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Items: 1 to 20 of 348

1.

The oscillation of intracellular Ca2+ influx associated with the circadian expression of Piezo1 and TRPV4 in the bladder urothelium.

Ihara T, Mitsui T, Nakamura Y, Kanda M, Tsuchiya S, Kira S, Nakagomi H, Sawada N, Kamiyama M, Hirayama Y, Shigetomi E, Shinozaki Y, Yoshiyama M, Nakao A, Takeda M, Koizumi S.

Sci Rep. 2018 Apr 9;8(1):5699. doi: 10.1038/s41598-018-23115-w.

2.

CLOCK phosphorylation by AKT regulates its nuclear accumulation and circadian gene expression in peripheral tissues.

Luciano AK, Zhou W, Santana JM, Kyriakides C, Velazquez H, Sessa WC.

J Biol Chem. 2018 Jun 8;293(23):9126-9136. doi: 10.1074/jbc.RA117.000773. Epub 2018 Mar 27.

3.

Female ClockΔ19/Δ19 mice are protected from the development of age-dependent cardiomyopathy.

Alibhai FJ, Reitz CJ, Peppler WT, Basu P, Sheppard P, Choleris E, Bakovic M, Martino TA.

Cardiovasc Res. 2018 Feb 1;114(2):259-271. doi: 10.1093/cvr/cvx185.

PMID:
28927226
4.

Deoxycorticosterone/Salt-Mediated Cardiac Inflammation and Fibrosis Are Dependent on Functional CLOCK Signaling in Male Mice.

Fletcher EK, Morgan J, Kennaway DR, Bienvenu LA, Rickard AJ, Delbridge LMD, Fuller PJ, Clyne CD, Young MJ.

Endocrinology. 2017 Sep 1;158(9):2906-2917. doi: 10.1210/en.2016-1911.

PMID:
28911177
5.

Disrupting the key circadian regulator CLOCK leads to age-dependent cardiovascular disease.

Alibhai FJ, LaMarre J, Reitz CJ, Tsimakouridze EV, Kroetsch JT, Bolz SS, Shulman A, Steinberg S, Burris TP, Oudit GY, Martino TA.

J Mol Cell Cardiol. 2017 Apr;105:24-37. doi: 10.1016/j.yjmcc.2017.01.008. Epub 2017 Feb 20.

6.

Bone Resorption Is Regulated by Circadian Clock in Osteoblasts.

Takarada T, Xu C, Ochi H, Nakazato R, Yamada D, Nakamura S, Kodama A, Shimba S, Mieda M, Fukasawa K, Ozaki K, Iezaki T, Fujikawa K, Yoneda Y, Numano R, Hida A, Tei H, Takeda S, Hinoi E.

J Bone Miner Res. 2017 Apr;32(4):872-881. doi: 10.1002/jbmr.3053. Epub 2017 Mar 3.

7.

Inhibition of G0/G1 Switch 2 Ameliorates Renal Inflammation in Chronic Kidney Disease.

Matsunaga N, Ikeda E, Kakimoto K, Watanabe M, Shindo N, Tsuruta A, Ikeyama H, Hamamura K, Higashi K, Yamashita T, Kondo H, Yoshida Y, Matsuda M, Ogino T, Tokushige K, Itcho K, Furuichi Y, Nakao T, Yasuda K, Doi A, Amamoto T, Aramaki H, Tsuda M, Inoue K, Ojida A, Koyanagi S, Ohdo S.

EBioMedicine. 2016 Nov;13:262-273. doi: 10.1016/j.ebiom.2016.10.008. Epub 2016 Oct 6.

8.

CLOCK regulates mammary epithelial cell growth and differentiation.

Casey T, Crodian J, Suárez-Trujillo A, Erickson E, Weldon B, Crow K, Cummings S, Chen Y, Shamay A, Mabjeesh SJ, Plaut K.

Am J Physiol Regul Integr Comp Physiol. 2016 Dec 1;311(6):R1125-R1134. doi: 10.1152/ajpregu.00032.2016. Epub 2016 Oct 5.

9.

Role of circadian gene Clock during differentiation of mouse pluripotent stem cells.

Lu C, Yang Y, Zhao R, Hua B, Xu C, Yan Z, Sun N, Qian R.

Protein Cell. 2016 Nov;7(11):820-832. doi: 10.1007/s13238-016-0319-9. Epub 2016 Sep 23.

10.

