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CCR5 Is Involved in Interruption of Pregnancy in Mice Infected with Toxoplasma gondii during Early Pregnancy.

Nishimura M, Umeda K, Suwa M, Furuoka H, Nishikawa Y.

Infect Immun. 2017 Aug 18;85(9). pii: e00257-17. doi: 10.1128/IAI.00257-17. Print 2017 Sep.


Knockdown of C-C Chemokine Receptor 5 (CCR5) is Protective Against Cerebral Ischemia and Reperfusion Injury.

Victoria ECG, de Brito Toscano EC, de Sousa Cardoso AC, da Silva DG, de Miranda AS, da Silva Barcelos L, Sugimoto MA, Sousa LP, de Assis Lima IV, de Oliveira ACP, Brant F, Machado FS, Teixeira MM, Teixeira AL, Rachid MA.

Curr Neurovasc Res. 2017;14(2):125-131. doi: 10.2174/1567202614666170313113056.


CCR5 is a suppressor for cortical plasticity and hippocampal learning and memory.

Zhou M, Greenhill S, Huang S, Silva TK, Sano Y, Wu S, Cai Y, Nagaoka Y, Sehgal M, Cai DJ, Lee YS, Fox K, Silva AJ.

Elife. 2016 Dec 20;5. pii: e20985. doi: 10.7554/eLife.20985.


CCR5 ameliorates Japanese encephalitis via dictating the equilibrium of regulatory CD4(+)Foxp3(+) T and IL-17(+)CD4(+) Th17 cells.

Kim JH, Patil AM, Choi JY, Kim SB, Uyangaa E, Hossain FM, Park SY, Lee JH, Eo SK.

J Neuroinflammation. 2016 Jul 20;13(1):223. doi: 10.1186/s12974-016-0656-x.


Cytokine-induced killer cells interact with tumor lysate-pulsed dendritic cells via CCR5 signaling.

Lee HK, Kim YG, Kim JS, Park EJ, Kim B, Park KH, Kang JS, Hong JT, Kim Y, Han SB.

Cancer Lett. 2016 Aug 10;378(2):142-9. doi: 10.1016/j.canlet.2016.05.020. Epub 2016 May 20.


Dual Function of Ccr5 during Langat Virus Encephalitis: Reduction in Neutrophil-Mediated Central Nervous System Inflammation and Increase in T Cell-Mediated Viral Clearance.

Michlmayr D, Bardina SV, Rodriguez CA, Pletnev AG, Lim JK.

J Immunol. 2016 Jun 1;196(11):4622-31. doi: 10.4049/jimmunol.1502452. Epub 2016 Apr 29.


Transient Surface CCR5 Expression by Naive CD8+ T Cells within Inflamed Lymph Nodes Is Dependent on High Endothelial Venule Interaction and Augments Th Cell-Dependent Memory Response.

Askew D, Su CA, Barkauskas DS, Dorand RD, Myers J, Liou R, Nthale J, Huang AY.

J Immunol. 2016 May 1;196(9):3653-64. doi: 10.4049/jimmunol.1501176. Epub 2016 Mar 18.


CCR5 knockout suppresses experimental autoimmune encephalomyelitis in C57BL/6 mice.

Gu SM, Park MH, Yun HM, Han SB, Oh KW, Son DJ, Yun JS, Hong JT.

Oncotarget. 2016 Mar 29;7(13):15382-93. doi: 10.18632/oncotarget.8097.


CCR5 deficiency accelerates lipopolysaccharide-induced astrogliosis, amyloid-beta deposit and impaired memory function.

Hwang CJ, Park MH, Hwang JY, Kim JH, Yun NY, Oh SY, Song JK, Seo HO, Kim YB, Hwang DY, Oh KW, Han SB, Hong JT.

Oncotarget. 2016 Mar 15;7(11):11984-99. doi: 10.18632/oncotarget.7453.


CCR5 limits cortical viral loads during West Nile virus infection of the central nervous system.

