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Items: 1 to 20 of 318

1.

Cyclin-Dependent Kinase 4 Regulates Adult Neural Stem Cell Proliferation and Differentiation in Response to Insulin.

Chirivella L, Kirstein M, Ferrón SR, Domingo-Muelas A, Durupt FC, Acosta-Umanzor C, Cano-Jaimez M, Pérez-Sánchez F, Barbacid M, Ortega S, Burks DJ, Fariñas I.

Stem Cells. 2017 Dec;35(12):2403-2416. doi: 10.1002/stem.2694. Epub 2017 Sep 3.

2.

Melanoma susceptibility as a complex trait: genetic variation controls all stages of tumor progression.

Ferguson B, Ram R, Handoko HY, Mukhopadhyay P, Muller HK, Soyer HP, Morahan G, Walker GJ.

Oncogene. 2015 May 28;34(22):2879-86. doi: 10.1038/onc.2014.227. Epub 2014 Aug 4.

PMID:
25088201
3.

CDK4: A Key Player in the Cell Cycle, Development, and Cancer.

Baker SJ, Reddy EP.

Genes Cancer. 2012 Nov;3(11-12):658-69. doi: 10.1177/1947601913478972.

4.

Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation.

Landsberg J, Kohlmeyer J, Renn M, Bald T, Rogava M, Cron M, Fatho M, Lennerz V, Wölfel T, Hölzel M, Tüting T.

Nature. 2012 Oct 18;490(7420):412-6. doi: 10.1038/nature11538. Epub 2012 Oct 10.

PMID:
23051752
5.

A blueprint for staging of murine melanocytic lesions based on the Cdk4 ( R24C/R24C ) ::Tyr- NRAS ( Q ) ( 61K ) model.

Wurm EM, Lin LL, Ferguson B, Lambie D, Prow TW, Walker GJ, Soyer HP.

Exp Dermatol. 2012 Sep;21(9):676-81. doi: 10.1111/j.1600-0625.2012.01543.x. Epub 2012 Jun 29.

PMID:
22742762
6.

A defect of the INK4-Cdk4 checkpoint and Myc collaborate in blastoid mantle cell lymphoma-like lymphoma formation in mice.

Vincent-Fabert C, Fiancette R, Rouaud P, Baudet C, Truffinet V, Magnone V, Guillaudeau A, Cogné M, Dubus P, Denizot Y.

Am J Pathol. 2012 Apr;180(4):1688-701. doi: 10.1016/j.ajpath.2012.01.004. Epub 2012 Feb 9.

PMID:
22326754
7.

The sole presence of CDK4 is not a solid criterion for discriminating between tumor and healthy pancreatic tissues.

Altirriba J, García A, Sánchez B, Haba L, Altekruse S, Stratmann T, Bombí JA, Mezquita C, Gomis R, Mora C.

Int J Cancer. 2012 Jun 1;130(11):2743-5. doi: 10.1002/ijc.26313. Epub 2011 Aug 29. No abstract available.

8.

Neonatal UVB exposure accelerates melanoma growth and enhances distant metastases in Hgf-Cdk4(R24C) C57BL/6 mice.

Gaffal E, Landsberg J, Bald T, Sporleder A, Kohlmeyer J, Tüting T.

Int J Cancer. 2011 Jul 15;129(2):285-94. doi: 10.1002/ijc.25913. Epub 2011 Apr 21.

9.

Role of Cdk4 in lymphocyte function and allergen response.

Chow YH, Zhu XD, Liu L, Schwartz BR, Huang XZ, Harlan JM, Schnapp LM.

Cell Cycle. 2010 Dec 15;9(24):4922-30. Epub 2010 Dec 15.

10.

Cdk4 regulates recruitment of quiescent beta-cells and ductal epithelial progenitors to reconstitute beta-cell mass.

Lee JH, Jo J, Hardikar AA, Periwal V, Rane SG.

PLoS One. 2010 Jan 13;5(1):e8653. doi: 10.1371/journal.pone.0008653.

11.

A GRFa2/Prop1/stem (GPS) cell niche in the pituitary.

Garcia-Lavandeira M, Quereda V, Flores I, Saez C, Diaz-Rodriguez E, Japon MA, Ryan AK, Blasco MA, Dieguez C, Malumbres M, Alvarez CV.

PLoS One. 2009;4(3):e4815. doi: 10.1371/journal.pone.0004815. Epub 2009 Mar 13.

12.

Murine neonatal melanocytes exhibit a heightened proliferative response to ultraviolet radiation and migrate to the epidermal basal layer.

Walker GJ, Kimlin MG, Hacker E, Ravishankar S, Muller HK, Beermann F, Hayward NK.

J Invest Dermatol. 2009 Jan;129(1):184-93. doi: 10.1038/jid.2008.210. Epub 2008 Jul 17.

13.
14.

Spontaneous and UV radiation-induced multiple metastatic melanomas in Cdk4R24C/R24C/TPras mice.

Hacker E, Muller HK, Irwin N, Gabrielli B, Lincoln D, Pavey S, Powell MB, Malumbres M, Barbacid M, Hayward N, Walker G.

Cancer Res. 2006 Mar 15;66(6):2946-52.

15.

Cyclin-dependent kinase 4 expression is essential for neu-induced breast tumorigenesis.

Reddy HK, Mettus RV, Rane SG, Graña X, Litvin J, Reddy EP.

Cancer Res. 2005 Nov 15;65(22):10174-8.

16.

Evaluation of genetic melanoma vaccines in cdk4-mutant mice provides evidence for immunological tolerance against authochthonous melanomas in the skin.

Steitz J, Büchs S, Tormo D, Ferrer A, Wenzel J, Huber C, Wölfel T, Barbacid M, Malumbres M, Tüting T.

Int J Cancer. 2006 Jan 15;118(2):373-80.

17.
18.

Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence.

Zou X, Ray D, Aziyu A, Christov K, Boiko AD, Gudkov AV, Kiyokawa H.

Genes Dev. 2002 Nov 15;16(22):2923-34.

19.

Cdk4 deficiency inhibits skin tumor development but does not affect normal keratinocyte proliferation.

Rodriguez-Puebla ML, Miliani de Marval PL, LaCava M, Moons DS, Kiyokawa H, Conti CJ.

Am J Pathol. 2002 Aug;161(2):405-11.

20.

Pituitary hypoplasia and lactotroph dysfunction in mice deficient for cyclin-dependent kinase-4.

Moons DS, Jirawatnotai S, Parlow AF, Gibori G, Kineman RD, Kiyokawa H.

Endocrinology. 2002 Aug;143(8):3001-8.

PMID:
12130566

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