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Actin-Related Protein 2 (ARP2) and Virus-Induced Filopodia Facilitate Human Respiratory Syncytial Virus Spread.

Mehedi M, McCarty T, Martin SE, Le Nouën C, Buehler E, Chen YC, Smelkinson M, Ganesan S, Fischer ER, Brock LG, Liang B, Munir S, Collins PL, Buchholz UJ.

PLoS Pathog. 2016 Dec 7;12(12):e1006062. doi: 10.1371/journal.ppat.1006062. eCollection 2016 Dec.


Coronin3 regulates gastric cancer invasion and metastasis by interacting with Arp2.

Sun Y, Shang Y, Ren G, Zhou L, Feng B, Li K, Deng L, Liang J, Lu Y, Wang X.

Cancer Biol Ther. 2014 Sep;15(9):1163-73. doi: 10.4161/cbt.29501. Epub 2014 Jun 11.


Phosphorylation of the Arp2 subunit relieves auto-inhibitory interactions for Arp2/3 complex activation.

Narayanan A, LeClaire LL 3rd, Barber DL, Jacobson MP.

PLoS Comput Biol. 2011 Nov;7(11):e1002226. doi: 10.1371/journal.pcbi.1002226. Epub 2011 Nov 10.


Actin-related protein (Arp2) inserts into artificial lipid membranes.

Goldmann WH, Isenberg G.

Cell Biol Int. 2002;26(12):1073-8.


Filamin A, the Arp2/3 complex, and the morphology and function of cortical actin filaments in human melanoma cells.

Flanagan LA, Chou J, Falet H, Neujahr R, Hartwig JH, Stossel TP.

J Cell Biol. 2001 Nov 12;155(4):511-7. Epub 2001 Nov 12.


Nuclear ARP2/3 drives DNA break clustering for homology-directed repair.

Schrank BR, Aparicio T, Li Y, Chang W, Chait BT, Gundersen GG, Gottesman ME, Gautier J.

Nature. 2018 Jul;559(7712):61-66. doi: 10.1038/s41586-018-0237-5. Epub 2018 Jun 20.


Loss of Arp2/3 induces an NF-κB-dependent, nonautonomous effect on chemotactic signaling.

Wu C, Haynes EM, Asokan SB, Simon JM, Sharpless NE, Baldwin AS, Davis IJ, Johnson GL, Bear JE.

J Cell Biol. 2013 Dec 23;203(6):907-16.


Host cell entry by apicomplexa parasites requires actin polymerization in the host cell.

Gonzalez V, Combe A, David V, Malmquist NA, Delorme V, Leroy C, Blazquez S, Ménard R, Tardieux I.

Cell Host Microbe. 2009 Mar 19;5(3):259-72. doi: 10.1016/j.chom.2009.01.011.


Arp2 depletion inhibits sheet-like protrusions but not linear protrusions of fibroblasts and lymphocytes.

Nicholson-Dykstra SM, Higgs HN.

Cell Motil Cytoskeleton. 2008 Nov;65(11):904-22. doi: 10.1002/cm.20312.


Correlation between liver metastasis of the colocalization of actin-related protein 2 and 3 complex and WAVE2 in colorectal carcinoma.

Iwaya K, Oikawa K, Semba S, Tsuchiya B, Mukai Y, Otsubo T, Nagao T, Izumi M, Kuroda M, Domoto H, Mukai K.

Cancer Sci. 2007 Jul;98(7):992-9. Epub 2007 Apr 23.


Coexpression of actin-related protein 2 and Wiskott-Aldrich syndrome family verproline-homologous protein 2 in adenocarcinoma of the lung.

Semba S, Iwaya K, Matsubayashi J, Serizawa H, Kataba H, Hirano T, Kato H, Matsuoka T, Mukai K.

Clin Cancer Res. 2006 Apr 15;12(8):2449-54.


Actin binding to the central domain of WASP/Scar proteins plays a critical role in the activation of the Arp2/3 complex.

Kelly AE, Kranitz H, Dötsch V, Mullins RD.

J Biol Chem. 2006 Apr 14;281(15):10589-97. Epub 2005 Dec 23.


Analysis of the mechanisms of Salmonella-induced actin assembly during invasion of host cells and intracellular replication.

Unsworth KE, Way M, McNiven M, Machesky L, Holden DW.

Cell Microbiol. 2004 Nov;6(11):1041-55.


Inhibiting the Arp2/3 complex limits infection of both intracellular mature vaccinia virus and primate lentiviruses.

Komano J, Miyauchi K, Matsuda Z, Yamamoto N.

Mol Biol Cell. 2004 Dec;15(12):5197-207. Epub 2004 Sep 22.


Importance of free actin filament barbed ends for Arp2/3 complex function in platelets and fibroblasts.

Falet H, Hoffmeister KM, Neujahr R, Italiano JE Jr, Stossel TP, Southwick FS, Hartwig JH.

Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16782-7. Epub 2002 Dec 3.


Reconstitution of actin-based motility of Listeria and Shigella using pure proteins.

Loisel TP, Boujemaa R, Pantaloni D, Carlier MF.

Nature. 1999 Oct 7;401(6753):613-6.


The Arp2/3 complex is essential for the actin-based motility of Listeria monocytogenes.

May RC, Hall ME, Higgs HN, Pollard TD, Chakraborty T, Wehland J, Machesky LM, Sechi AS.

Curr Biol. 1999 Jul 15;9(14):759-62.


Clinical and molecular cytogenetic characterization of four unrelated patients carrying 2p14 microdeletions.

Mathieu ML, Demily C, Chantot-Bastaraud S, Afenjar A, Mignot C, Andrieux J, Gerard M, Catala-Mora J, Jouk PS, Labalme A, Edery P, Sanlaville D, Rossi M.

Am J Med Genet A. 2017 Aug;173(8):2268-2274. doi: 10.1002/ajmg.a.38307. Epub 2017 Jun 9.


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