Durrant DM, Daniels BP, Pasieka T, Dorsey D, Klein RS.

J Neuroinflammation. 2015 Dec 15;12:233. doi: 10.1186/s12974-015-0447-9.


High-dose cyclophosphamide induces specific tumor immunity with concomitant recruitment of LAMP1/CD107a-expressing CD4-positive T cells into tumor sites.

Naito T, Baba T, Takeda K, Sasaki S, Nakamoto Y, Mukaida N.

Cancer Lett. 2015 Sep 28;366(1):93-9. doi: 10.1016/j.canlet.2015.06.009. Epub 2015 Jun 24.


CCR5 deficiency increased susceptibility to lipopolysaccharide-induced acute renal injury.

Lee DH, Park MH, Hwang CJ, Hwang JY, Yoon HS, Yoon DY, Hong JT.

Arch Toxicol. 2016 May;90(5):1151-62. doi: 10.1007/s00204-015-1530-9. Epub 2015 Jun 9.


CCR5 facilitates endothelial progenitor cell recruitment and promotes the stabilization of atherosclerotic plaques in ApoE-/- mice.

Zhang Z, Dong J, Lobe CG, Gong P, Liu J, Liao L.

Stem Cell Res Ther. 2015 Mar 19;6:36. doi: 10.1186/s13287-015-0026-0.


Role of the chemokine receptor CCR5-dependent host defense system in Neospora caninum infections.

Abe C, Tanaka S, Nishimura M, Ihara F, Xuan X, Nishikawa Y.

Parasit Vectors. 2015 Jan 6;8:5. doi: 10.1186/s13071-014-0620-5.


The chemokine receptor CCR5 plays a role in post-traumatic cartilage loss in mice, but does not affect synovium and bone.

Takebe K, Rai MF, Schmidt EJ, Sandell LJ.

Osteoarthritis Cartilage. 2015 Mar;23(3):454-61. doi: 10.1016/j.joca.2014.12.002. Epub 2014 Dec 9.


CCR5 blockade promotes M2 macrophage activation and improves locomotor recovery after spinal cord injury in mice.

Li F, Cheng B, Cheng J, Wang D, Li H, He X.

Inflammation. 2015 Feb;38(1):126-33. doi: 10.1007/s10753-014-0014-z.


Novel CD8 T cell alloreactivities in CCR5-deficient recipients of class II MHC disparate kidney grafts.

Ishii D, Rosenblum JM, Nozaki T, Schenk AD, Setoguchi K, Su CA, Gorbacheva V, Baldwin WM 3rd, Valujskikh A, Fairchild RL.

J Immunol. 2014 Oct 1;193(7):3816-24. doi: 10.4049/jimmunol.1303256. Epub 2014 Aug 29.


CCR5 controls immune and metabolic functions during Toxoplasma gondii infection.

Bonfá G, Benevides L, Souza Mdo C, Fonseca DM, Mineo TW, Rossi MA, Silva NM, Silva JS, de Barros Cardoso CR.

PLoS One. 2014 Aug 13;9(8):e104736. doi: 10.1371/journal.pone.0104736. eCollection 2014.


CCR5 as a treatment target in pulmonary arterial hypertension.

Amsellem V, Lipskaia L, Abid S, Poupel L, Houssaini A, Quarck R, Marcos E, Mouraret N, Parpaleix A, Bobe R, Gary-Bobo G, Saker M, Dubois-Randé JL, Gladwin MT, Norris KA, Delcroix M, Combadière C, Adnot S.

Circulation. 2014 Sep 9;130(11):880-891. doi: 10.1161/CIRCULATIONAHA.114.010757. Epub 2014 Jul 3.


Loss of CCR5 results in glucose intolerance in diet-induced obese mice.

Kennedy A, Webb CD, Hill AA, Gruen ML, Jackson LG, Hasty AH.

Am J Physiol Endocrinol Metab. 2013 Oct 1;305(7):E897-906. doi: 10.1152/ajpendo.00177.2013. Epub 2013 Aug 13.

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