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Items: 1 to 20 of 63

1.

Targeted inactivation of copper transporter Atp7b in hepatocytes causes liver steatosis and obesity in mice.

Muchenditsi A, Yang H, Hamilton JP, Koganti L, Housseau F, Aronov L, Fan H, Pierson H, Bhattacharjee A, Murphy R, Sears C, Potter J, Wooton-Kee CR, Lutsenko S.

Am J Physiol Gastrointest Liver Physiol. 2017 Jul 1;313(1):G39-G49. doi: 10.1152/ajpgi.00312.2016. Epub 2017 Apr 20.

2.

Basolateral sorting and transcytosis define the Cu+-regulated translocation of ATP7B to the bile canaliculus.

Lalioti V, Peiró R, Pérez-Berlanga M, Tsuchiya Y, Muñoz A, Villalba T, Sanchez C, Sandoval IV.

J Cell Sci. 2016 Jun 1;129(11):2190-201. doi: 10.1242/jcs.184663. Epub 2016 Mar 31.

3.

Laser ablation inductively coupled plasma mass spectrometry imaging of metals in experimental and clinical Wilson's disease.

Boaru SG, Merle U, Uerlings R, Zimmermann A, Flechtenmacher C, Willheim C, Eder E, Ferenci P, Stremmel W, Weiskirchen R.

J Cell Mol Med. 2015 Apr;19(4):806-14. doi: 10.1111/jcmm.12497. Epub 2015 Feb 20.

4.

Effects of tetrathiomolybdate and penicillamine on brain hydroxyl radical and free copper levels: a microdialysis study in vivo.

Zhang JW, Liu JX, Hou HM, Chen DB, Feng L, Wu C, Wei LT, Li XH.

Biochem Biophys Res Commun. 2015 Feb 27;458(1):82-5. doi: 10.1016/j.bbrc.2015.01.071. Epub 2015 Jan 26.

PMID:
25634697
5.

The discrepancy between the absence of copper deposition and the presence of neuronal damage in the brain of Atp7b(-/-) mice.

Dong Y, Shi SS, Chen S, Ni W, Zhu M, Wu ZY.

Metallomics. 2015 Feb;7(2):283-8. doi: 10.1039/c4mt00242c.

PMID:
25594375
6.

DKWSLLL, a versatile DXXXLL-type signal with distinct roles in the Cu(+)-regulated trafficking of ATP7B.

Lalioti V, Hernandez-Tiedra S, Sandoval IV.

Traffic. 2014 Aug;15(8):839-60. doi: 10.1111/tra.12176. Epub 2014 Jun 24.

7.

Penicillamine increases free copper and enhances oxidative stress in the brain of toxic milk mice.

Chen DB, Feng L, Lin XP, Zhang W, Li FR, Liang XL, Li XH.

PLoS One. 2012;7(5):e37709. doi: 10.1371/journal.pone.0037709. Epub 2012 May 21. Erratum in: PLoS One. 2012;7(8). doi: 10.1371/annotation/e57c1988-71fd-4809-8d84-aff56e60b2c7.

8.

Identification of high-copper-responsive target pathways in Atp7b knockout mouse liver by GSEA on microarray data sets.

He K, Chen Z, Ma Y, Pan Y.

Mamm Genome. 2011 Dec;22(11-12):703-13. doi: 10.1007/s00335-011-9359-x. Epub 2011 Oct 14.

PMID:
21997183
9.

Neuroinflammatory and behavioural changes in the Atp7B mutant mouse model of Wilson's disease.

Terwel D, Löschmann YN, Schmidt HH, Schöler HR, Cantz T, Heneka MT.

J Neurochem. 2011 Jul;118(1):105-12. doi: 10.1111/j.1471-4159.2011.07278.x. Epub 2011 May 19.

10.

Positron emission tomography of copper metabolism in the Atp7b-/- knock-out mouse model of Wilson's disease.

Peng F, Lutsenko S, Sun X, Muzik O.

Mol Imaging Biol. 2012 Feb;14(1):70-8. doi: 10.1007/s11307-011-0476-4.

11.

Atp7b-/- mice as a model for studies of Wilson's disease.

Lutsenko S.

Biochem Soc Trans. 2008 Dec;36(Pt 6):1233-8. doi: 10.1042/BST0361233. Review.

PMID:
19021531
12.

Mitochondrial structure and function in the untreated Jackson toxic milk (tx-j) mouse, a model for Wilson disease.

Roberts EA, Robinson BH, Yang S.

Mol Genet Metab. 2008 Jan;93(1):54-65. Epub 2007 Nov 5.

PMID:
17981064
13.

High copper selectively alters lipid metabolism and cell cycle machinery in the mouse model of Wilson disease.

Huster D, Purnat TD, Burkhead JL, Ralle M, Fiehn O, Stuckert F, Olson NE, Teupser D, Lutsenko S.

J Biol Chem. 2007 Mar 16;282(11):8343-55. Epub 2007 Jan 7.

14.

Metallothionein protein and mRNA in the toxic milk mouse.

Koropatnick J, Cherian MG.

Biochem J. 1994 Nov 15;304(Pt 1):318-9. No abstract available.

15.

In vivo reduction of amyloid-beta by a mutant copper transporter.

Phinney AL, Drisaldi B, Schmidt SD, Lugowski S, Coronado V, Liang Y, Horne P, Yang J, Sekoulidis J, Coomaraswamy J, Chishti MA, Cox DW, Mathews PM, Nixon RA, Carlson GA, St George-Hyslop P, Westaway D.

Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14193-8. Epub 2003 Nov 14.

16.

The Jackson toxic milk mouse as a model for copper loading.

Coronado V, Nanji M, Cox DW.

Mamm Genome. 2001 Oct;12(10):793-5. No abstract available.

PMID:
11668395
17.

The toxic milk mouse is a murine model of Wilson disease.

Theophilos MB, Cox DW, Mercer JF.

Hum Mol Genet. 1996 Oct;5(10):1619-24.

PMID:
8894697
18.

Copper-metallothionein from the toxic milk mutant mouse enhances lipid peroxidation initiated by an organic hydroperoxide.

Stephenson GF, Chan HM, Cherian MG.

Toxicol Appl Pharmacol. 1994 Mar;125(1):90-6.

PMID:
8128500
19.

The toxic milk mouse does have elevated hepatic metallothionein mRNA.

Mercer JF, Paynter JA, Grimes A.

Biochem J. 1994 Nov 15;304 ( Pt 1):317-8. No abstract available.

20.

Structure and function of G protein-coupled receptors.

Strader CD, Fong TM, Tota MR, Underwood D, Dixon RA.

Annu Rev Biochem. 1994;63:101-32. Review. No abstract available.

PMID:
7979235

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