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Items: 1 to 20 of 123

1.

Fatty acid synthase regulates the pathogenicity of Th17 cells.

Young KE, Flaherty S, Woodman KM, Sharma-Walia N, Reynolds JM.

J Leukoc Biol. 2017 Nov;102(5):1229-1235. doi: 10.1189/jlb.3AB0417-159RR. Epub 2017 Aug 28.

2.

Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma.

Che L, Pilo MG, Cigliano A, Latte G, Simile MM, Ribback S, Dombrowski F, Evert M, Chen X, Calvisi DF.

Cell Cycle. 2017 Mar 19;16(6):499-507. doi: 10.1080/15384101.2017.1282586. Epub 2017 Jan 24.

3.

Fatty acid synthase as a factor required for exercise-induced cognitive enhancement and dentate gyrus cellular proliferation.

Chorna NE, Santos-Soto IJ, Carballeira NM, Morales JL, de la Nuez J, Cátala-Valentin A, Chornyy AP, Vázquez-Montes A, De Ortiz SP.

PLoS One. 2013 Nov 5;8(11):e77845. doi: 10.1371/journal.pone.0077845. eCollection 2013.

4.

Muscle lipogenesis balances insulin sensitivity and strength through calcium signaling.

Funai K, Song H, Yin L, Lodhi IJ, Wei X, Yoshino J, Coleman T, Semenkovich CF.

J Clin Invest. 2013 Mar;123(3):1229-40. doi: 10.1172/JCI65726. Epub 2013 Feb 8. Erratum in: J Clin Invest. 2013 Aug 1;123(8):3634.

5.

Fatty acid synthase modulates homeostatic responses to myocardial stress.

Razani B, Zhang H, Schulze PC, Schilling JD, Verbsky J, Lodhi IJ, Topkara VK, Feng C, Coleman T, Kovacs A, Kelly DP, Saffitz JE, Dorn GW 2nd, Nichols CG, Semenkovich CF.

J Biol Chem. 2011 Sep 2;286(35):30949-61. doi: 10.1074/jbc.M111.230508. Epub 2011 Jul 8.

6.

Inactivation of hypothalamic FAS protects mice from diet-induced obesity and inflammation.

Chakravarthy MV, Zhu Y, Yin L, Coleman T, Pappan KL, Marshall CA, McDaniel ML, Semenkovich CF.

J Lipid Res. 2009 Apr;50(4):630-40. doi: 10.1194/jlr.M800379-JLR200. Epub 2008 Nov 22.

7.

Fatty acid synthase inhibition with Orlistat promotes apoptosis and reduces cell growth and lymph node metastasis in a mouse melanoma model.

Carvalho MA, Zecchin KG, Seguin F, Bastos DC, Agostini M, Rangel AL, Veiga SS, Raposo HF, Oliveira HC, Loda M, Coletta RD, Graner E.

Int J Cancer. 2008 Dec 1;123(11):2557-65. doi: 10.1002/ijc.23835.

8.

Effect of centrally administered C75, a fatty acid synthase inhibitor, on gastric emptying and gastrointestinal transit in mice.

Li LF, Lu YY, Xiong W, Liu JY, Chen Q.

Eur J Pharmacol. 2008 Oct 24;595(1-3):90-4. doi: 10.1016/j.ejphar.2008.07.055. Epub 2008 Jul 31.

PMID:
18706411
9.

Nicotine-induced activation of AMP-activated protein kinase inhibits fatty acid synthase in 3T3L1 adipocytes: a role for oxidant stress.

An Z, Wang H, Song P, Zhang M, Geng X, Zou MH.

J Biol Chem. 2007 Sep 14;282(37):26793-801. Epub 2007 Jul 16.

10.

Inhibition of hypothalamic fatty acid synthase triggers rapid activation of fatty acid oxidation in skeletal muscle.

Cha SH, Hu Z, Chohnan S, Lane MD.

Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14557-62. Epub 2005 Oct 3.

11.

Inhibition of fatty acid synthase prevents preadipocyte differentiation.

Schmid B, Rippmann JF, Tadayyon M, Hamilton BS.

Biochem Biophys Res Commun. 2005 Mar 25;328(4):1073-82.

PMID:
15707987
12.

Fatty acid synthesis is essential in embryonic development: fatty acid synthase null mutants and most of the heterozygotes die in utero.

Chirala SS, Chang H, Matzuk M, Abu-Elheiga L, Mao J, Mahon K, Finegold M, Wakil SJ.

Proc Natl Acad Sci U S A. 2003 May 27;100(11):6358-63. Epub 2003 May 8.

13.

Expression of FAS within hypothalamic neurons: a model for decreased food intake after C75 treatment.

Kim EK, Miller I, Landree LE, Borisy-Rudin FF, Brown P, Tihan T, Townsend CA, Witters LA, Moran TH, Kuhajda FP, Ronnett GV.

Am J Physiol Endocrinol Metab. 2002 Nov;283(5):E867-79.

14.

Effect of a fatty acid synthase inhibitor on food intake and expression of hypothalamic neuropeptides.

Shimokawa T, Kumar MV, Lane MD.

Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):66-71. Epub 2001 Dec 26.

15.
16.

Structure of mouse fatty acid synthase mRNA. Identification of the two NADPH binding sites.

Paulauskis JD, Sul HS.

Biochem Biophys Res Commun. 1989 Feb 15;158(3):690-5.

PMID:
2920037
18.

A key role of nuclear factor Y in the refeeding response of fatty acid synthase in adipocytes.

Nishi-Tatsumi M, Yahagi N, Takeuchi Y, Toya N, Takarada A, Murayama Y, Aita Y, Sawada Y, Piao X, Oya Y, Shikama A, Masuda Y, Kubota M, Izumida Y, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Kawakami Y, Kadowaki T, Yamada N, Shimano H.

FEBS Lett. 2017 Apr;591(7):965-978. doi: 10.1002/1873-3468.12620. Epub 2017 Mar 27.

19.

Fatty acid synthesis configures the plasma membrane for inflammation in diabetes.

Wei X, Song H, Yin L, Rizzo MG, Sidhu R, Covey DF, Ory DS, Semenkovich CF.

Nature. 2016 Nov 10;539(7628):294-298. doi: 10.1038/nature20117. Epub 2016 Nov 2.

20.

TSH/TSHR Signaling Suppresses Fatty Acid Synthase (FASN) Expression in Adipocytes.

Chen J, Ren J, Jing Q, Lu S, Zhang Y, Liu Y, Yu C, Gao P, Zong C, Li X, Wang X.

J Cell Physiol. 2015 Sep;230(9):2233-9. doi: 10.1002/jcp.24952.

PMID:
25655684

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