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Items: 1 to 20 of 29

1.

Lonafarnib is a potential inhibitor for neovascularization.

Sun L, Xie S, Peng G, Wang J, Li Y, Qin J, Zhong D.

PLoS One. 2015 Apr 8;10(4):e0122830. doi: 10.1371/journal.pone.0122830. eCollection 2015.

2.

Caution! Analyze transcripts from conditional knockout alleles.

Yang SH, Bergo MO, Farber E, Qiao X, Fong LG, Young SG.

Transgenic Res. 2009 Jun;18(3):483-9. doi: 10.1007/s11248-008-9237-9. Epub 2008 Dec 18.

3.

Farnesyltransferase regulates neutrophil recruitment and tissue damage in acute pancreatitis.

Merza M, Awla D, Hwaiz R, Rahman M, Appelros S, Abdulla A, Regner S, Thorlacius H.

Pancreas. 2014 Apr;43(3):427-35. doi: 10.1097/MPA.0000000000000041.

PMID:
24622074
4.

Severe hepatocellular disease in mice lacking one or both CaaX prenyltransferases.

Yang SH, Chang SY, Tu Y, Lawson GW, Bergo MO, Fong LG, Young SG.

J Lipid Res. 2012 Jan;53(1):77-86. doi: 10.1194/jlr.M021220. Epub 2011 Oct 28.

5.

Farnesyltransferase haplodeficiency reduces neuropathology and rescues cognitive function in a mouse model of Alzheimer disease.

Cheng S, Cao D, Hottman DA, Yuan L, Bergo MO, Li L.

J Biol Chem. 2013 Dec 13;288(50):35952-60. doi: 10.1074/jbc.M113.503904. Epub 2013 Oct 17.

6.

Targeting isoprenylcysteine methylation ameliorates disease in a mouse model of progeria.

Ibrahim MX, Sayin VI, Akula MK, Liu M, Fong LG, Young SG, Bergo MO.

Science. 2013 Jun 14;340(6138):1330-3. doi: 10.1126/science.1238880. Epub 2013 May 16.

7.

Geranylgeranyltransferase type I (GGTase-I) deficiency hyperactivates macrophages and induces erosive arthritis in mice.

Khan OM, Ibrahim MX, Jonsson IM, Karlsson C, Liu M, Sjogren AK, Olofsson FJ, Brisslert M, Andersson S, Ohlsson C, Hultén LM, Bokarewa M, Bergo MO.

J Clin Invest. 2011 Feb;121(2):628-39. doi: 10.1172/JCI43758. Epub 2011 Jan 25.

8.

Targeting the protein prenyltransferases efficiently reduces tumor development in mice with K-RAS-induced lung cancer.

Liu M, Sjogren AK, Karlsson C, Ibrahim MX, Andersson KM, Olofsson FJ, Wahlstrom AM, Dalin M, Yu H, Chen Z, Yang SH, Young SG, Bergo MO.

Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6471-6. doi: 10.1073/pnas.0908396107. Epub 2010 Mar 22.

9.

Protein farnesyltransferase in embryogenesis, adult homeostasis, and tumor development.

Mijimolle N, Velasco J, Dubus P, Guerra C, Weinbaum CA, Casey PJ, Campuzano V, Barbacid M.

Cancer Cell. 2005 Apr;7(4):313-24.

10.

Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes.

Lee R, Chang SY, Trinh H, Tu Y, White AC, Davies BS, Bergo MO, Fong LG, Lowry WE, Young SG.

Hum Mol Genet. 2010 Apr 15;19(8):1603-17. doi: 10.1093/hmg/ddq036. Epub 2010 Jan 27.

11.

Chromosomal mapping of Adam9, Adam15 and Adam21.

Seldin MF, Hirohata S, Apte SS.

Matrix Biol. 2000 May;19(2):185-7.

PMID:
10842103
12.

Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease.

Tkatchenko TV, Moreno-Rodriguez RA, Conway SJ, Molkentin JD, Markwald RR, Tkatchenko AV.

Physiol Genomics. 2009 Nov 6;39(3):160-8. doi: 10.1152/physiolgenomics.00078.2009. Epub 2009 Sep 1.

13.

High-throughput discovery of novel developmental phenotypes.

Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A; International Mouse Phenotyping Consortium; Jackson Laboratory; Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource Center, MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bućan M, Murray SA.

Nature. 2016 Sep 22;537(7621):508-514. doi: 10.1038/nature19356. Epub 2016 Sep 14. Erratum in: Nature. 2017 Nov 16;551(7680):398.

14.

EUCOMM--the European conditional mouse mutagenesis program.

Friedel RH, Seisenberger C, Kaloff C, Wurst W.

Brief Funct Genomic Proteomic. 2007 Sep;6(3):180-5. Epub 2007 Oct 29.

PMID:
17967808
15.

A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.

Hansen J, Floss T, Van Sloun P, Füchtbauer EM, Vauti F, Arnold HH, Schnütgen F, Wurst W, von Melchner H, Ruiz P.

Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22. Epub 2003 Aug 6.

16.

Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas.

Watahiki A, Waki K, Hayatsu N, Shiraki T, Kondo S, Nakamura M, Sasaki D, Arakawa T, Kawai J, Harbers M, Hayashizaki Y, Carninci P.

Nat Methods. 2004 Dec;1(3):233-9. Epub 2004 Nov 18.

PMID:
15782199
17.

Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray.

Tanaka TS, Jaradat SA, Lim MK, Kargul GJ, Wang X, Grahovac MJ, Pantano S, Sano Y, Piao Y, Nagaraja R, Doi H, Wood WH 3rd, Becker KG, Ko MS.

Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):9127-32.

18.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.

Hansen GM, Markesich DC, Burnett MB, Zhu Q, Dionne KM, Richter LJ, Finnell RH, Sands AT, Zambrowicz BP, Abuin A.

Genome Res. 2008 Oct;18(10):1670-9. doi: 10.1101/gr.078352.108. Epub 2008 Sep 17.

19.

Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.

Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW Jr, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT.

Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14. Epub 2003 Nov 10.

20.

A high-resolution anatomical atlas of the transcriptome in the mouse embryo.

Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A.

PLoS Biol. 2011 Jan 18;9(1):e1000582. doi: 10.1371/journal.pbio.1000582.

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