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Plasminogen Activator Inhibitor-1 Is Critical in Alcohol-Enhanced Acute Lung Injury in Mice.

Poole LG, Massey VL, Siow DL, Torres-Gonzáles E, Warner NL, Luyendyk JP, Ritzenthaler JD, Roman J, Arteel GE.

Am J Respir Cell Mol Biol. 2017 Sep;57(3):315-323. doi: 10.1165/rcmb.2016-0184OC.


Circadian fluctuations in circulating plasminogen activator inhibitor-1 are independent of feeding cycles in mice.

Oishi K, Ohkura N, Yasumoto Y, Yamamoto S.

Chronobiol Int. 2017;34(2):254-259. doi: 10.1080/07420528.2016.1256299. Epub 2016 Dec 1.


Effect of Olmesartan on the Level of Oral Cancer Risk Factor PAI1.

Vassiliou S, Nkenke E, Lefantzis N, Ioannidis A, Yapijakis C, Zoga M, Papakosta V, Derka S, Nikolaou C, Vairaktaris E.

Anticancer Res. 2016 Nov;36(11):6093-6096.


Pharmacological Targeting of Plasminogen Activator Inhibitor-1 Decreases Vascular Smooth Muscle Cell Migration and Neointima Formation.

Ji Y, Weng Z, Fish P, Goyal N, Luo M, Myears SP, Strawn TL, Chandrasekar B, Wu J, Fay WP.

Arterioscler Thromb Vasc Biol. 2016 Nov;36(11):2167-2175. Epub 2016 Sep 22.


PAI-1 deficiency increases the trophic effects of hypergastrinemia in the gastric corpus mucosa.

Fossmark R, Rao S, Mjønes P, Munkvold B, Flatberg A, Varro A, Thommesen L, Nørsett KG.

Peptides. 2016 May;79:83-94. doi: 10.1016/j.peptides.2016.03.016. Epub 2016 Mar 30.


Plasminogen activator inhibitor 1, fibroblast apoptosis resistance, and aging-related susceptibility to lung fibrosis.

Huang WT, Akhter H, Jiang C, MacEwen M, Ding Q, Antony V, Thannickal VJ, Liu RM.

Exp Gerontol. 2015 Jan;61:62-75. doi: 10.1016/j.exger.2014.11.018. Epub 2014 Nov 28.


PAI-1 inhibits development of chronic otitis media and tympanosclerosis in a mouse model of otitis media.

Shin SG, Koh SH, Woo CH, Lim JH.

Acta Otolaryngol. 2014 Dec;134(12):1231-8. doi: 10.3109/00016489.2014.940554.


Effects of a high-fat diet on spontaneous metastasis of Lewis lung carcinoma in plasminogen activator inhibitor-1 deficient and wild-type mice.

Yan L, DeMars LC.

PLoS One. 2014 Oct 30;9(10):e110869. doi: 10.1371/journal.pone.0110869. eCollection 2014. Erratum in: PLoS One. 2015;10(3):e0118115.


Nocturnal light exposure alters hepatic Pai-1 expression by stimulating the adrenal pathway in C3H mice.

Aoshima Y, Sakakibara H, Suzuki TA, Yamazaki S, Shimoi K.

Exp Anim. 2014;63(3):331-8.


Systemic inhibition and liver-specific over-expression of PAI-1 failed to improve survival in all-inclusive populations or homogenous cohorts of CLP mice.

Raeven P, Drechsler S, Weixelbaumer KM, Bastelica D, Peiretti F, Klotz A, Jafarmadar M, Redl H, Bahrami S, Alessi MC, Declerck PJ, Osuchowski MF.

J Thromb Haemost. 2014 Jun;12(6):958-69. doi: 10.1111/jth.12565.


Plasminogen activator inhibitor-1 deficiency ameliorates insulin resistance and hyperlipidemia but not bone loss in obese female mice.

Tamura Y, Kawao N, Yano M, Okada K, Matsuo O, Kaji H.

Endocrinology. 2014 May;155(5):1708-17. doi: 10.1210/en.2013-1888. Epub 2014 Feb 28.


Plasminogen activator inhibitor-1 deficiency augments visceral mesothelial organization, intrapleural coagulation, and lung restriction in mice with carbon black/bleomycin-induced pleural injury.

Tucker TA, Jeffers A, Alvarez A, Owens S, Koenig K, Quaid B, Komissarov AA, Florova G, Kothari H, Pendurthi U, Mohan Rao LV, Idell S.

Am J Respir Cell Mol Biol. 2014 Feb;50(2):316-27. doi: 10.1165/rcmb.2013-0300OC.


Peptidergic regulation of plasminogen activator inhibitor-1 gene expression in vivo.

Gingles NA, Bai H, Miles LA, Parmer RJ.

J Thromb Haemost. 2013 Sep;11(9):1707-15. doi: 10.1111/jth.12333.


Global gene expression profiling in PAI-1 knockout murine heart and kidney: molecular basis of cardiac-selective fibrosis.

Ghosh AK, Murphy SB, Kishore R, Vaughan DE.

PLoS One. 2013 May 28;8(5):e63825. doi: 10.1371/journal.pone.0063825. Print 2013.


Plasminogen activator inhibitor-1 is involved in streptozotocin-induced bone loss in female mice.

Tamura Y, Kawao N, Okada K, Yano M, Okumoto K, Matsuo O, Kaji H.

Diabetes. 2013 Sep;62(9):3170-9. doi: 10.2337/db12-1552. Epub 2013 May 28.


The role of plasminogen activator inhibitor-1 in gastric mucosal protection.

Kenny S, Steele I, Lyons S, Moore AR, Murugesan SV, Tiszlavicz L, Dimaline R, Pritchard DM, Varro A, Dockray GJ.

Am J Physiol Gastrointest Liver Physiol. 2013 May 1;304(9):G814-22. doi: 10.1152/ajpgi.00017.2013. Epub 2013 Mar 14.


Glucose-independent persistence of PAI-1 gene expression and H3K4 tri-methylation in type 1 diabetic mouse endothelium: implication in metabolic memory.

Takizawa F, Mizutani S, Ogawa Y, Sawada N.

Biochem Biophys Res Commun. 2013 Mar 29;433(1):66-72. doi: 10.1016/j.bbrc.2013.02.064. Epub 2013 Feb 26.


A non-lethal traumatic/hemorrhagic insult strongly modulates the compartment-specific PAI-1 response in the subsequent polymicrobial sepsis.

Raeven P, Salibasic A, Drechsler S, Weixelbaumer KM, Jafarmadar M, van Griensven M, Bahrami S, Osuchowski MF.

PLoS One. 2013;8(2):e55467. doi: 10.1371/journal.pone.0055467. Epub 2013 Feb 8.


The vitronectin-binding domain of plasminogen activator inhibitor-1 plays an important functional role in lipopolysaccharide-induced lethality in mice.

Narasaki R, Xu Z, Liang Z, Fung LC, Donahue D, Castellino FJ, Ploplis VA.

J Thromb Haemost. 2012 Dec;10(12):2618-21. doi: 10.1111/jth.12032. No abstract available.


Associations between plasma PAI-1 concentrations and its expressions in various organs in obese model mice.

Ohkura N, Shirakura M, Nakatani E, Oishi K, Atsumi G.

Thromb Res. 2012 Dec;130(6):e301-4. doi: 10.1016/j.thromres.2012.08.297. Epub 2012 Oct 15. No abstract available.


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