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Items: 1 to 20 of 548

1.

Kinetics of poly(ADP-ribosyl)ation, but not PARP1 itself, determines the cell fate in response to DNA damage in vitro and in vivo.

Schuhwerk H, Bruhn C, Siniuk K, Min W, Erener S, Grigaravicius P, Krüger A, Ferrari E, Zubel T, Lazaro D, Monajembashi S, Kiesow K, Kroll T, Bürkle A, Mangerich A, Hottiger M, Wang ZQ.

Nucleic Acids Res. 2017 Nov 2;45(19):11174-11192. doi: 10.1093/nar/gkx717.

2.

Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells.

Nieborowska-Skorska M, Sullivan K, Dasgupta Y, Podszywalow-Bartnicka P, Hoser G, Maifrede S, Martinez E, Di Marcantonio D, Bolton-Gillespie E, Cramer-Morales K, Lee J, Li M, Slupianek A, Gritsyuk D, Cerny-Reiterer S, Seferynska I, Stoklosa T, Bullinger L, Zhao H, Gorbunova V, Piwocka K, Valent P, Civin CI, Muschen M, Dick JE, Wang JC, Bhatia S, Bhatia R, Eppert K, Minden MD, Sykes SM, Skorski T.

J Clin Invest. 2017 Jun 1;127(6):2392-2406. doi: 10.1172/JCI90825. Epub 2017 May 8.

3.

Poly(ADP-ribose) polymerase-1 regulates microglia mediated decrease of endothelial tight junction integrity.

Mehrabadi AR, Korolainen MA, Odero G, Miller DW, Kauppinen TM.

Neurochem Int. 2017 Sep;108:266-271. doi: 10.1016/j.neuint.2017.04.014. Epub 2017 Apr 28.

PMID:
28461173
4.

Inhibition of Poly-ADP-Ribosylation Fails to Increase Axonal Regeneration or Improve Functional Recovery after Adult Mammalian CNS Injury.

Wang X, Sekine Y, Byrne AB, Cafferty WB, Hammarlund M, Strittmatter SM.

eNeuro. 2016 Dec 26;3(6). pii: ENEURO.0270-16.2016. doi: 10.1523/ENEURO.0270-16.2016. eCollection 2016 Nov-Dec.

5.

Microglial activation induced by the alarmin S100B is regulated by poly(ADP-ribose) polymerase-1.

Xu J, Wang H, Won SJ, Basu J, Kapfhamer D, Swanson RA.

Glia. 2016 Nov;64(11):1869-78. doi: 10.1002/glia.23026. Epub 2016 Jul 22.

6.

Puerarin protects against CCl4-induced liver fibrosis in mice: possible role of PARP-1 inhibition.

Wang S, Shi XL, Feng M, Wang X, Zhang ZH, Zhao X, Han B, Ma HC, Dai B, Ding YT.

Int Immunopharmacol. 2016 Sep;38:238-45. doi: 10.1016/j.intimp.2016.06.008. Epub 2016 Jun 17.

PMID:
27318789
7.

Poly-ADP-ribose polymerase inhibition enhances ischemic and diabetic wound healing by promoting angiogenesis.

Zhou X, Patel D, Sen S, Shanmugam V, Sidawy A, Mishra L, Nguyen BN.

J Vasc Surg. 2017 Apr;65(4):1161-1169. doi: 10.1016/j.jvs.2016.03.407. Epub 2016 Jun 8.

PMID:
27288104
8.

Induction of Poly(ADP-ribose) Polymerase in Mouse Bone Marrow Stromal Cells Exposed to 900 MHz Radiofrequency Fields: Preliminary Observations.

He Q, Sun Y, Zong L, Tong J, Cao Y.

Biomed Res Int. 2016;2016:4918691. doi: 10.1155/2016/4918691. Epub 2016 Apr 14.

9.

Parp1 Deficiency Confers Defects in Chromatin Surveillance and Remodeling During Reprogramming by Nuclear Transfer.

Osada T, Nozaki T, Masutani M.

Curr Protein Pept Sci. 2016;17(7):693-704.

