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Items: 1 to 20 of 1267

1.

Cerebellar synapse properties and cerebellum-dependent motor and non-motor performance in Dp71-null mice.

Helleringer R, Le Verger D, Li X, Izabelle C, Chaussenot R, Belmaati-Cherkaoui M, Dammak R, Decottignies P, Daniel H, Galante M, Vaillend C.

Dis Model Mech. 2018 Jul 10;11(7). pii: dmm033258. doi: 10.1242/dmm.033258.

2.

Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation.

Zhao J, Zhang L, Mu X, Doebelin C, Nguyen W, Wallace C, Reay DP, McGowan SJ, Corbo L, Clemens PR, Wilson GM, Watkins SC, Solt LA, Cameron MD, Huard J, Niedernhofer LJ, Kamenecka TM, Robbins PD.

PLoS Biol. 2018 Jun 11;16(6):e2004663. doi: 10.1371/journal.pbio.2004663. eCollection 2018 Jun.

3.

Variable rescue of microtubule and physiological phenotypes in mdx muscle expressing different miniaturized dystrophins.

Nelson DM, Lindsay A, Judge LM, Duan D, Chamberlain JS, Lowe DA, Ervasti JM.

Hum Mol Genet. 2018 Jun 15;27(12):2090-2100. doi: 10.1093/hmg/ddy113.

PMID:
29618008
4.

The dual CCR2/CCR5 chemokine receptor antagonist Cenicriviroc reduces macrophage infiltration and disease severity in Duchenne muscular dystrophy (Dmdmdx-4Cv) mice.

Liang F, Giordano C, Shang D, Li Q, Petrof BJ.

PLoS One. 2018 Mar 21;13(3):e0194421. doi: 10.1371/journal.pone.0194421. eCollection 2018.

5.

A dystrophic Duchenne mouse model for testing human antisense oligonucleotides.

Veltrop M, van Vliet L, Hulsker M, Claassens J, Brouwers C, Breukel C, van der Kaa J, Linssen MM, den Dunnen JT, Verbeek S, Aartsma-Rus A, van Putten M.

PLoS One. 2018 Feb 21;13(2):e0193289. doi: 10.1371/journal.pone.0193289. eCollection 2018.

6.

Mitochondrial content is preserved throughout disease progression in the mdx mouse model of Duchenne muscular dystrophy, regardless of taurine supplementation.

Barker RG, Wyckelsma VL, Xu H, Murphy RM.

Am J Physiol Cell Physiol. 2018 Apr 1;314(4):C483-C491. doi: 10.1152/ajpcell.00046.2017. Epub 2017 Dec 20.

PMID:
29351413
7.

Expression of CTGF/CCN2 in response to LPA is stimulated by fibrotic extracellular matrix via the integrin/FAK axis.

Riquelme-Guzmán C, Contreras O, Brandan E.

Am J Physiol Cell Physiol. 2018 Apr 1;314(4):C415-C427. doi: 10.1152/ajpcell.00013.2017. Epub 2017 Dec 27.

PMID:
29351412
8.

Inhibition of antigen presentation during AAV gene therapy using virus peptides.

Shao W, Chen X, Samulski RJ, Hirsch ML, Li C.

Hum Mol Genet. 2018 Feb 15;27(4):601-613. doi: 10.1093/hmg/ddx427.

PMID:
29272432
9.

Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy.

Amoasii L, Long C, Li H, Mireault AA, Shelton JM, Sanchez-Ortiz E, McAnally JR, Bhattacharyya S, Schmidt F, Grimm D, Hauschka SD, Bassel-Duby R, Olson EN.

Sci Transl Med. 2017 Nov 29;9(418). pii: eaan8081. doi: 10.1126/scitranslmed.aan8081. Erratum in: Sci Transl Med. 2018 Jan 24;10 (425):.

10.

Beneficial effects of high dose taurine treatment in juvenile dystrophic mdx mice are offset by growth restriction.

Terrill JR, Pinniger GJ, Nair KV, Grounds MD, Arthur PG.

PLoS One. 2017 Nov 2;12(11):e0187317. doi: 10.1371/journal.pone.0187317. eCollection 2017.

11.

