, Hall GW, Littooij AS, Saunders D, Thomas P, Stewart H, Dattani MT.

J Clin Endocrinol Metab. 2014 Dec;99(12):E2702-8. doi: 10.1210/jc.2014-1160.


Dbx1 is a direct target of SOX3 in the spinal cord.

Rogers N, McAninch D, Thomas P.

PLoS One. 2014 Apr 21;9(4):e95356. doi: 10.1371/journal.pone.0095356. eCollection 2014.


Reciprocal repression between Sox3 and snail transcription factors defines embryonic territories at gastrulation.

Acloque H, Ocaña OH, Matheu A, Rizzoti K, Wise C, Lovell-Badge R, Nieto MA.

Dev Cell. 2011 Sep 13;21(3):546-58. doi: 10.1016/j.devcel.2011.07.005.


Sox3 is required for gonadal function, but not sex determination, in males and females.

Weiss J, Meeks JJ, Hurley L, Raverot G, Frassetto A, Jameson JL.

Mol Cell Biol. 2003 Nov;23(22):8084-91.


Copper-binding-site-null SOD1 causes ALS in transgenic mice: aggregates of non-native SOD1 delineate a common feature.

Wang J, Slunt H, Gonzales V, Fromholt D, Coonfield M, Copeland NG, Jenkins NA, Borchelt DR.

Hum Mol Genet. 2003 Nov 1;12(21):2753-64. Epub 2003 Sep 9.


The SRY gene HMG-box in micro- and megabats.

Bullejos M, Sánchez A, Burgos M, Jiménez R, Díaz De La Guardia R.

Cytogenet Cell Genet. 2000;88(1-2):30-4.


Direct transcriptional regulation of Six6 is controlled by SoxB1 binding to a remote forebrain enhancer.

Lee B, Rizzoti K, Kwon DS, Kim SY, Oh S, Epstein DJ, Son Y, Yoon J, Baek K, Jeong Y.

Dev Biol. 2012 Jun 15;366(2):393-403. doi: 10.1016/j.ydbio.2012.04.023. Epub 2012 Apr 25.


An interstitial deletion-insertion involving chromosomes 2p25.3 and Xq27.1, near SOX3, causes X-linked recessive hypoparathyroidism.

Bowl MR, Nesbit MA, Harding B, Levy E, Jefferson A, Volpi E, Rizzoti K, Lovell-Badge R, Schlessinger D, Whyte MP, Thakker RV.

J Clin Invest. 2005 Oct;115(10):2822-31. Epub 2005 Sep 15.


Related function of mouse SOX3, SOX9, and SRY HMG domains assayed by male sex determination.

Bergstrom DE, Young M, Albrecht KH, Eicher EM.

Genesis. 2000 Nov-Dec;28(3-4):111-24.


Sequentially acting Sox transcription factors in neural lineage development.

Bergsland M, Ramsköld D, Zaouter C, Klum S, Sandberg R, Muhr J.

Genes Dev. 2011 Dec 1;25(23):2453-64. doi: 10.1101/gad.176008.111. Epub 2011 Nov 15.


Genomic code for Sox2 binding uncovers its regulatory role in Six3 activation in the forebrain.

Lee B, Song H, Rizzoti K, Son Y, Yoon J, Baek K, Jeong Y.

Dev Biol. 2013 Sep 15;381(2):491-501. doi: 10.1016/j.ydbio.2013.06.016. Epub 2013 Jun 19.


A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes.

Gubbay J, Collignon J, Koopman P, Capel B, Economou A, Münsterberg A, Vivian N, Goodfellow P, Lovell-Badge R.

Nature. 1990 Jul 19;346(6281):245-50.


Regulation of mesodermal precursor production by low-level expression of B1 Sox genes in the caudal lateral epiblast.

Yoshida M, Uchikawa M, Rizzoti K, Lovell-Badge R, Takemoto T, Kondoh H.

Mech Dev. 2014 May;132:59-68. doi: 10.1016/j.mod.2014.01.003. Epub 2014 Feb 6.


Complex genome-wide transcription dynamics orchestrated by Blimp1 for the specification of the germ cell lineage in mice.

Kurimoto K, Yabuta Y, Ohinata Y, Shigeta M, Yamanaka K, Saitou M.

Genes Dev. 2008 Jun 15;22(12):1617-35. doi: 10.1101/gad.1649908.


SOX3 is required during the formation of the hypothalamo-pituitary axis.

Rizzoti K, Brunelli S, Carmignac D, Thomas PQ, Robinson IC, Lovell-Badge R.

Nat Genet. 2004 Mar;36(3):247-55. Epub 2004 Feb 15.


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