PMID:
27090907
10.

Poly(ADP-ribose) polymerase 1 is a novel target to promote axonal regeneration.

Brochier C, Jones JI, Willis DE, Langley B.

Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15220-5. doi: 10.1073/pnas.1509754112. Epub 2015 Nov 23.

11.

PARP-1 activity is required for the reconsolidation and extinction of contextual fear memory.

Inaba H, Tsukagoshi A, Kida S.

Mol Brain. 2015 Oct 15;8(1):63. doi: 10.1186/s13041-015-0153-7.

12.

Poly(ADP-ribose)polymerase 1 inhibition protects against age-dependent endothelial dysfunction.

Zhang GH, Chao M, Hui LH, Xu DL, Cai WL, Zheng J, Gao M, Zhang MX, Wang J, Lu QH.

Clin Exp Pharmacol Physiol. 2015 Dec;42(12):1266-74. doi: 10.1111/1440-1681.12484.

PMID:
26331430
13.

ARTD1 Suppresses Interleukin 6 Expression by Repressing MLL1-Dependent Histone H3 Trimethylation.

Minotti R, Andersson A, Hottiger MO.

Mol Cell Biol. 2015 Sep;35(18):3189-99. doi: 10.1128/MCB.00196-15. Epub 2015 Jul 6.

14.

PJ-34 inhibits PARP-1 expression and ERK phosphorylation in glioma-conditioned brain microvascular endothelial cells.

Motta C, D'Angeli F, Scalia M, Satriano C, Barbagallo D, Naletova I, Anfuso CD, Lupo G, Spina-Purrello V.

Eur J Pharmacol. 2015 Aug 15;761:55-64. doi: 10.1016/j.ejphar.2015.04.026. Epub 2015 Apr 28.

PMID:
25934569
15.

Poly(ADP) ribose polymerase-1 ablation alters eicosanoid and docosanoid signaling and metabolism in a murine model of contact hypersensitivity.

Kiss B, Szántó M, Szklenár M, Brunyánszki A, Marosvölgyi T, Sárosi E, Remenyik É, Gergely P, Virág L, Decsi T, Rühl R, Bai P.

Mol Med Rep. 2015 Apr;11(4):2861-7. doi: 10.3892/mmr.2014.3044. Epub 2014 Dec 4.

PMID:
25482287
16.

PARP inhibitor, olaparib ameliorates acute lung and kidney injury upon intratracheal administration of LPS in mice.

Kapoor K, Singla E, Sahu B, Naura AS.

Mol Cell Biochem. 2015 Feb;400(1-2):153-62. doi: 10.1007/s11010-014-2271-4. Epub 2014 Nov 18.

PMID:
25404465
17.

PARP-1 regulates epithelial-mesenchymal transition (EMT) in prostate tumorigenesis.

Pu H, Horbinski C, Hensley PJ, Matuszak EA, Atkinson T, Kyprianou N.

Carcinogenesis. 2014 Nov;35(11):2592-601. doi: 10.1093/carcin/bgu183. Epub 2014 Aug 30.

18.

PARP1 enhances inflammatory cytokine expression by alteration of promoter chromatin structure in microglia.

Martínez-Zamudio RI, Ha HC.

Brain Behav. 2014 Jul;4(4):552-65. doi: 10.1002/brb3.239. Epub 2014 Jun 9.

19.

Nucleolar integrity is required for the maintenance of long-term synaptic plasticity.

Allen KD, Gourov AV, Harte C, Gao P, Lee C, Sylvain D, Splett JM, Oxberry WC, van de Nes PS, Troy-Regier MJ, Wolk J, Alarcon JM, Hernández AI.

PLoS One. 2014 Aug 4;9(8):e104364. doi: 10.1371/journal.pone.0104364. eCollection 2014.

20.

Differential localisation of PARP-1 N-terminal fragment in PARP-1(+/+) and PARP-1(-/-) murine cells.

Rajiah IR, Skepper J.

Mol Cells. 2014 Jul;37(7):526-31. doi: 10.14348/molcells.2014.0077. Epub 2014 Jul 31.

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