CLOCK modulates survival and acute lung injury in mice with polymicrobial sepsis.

Wang CY, Hsieh MJ, Hsieh IC, Shie SS, Ho MY, Yeh JK, Tsai ML, Yang CH, Hung KC, Wang CC, Wen MS.

Biochem Biophys Res Commun. 2016 Sep 16;478(2):935-41. doi: 10.1016/j.bbrc.2016.08.054. Epub 2016 Aug 9.

PMID:
27520377
11.

The Clock mutation reduces reproductive performance of mice by affecting the implantation capacity: Maternal Clock mutation is not the only factor affecting implantation.

Amano T, Anzai M, Matsumoto K.

Theriogenology. 2016 Oct 15;86(7):1670-84. doi: 10.1016/j.theriogenology.2016.05.027. Epub 2016 Jun 6.

12.

CLOCK promotes 3T3-L1 cell proliferation via Wnt signaling.

Zhu Z, Hua B, Xu L, Yuan G, Li E, Li X, Sun N, Yan Z, Lu C, Qian R.

IUBMB Life. 2016 Jul;68(7):557-68. doi: 10.1002/iub.1512. Epub 2016 May 18.

13.

The Small Molecule Nobiletin Targets the Molecular Oscillator to Enhance Circadian Rhythms and Protect against Metabolic Syndrome.

He B, Nohara K, Park N, Park YS, Guillory B, Zhao Z, Garcia JM, Koike N, Lee CC, Takahashi JS, Yoo SH, Chen Z.

Cell Metab. 2016 Apr 12;23(4):610-21. doi: 10.1016/j.cmet.2016.03.007.

14.

Altered myocardial metabolic adaptation to increased fatty acid availability in cardiomyocyte-specific CLOCK mutant mice.

Peliciari-Garcia RA, Goel M, Aristorenas JA, Shah K, He L, Yang Q, Shalev A, Bailey SM, Prabhu SD, Chatham JC, Gamble KL, Young ME.

Biochim Biophys Acta. 2016 Oct;1861(10):1579-95. doi: 10.1016/j.bbalip.2015.12.012. Epub 2015 Dec 22.

15.

Circadian CLOCK Mediates Activation of Transforming Growth Factor-β Signaling and Renal Fibrosis through Cyclooxygenase 2.

Chen WD, Yeh JK, Peng MT, Shie SS, Lin SL, Yang CH, Chen TH, Hung KC, Wang CC, Hsieh IC, Wen MS, Wang CY.

Am J Pathol. 2015 Dec;185(12):3152-63. doi: 10.1016/j.ajpath.2015.08.003. Epub 2015 Oct 14.

PMID:
26458764
16.

Circadian Gene Clock Regulates Psoriasis-Like Skin Inflammation in Mice.

Ando N, Nakamura Y, Aoki R, Ishimaru K, Ogawa H, Okumura K, Shibata S, Shimada S, Nakao A.

J Invest Dermatol. 2015 Dec;135(12):3001-3008. doi: 10.1038/jid.2015.316. Epub 2015 Aug 20.

17.
18.

Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice.

Sidor MM, Spencer SM, Dzirasa K, Parekh PK, Tye KM, Warden MR, Arey RN, Enwright JF 3rd, Jacobsen JP, Kumar S, Remillard EM, Caron MG, Deisseroth K, McClung CA.

Mol Psychiatry. 2015 Nov;20(11):1406-19. doi: 10.1038/mp.2014.167. Epub 2015 Jan 6. Erratum in: Mol Psychiatry. 2015 Nov;20(11):1479-80.

19.

Overexpression of the Circadian Clock Gene Rev-erbα Affects Murine Bone Mesenchymal Stem Cell Proliferation and Osteogenesis.

He Y, Lin F, Chen Y, Tan Z, Bai D, Zhao Q.

Stem Cells Dev. 2015 May 15;24(10):1194-204. doi: 10.1089/scd.2014.0437. Epub 2015 Jan 26.

20.

The mammalian circadian clock protein period counteracts cryptochrome in phosphorylation dynamics of circadian locomotor output cycles kaput (CLOCK).

Matsumura R, Tsuchiya Y, Tokuda I, Matsuo T, Sato M, Node K, Nishida E, Akashi M.

J Biol Chem. 2014 Nov 14;289(46):32064-72. doi: 10.1074/jbc.M114.578278. Epub 2014 Sep 30.

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