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Items: 1 to 20 of 45

1.

CYP7B1 Enzyme Deletion Impairs Reproductive Behaviors in Male Mice.

Oyola MG, Zuloaga DG, Carbone D, Malysz AM, Acevedo-Rodriguez A, Handa RJ, Mani SK.

Endocrinology. 2015 Jun;156(6):2150-61. doi: 10.1210/en.2014-1786. Epub 2015 Apr 7.

2.

Early onset of puberty and early ovarian failure in CYP7B1 knockout mice.

Omoto Y, Lathe R, Warner M, Gustafsson JA.

Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):2814-9. Epub 2005 Feb 14. Erratum in: Proc Natl Acad Sci U S A. 2006 May 23;103(21):8298.

3.

Ontogeny of the neurosteroid enzyme Cyp7b in the mouse.

Bean R, Seckl JR, Lathe R, Martin C.

Mol Cell Endocrinol. 2001 Mar 28;174(1-2):137-44.

PMID:
11306180
4.

Neurosteroid hydroxylase CYP7B: vivid reporter activity in dentate gyrus of gene-targeted mice and abolition of a widespread pathway of steroid and oxysterol hydroxylation.

Rose K, Allan A, Gauldie S, Stapleton G, Dobbie L, Dott K, Martin C, Wang L, Hedlund E, Seckl JR, Gustafsson JA, Lathe R.

J Biol Chem. 2001 Jun 29;276(26):23937-44. Epub 2001 Apr 4.

5.

Disruption of the oxysterol 7alpha-hydroxylase gene in mice.

Li-Hawkins J, Lund EG, Turley SD, Russell DW.

J Biol Chem. 2000 Jun 2;275(22):16536-42.

6.

Identification and characterization of a mouse oxysterol 7alpha-hydroxylase cDNA.

Schwarz M, Lund EG, Lathe R, Björkhem I, Russell DW.

J Biol Chem. 1997 Sep 19;272(38):23995-4001.

7.

The cholesterol metabolite 27-hydroxycholesterol promotes atherosclerosis via proinflammatory processes mediated by estrogen receptor alpha.

Umetani M, Ghosh P, Ishikawa T, Umetani J, Ahmed M, Mineo C, Shaul PW.

Cell Metab. 2014 Jul 1;20(1):172-82. doi: 10.1016/j.cmet.2014.05.013. Epub 2014 Jun 19.

8.

24S,25-Epoxycholesterol in mouse and rat brain.

Wang Y, Karu K, Meljon A, Turton J, Yau JL, Seckl JR, Wang Y, Griffiths WJ.

Biochem Biophys Res Commun. 2014 Jun 27;449(2):229-34. doi: 10.1016/j.bbrc.2014.05.012. Epub 2014 May 14.

9.

The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis.

DuSell CD, Nelson ER, Wang X, Abdo J, Mödder UI, Umetani M, Gesty-Palmer D, Javitt NB, Khosla S, McDonnell DP.

Endocrinology. 2010 Aug;151(8):3675-85. doi: 10.1210/en.2010-0080. Epub 2010 May 25.

10.

25-Hydroxycholesterol secreted by macrophages in response to Toll-like receptor activation suppresses immunoglobulin A production.

Bauman DR, Bitmansour AD, McDonald JG, Thompson BM, Liang G, Russell DW.

Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16764-9. doi: 10.1073/pnas.0909142106. Epub 2009 Sep 15.

11.

CYP7B1-mediated metabolism of 5alpha-androstane-3alpha,17beta-diol (3alpha-Adiol): a novel pathway for potential regulation of the cellular levels of androgens and neurosteroids.

Pettersson H, Lundqvist J, Oliw E, Norlin M.

Biochim Biophys Acta. 2009 Dec;1791(12):1206-15. doi: 10.1016/j.bbalip.2009.08.010. Epub 2009 Sep 2.

PMID:
19732851
12.

A novel cytochrome P450 expressed primarily in brain.

Stapleton G, Steel M, Richardson M, Mason JO, Rose KA, Morris RG, Lathe R.

J Biol Chem. 1995 Dec 15;270(50):29739-45.

13.

Estrogen receptor alpha and imprinting of the neonatal mouse ventral prostate by estrogen.

Omoto Y, Imamov O, Warner M, Gustafsson JA.

Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1484-9. Epub 2005 Jan 21. Erratum in: Proc Natl Acad Sci U S A. 2006 May 23;103(21):8298.

14.
15.

27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen.

Umetani M, Domoto H, Gormley AK, Yuhanna IS, Cummins CL, Javitt NB, Korach KS, Shaul PW, Mangelsdorf DJ.

Nat Med. 2007 Oct;13(10):1185-92. Epub 2007 Sep 16.

PMID:
17873880
16.

An endocrine pathway in the prostate, ERbeta, AR, 5alpha-androstane-3beta,17beta-diol, and CYP7B1, regulates prostate growth.

Weihua Z, Lathe R, Warner M, Gustafsson JA.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13589-94. Epub 2002 Oct 7. Erratum in: Proc Natl Acad Sci U S A. 2006 May 23;103(21):8298.

17.

Microarray analysis of hepatic gene expression identifies new genes involved in steatotic liver.

Guillén N, Navarro MA, Arnal C, Noone E, Arbonés-Mainar JM, Acín S, Surra JC, Muniesa P, Roche HM, Osada J.

Physiol Genomics. 2009 May 13;37(3):187-98. doi: 10.1152/physiolgenomics.90339.2008. Epub 2009 Mar 3.

18.

Expression cloning of an oxysterol 7alpha-hydroxylase selective for 24-hydroxycholesterol.

Li-Hawkins J, Lund EG, Bronson AD, Russell DW.

J Biol Chem. 2000 Jun 2;275(22):16543-9.

19.

Cytochrome P450s in the synthesis of cholesterol and bile acids--from mouse models to human diseases.

Lorbek G, Lewinska M, Rozman D.

FEBS J. 2012 May;279(9):1516-33. doi: 10.1111/j.1742-4658.2011.08432.x. Epub 2011 Dec 22. Review.

20.

Identification of oxysterol 7alpha-hydroxylase (Cyp7b1) as a novel retinoid-related orphan receptor alpha (RORalpha) (NR1F1) target gene and a functional cross-talk between RORalpha and liver X receptor (NR1H3).

Wada T, Kang HS, Angers M, Gong H, Bhatia S, Khadem S, Ren S, Ellis E, Strom SC, Jetten AM, Xie W.

Mol Pharmacol. 2008 Mar;73(3):891-9. Epub 2007 Nov 30.

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