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Items: 1 to 20 of 61

1.

Circadian Clock Is Involved in Regulation of Hepatobiliary Transport Mediated by Multidrug Resistance-Associated Protein 2.

Oh JH, Lee JH, Han DH, Cho S, Lee YJ.

J Pharm Sci. 2017 Sep;106(9):2491-2498. doi: 10.1016/j.xphs.2017.04.071. Epub 2017 May 4.

PMID:
28479363
2.

Novel Hg2+-induced nephropathy in rats and mice lacking Mrp2: evidence of axial heterogeneity in the handling of Hg2+ along the proximal tubule.

Zalups RK, Joshee L, Bridges CC.

Toxicol Sci. 2014 Nov;142(1):250-60. doi: 10.1093/toxsci/kfu171. Epub 2014 Aug 21.

3.

Glutathione status and the renal elimination of inorganic mercury in the Mrp2(-/-) mouse.

Bridges CC, Joshee L, van den Heuvel JJ, Russel FG, Zalups RK.

PLoS One. 2013 Sep 5;8(9):e73559. doi: 10.1371/journal.pone.0073559. eCollection 2013.

4.

Transportomics: screening for substrates of ABC transporters in body fluids using vesicular transport assays.

Krumpochova P, Sapthu S, Brouwers JF, de Haas M, de Vos R, Borst P, van de Wetering K.

FASEB J. 2012 Feb;26(2):738-47. doi: 10.1096/fj.11-195743. Epub 2011 Oct 27.

5.

Strain- and sex-dependent circadian changes in abcc2 transporter expression: implications for irinotecan chronotolerance in mouse ileum.

Okyar A, Piccolo E, Ahowesso C, Filipski E, Hossard V, Guettier C, La Sorda R, Tinari N, Iacobelli S, Lévi F.

PLoS One. 2011;6(6):e20393. doi: 10.1371/journal.pone.0020393. Epub 2011 Jun 3.

6.
7.

Transport of N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine, a metabolite of trichloroethylene, by mouse multidrug resistance associated protein 2 (Mrp2).

Tsirulnikov K, Abuladze N, Koag MC, Newman D, Scholz K, Bondar G, Zhu Q, Avliyakulov NK, Dekant W, Faull K, Kurtz I, Pushkin A.

Toxicol Appl Pharmacol. 2010 Apr 15;244(2):218-25. doi: 10.1016/j.taap.2009.12.035. Epub 2010 Jan 6.

8.

Characterization of mice lacking the multidrug resistance protein MRP2 (ABCC2).

Chu XY, Strauss JR, Mariano MA, Li J, Newton DJ, Cai X, Wang RW, Yabut J, Hartley DP, Evans DC, Evers R.

J Pharmacol Exp Ther. 2006 May;317(2):579-89. Epub 2006 Jan 18.

9.
10.

Constitutive rat multidrug-resistance protein 2 gene transcription is down-regulated by Y-box protein 1.

Geier A, Mertens PR, Gerloff T, Dietrich CG, En-Nia A, Kullak-Ublick GA, Karpen SJ, Matern S, Gartung C.

Biochem Biophys Res Commun. 2003 Sep 26;309(3):612-8.

PMID:
12963034
11.

Molecular cloning of the murine cMOAT ATPase.

Fritz F, Chen J, Hayes P, Sirotnak FM.

Biochim Biophys Acta. 2000 Jul 24;1492(2-3):531-6.

PMID:
11004524
12.

Functional analysis of a canalicular multispecific organic anion transporter cloned from rat liver.

Ito K, Suzuki H, Hirohashi T, Kume K, Shimizu T, Sugiyama Y.

J Biol Chem. 1998 Jan 16;273(3):1684-8.

13.

Transgenic expression of the human MRP2 transporter reduces cisplatin accumulation and nephrotoxicity in Mrp2-null mice.

Wen X, Buckley B, McCandlish E, Goedken MJ, Syed S, Pelis R, Manautou JE, Aleksunes LM.

Am J Pathol. 2014 May;184(5):1299-308. doi: 10.1016/j.ajpath.2014.01.025. Epub 2014 Mar 15.

14.

Generation and characterization of a novel multidrug resistance protein 2 humanized mouse line.

Scheer N, Balimane P, Hayward MD, Buechel S, Kauselmann G, Wolf CR.

Drug Metab Dispos. 2012 Nov;40(11):2212-8. doi: 10.1124/dmd.112.047605. Epub 2012 Aug 23.

15.

Metallothionein blocks oxidative DNA damage in vitro.

Qu W, Pi J, Waalkes MP.

Arch Toxicol. 2013 Feb;87(2):311-21. doi: 10.1007/s00204-012-0927-y. Epub 2012 Aug 23.

16.

Dose-dependent disposition of methotrexate in Abcc2 and Abcc3 gene knockout murine models.

Wang Z, Zhou Q, Kruh GD, Gallo JM.

Drug Metab Dispos. 2011 Nov;39(11):2155-61. doi: 10.1124/dmd.111.041228. Epub 2011 Aug 12.

17.

Effect of ABCC2 (MRP2) transport function on erythromycin metabolism.

Franke RM, Lancaster CS, Peer CJ, Gibson AA, Kosloske AM, Orwick SJ, Mathijssen RH, Figg WD, Baker SD, Sparreboom A.

Clin Pharmacol Ther. 2011 May;89(5):693-701. doi: 10.1038/clpt.2011.25. Epub 2011 Mar 30.

18.

Impact of Abcc2 (Mrp2) and Abcc3 (Mrp3) on the in vivo elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate.

Vlaming ML, Pala Z, van Esch A, Wagenaar E, van Tellingen O, de Waart DR, Oude Elferink RP, van de Wetering K, Schinkel AH.

Clin Cancer Res. 2008 Dec 15;14(24):8152-60. doi: 10.1158/1078-0432.CCR-08-1609.

19.

Multidrug resistance-associated transporter 2 regulates mucosal inflammation by facilitating the synthesis of hepoxilin A3.

Pazos M, Siccardi D, Mumy KL, Bien JD, Louie S, Shi HN, Gronert K, Mrsny RJ, McCormick BA.

J Immunol. 2008 Dec 1;181(11):8044-52.

20.

Species-dependent transport and modulation properties of human and mouse multidrug resistance protein 2 (MRP2/Mrp2, ABCC2/Abcc2).

Zimmermann C, van de Wetering K, van de Steeg E, Wagenaar E, Vens C, Schinkel AH.

Drug Metab Dispos. 2008 Apr;36(4):631-40. doi: 10.1124/dmd.107.019620. Epub 2008 Jan 7.

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