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Items: 1 to 20 of 203

1.

Chronic Stimulation of Renin Cells Leads to Vascular Pathology.

Oka M, Medrano S, Sequeira-Lόpez MLS, Gómez RA.

Hypertension. 2017 Jul;70(1):119-128. doi: 10.1161/HYPERTENSIONAHA.117.09283. Epub 2017 May 22.

2.

Long-Range Control of Renin Gene Expression in Tsukuba Hypertensive Mice.

Ushiki A, Matsuzaki H, Ishida J, Fukamizu A, Tanimoto K.

PLoS One. 2016 Nov 18;11(11):e0166974. doi: 10.1371/journal.pone.0166974. eCollection 2016.

3.

Collecting Duct Renin Does Not Mediate DOCA-Salt Hypertension or Renal Injury.

Song K, Stuart D, Abraham N, Wang F, Wang S, Yang T, Sigmund CD, Kohan DE, Ramkumar N.

PLoS One. 2016 Jul 28;11(7):e0159872. doi: 10.1371/journal.pone.0159872. eCollection 2016.

4.

Direct renin inhibition with aliskiren improves ischemia-induced neovascularization: blood pressure-independent effect.

Desjarlais M, Dussault S, Dhahri W, Mathieu R, Rivard A.

Atherosclerosis. 2015 Oct;242(2):450-60. doi: 10.1016/j.atherosclerosis.2015.08.009. Epub 2015 Aug 8.

PMID:
26295797
5.

Viral transduction of renin rapidly establishes persistent hypertension in diverse murine strains.

Harlan SM, Ostroski RA, Coskun T, Yantis LD, Breyer MD, Heuer JG.

Am J Physiol Regul Integr Comp Physiol. 2015 Sep;309(5):R467-74. doi: 10.1152/ajpregu.00106.2015. Epub 2015 Jun 24.

6.

Cells of renin lineage are adult pluripotent progenitors in experimental glomerular disease.

Pippin JW, Kaverina NV, Eng DG, Krofft RD, Glenn ST, Duffield JS, Gross KW, Shankland SJ.

Am J Physiol Renal Physiol. 2015 Aug 15;309(4):F341-58. doi: 10.1152/ajprenal.00438.2014. Epub 2015 Jun 10.

7.

Collecting duct-specific knockout of renin attenuates angiotensin II-induced hypertension.

Ramkumar N, Stuart D, Rees S, Hoek AV, Sigmund CD, Kohan DE.

Am J Physiol Renal Physiol. 2014 Oct 15;307(8):F931-8. doi: 10.1152/ajprenal.00367.2014. Epub 2014 Aug 13.

8.

Overexpression of Renin in the collecting duct causes elevated blood pressure.

Ramkumar N, Ying J, Stuart D, Kohan DE.

Am J Hypertens. 2013 Aug;26(8):965-72. doi: 10.1093/ajh/hpt071. Epub 2013 May 23.

PMID:
23702969
9.

Structural analysis suggests that renin is released by compound exocytosis.

Steppan D, Zügner A, Rachel R, Kurtz A.

Kidney Int. 2013 Feb;83(2):233-41. doi: 10.1038/ki.2012.392. Epub 2012 Dec 12.

10.

Preservation of intracellular renin expression is insufficient to compensate for genetic loss of secreted renin.

Xu D, Borges GR, Grobe JL, Pelham CJ, Yang B, Sigmund CD.

Hypertension. 2009 Dec;54(6):1240-7. doi: 10.1161/HYPERTENSIONAHA.109.138677. Epub 2009 Oct 12.

11.

Increased energy expenditure, dietary fat wasting, and resistance to diet-induced obesity in mice lacking renin.

Takahashi N, Li F, Hua K, Deng J, Wang CH, Bowers RR, Bartness TJ, Kim HS, Harp JB.

Cell Metab. 2007 Dec;6(6):506-12.

12.

Calcineurin independent development of myocardial hypertrophy in transgenic rats overexpressing the mouse renin gene, TGR(mREN2)27.

Diedrichs H, Mei C, Frank KF, Boelck B, Schwinger RH.

J Mol Med (Berl). 2004 Oct;82(10):688-95. Epub 2004 Aug 20.

PMID:
15322704
13.

Renin cells are precursors for multiple cell types that switch to the renin phenotype when homeostasis is threatened.

Sequeira López ML, Pentz ES, Nomasa T, Smithies O, Gomez RA.

Dev Cell. 2004 May;6(5):719-28.

14.

Ablation of renin-expressing juxtaglomerular cells results in a distinct kidney phenotype.

Pentz ES, Moyano MA, Thornhill BA, Sequeira Lopez ML, Gomez RA.

Am J Physiol Regul Integr Comp Physiol. 2004 Mar;286(3):R474-83. Epub 2003 Oct 16.

15.

Glia- and neuron-specific expression of the renin-angiotensin system in brain alters blood pressure, water intake, and salt preference.

Morimoto S, Cassell MD, Sigmund CD.

J Biol Chem. 2002 Sep 6;277(36):33235-41. Epub 2002 Jun 21.

16.

Contribution of circulating renin to local synthesis of angiotensin peptides in the heart.

Prescott G, Silversides DW, Chiu SM, Reudelhuber TL.

Physiol Genomics. 2000 Nov 9;4(1):67-73.

PMID:
11074015
17.

Granulation rescue and developmental marking of juxtaglomerular cells using "piggy-BAC" recombination of the mouse ren locus.

Mullins LJ, Payne CM, Kotelevtseva N, Brooker G, Fleming S, Harris S, Mullins JJ.

J Biol Chem. 2000 Dec 22;275(51):40378-84.

18.

Transgenic models as tools for studying the regulation of human renin expression.

Sinn PL, Sigmund CD.

Regul Pept. 2000 Jan 29;86(1-3):77-82. Review.

PMID:
10672905
20.

Renin-1 is essential for normal renal juxtaglomerular cell granulation and macula densa morphology.

Clark AF, Sharp MG, Morley SD, Fleming S, Peters J, Mullins JJ.

J Biol Chem. 1997 Jul 18;272(29):18185-90.

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