Phosphodiesterase 4 inhibitor and phosphodiesterase 5 inhibitor combination therapy has antifibrotic and anti-inflammatory effects in mdx mice with Duchenne muscular dystrophy.

Nio Y, Tanaka M, Hirozane Y, Muraki Y, Okawara M, Hazama M, Matsuo T.

FASEB J. 2017 Dec;31(12):5307-5320. doi: 10.1096/fj.201700249R. Epub 2017 Aug 10.

PMID:
28798156
12.

In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice.

El Refaey M, Xu L, Gao Y, Canan BD, Adesanya TMA, Warner SC, Akagi K, Symer DE, Mohler PJ, Ma J, Janssen PML, Han R.

Circ Res. 2017 Sep 29;121(8):923-929. doi: 10.1161/CIRCRESAHA.117.310996. Epub 2017 Aug 8.

PMID:
28790199
13.

Dystrophic phenotype improvement in the diaphragm muscle of mdx mice by diacerhein.

Mâncio RD, Hermes TA, Macedo AB, Mizobuti DS, Rupcic IF, Minatel E.

PLoS One. 2017 Aug 7;12(8):e0182449. doi: 10.1371/journal.pone.0182449. eCollection 2017.

14.

ER stress disturbs SR/ER-mitochondria Ca2+ transfer: Implications in Duchenne muscular dystrophy.

Pauly M, Angebault-Prouteau C, Dridi H, Notarnicola C, Scheuermann V, Lacampagne A, Matecki S, Fauconnier J.

Biochim Biophys Acta Mol Basis Dis. 2017 Sep;1863(9):2229-2239. doi: 10.1016/j.bbadis.2017.06.009. Epub 2017 Jun 15.

PMID:
28625916
15.

RhoA/ROCK inhibition improves the beneficial effects of glucocorticoid treatment in dystrophic muscle: implications for stem cell depletion.

Mu X, Tang Y, Takayama K, Chen W, Lu A, Wang B, Weiss K, Huard J.

Hum Mol Genet. 2017 Aug 1;26(15):2813-2824. doi: 10.1093/hmg/ddx117.

16.

Intermittent glucocorticoid steroid dosing enhances muscle repair without eliciting muscle atrophy.

Quattrocelli M, Barefield DY, Warner JL, Vo AH, Hadhazy M, Earley JU, Demonbreun AR, McNally EM.

J Clin Invest. 2017 Jun 1;127(6):2418-2432. doi: 10.1172/JCI91445. Epub 2017 May 8.

17.

CRISPR-Cpf1 correction of muscular dystrophy mutations in human cardiomyocytes and mice.

Zhang Y, Long C, Li H, McAnally JR, Baskin KK, Shelton JM, Bassel-Duby R, Olson EN.

Sci Adv. 2017 Apr 12;3(4):e1602814. doi: 10.1126/sciadv.1602814. eCollection 2017 Apr.

18.

Spatial distribution and molecular dynamics of dystrophin glycoprotein components at the neuromuscular junction in vivo.

Aittaleb M, Martinez-Pena Y Valenzuela I, Akaaboune M.

J Cell Sci. 2017 May 15;130(10):1752-1759. doi: 10.1242/jcs.198358. Epub 2017 Mar 31.

19.

Loss of dystrophin is associated with increased myocardial stiffness in a model of left ventricular hypertrophy.

Donato M, Buchholz B, Morales C, Valdez L, Zaobornyj T, Baratta S, Paez DT, Matoso M, Vaccarino G, Chejtman D, Agüero O, Telayna J, Navia J, Hita A, Boveris A, Gelpi RJ.

Mol Cell Biochem. 2017 Aug;432(1-2):169-178. doi: 10.1007/s11010-017-3007-z. Epub 2017 Mar 18.

PMID:
28316061
20.

Low-Intensity Training and the C5a Complement Antagonist NOX-D21 Rescue the mdx Phenotype through Modulation of Inflammation.

Hyzewicz J, Tanihata J, Kuraoka M, Nitahara-Kasahara Y, Beylier T, Ruegg UT, Vater A, Takeda S.

Am J Pathol. 2017 May;187(5):1147-1161. doi: 10.1016/j.ajpath.2016.12.019. Epub 2017 Mar 18.

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