Format

Send to

Choose Destination
PLoS Comput Biol. 2011 Oct;7(10):e1002231. doi: 10.1371/journal.pcbi.1002231. Epub 2011 Oct 27.

STDP allows fast rate-modulated coding with Poisson-like spike trains.

Author information

1
Department of Electrical and Electronic Engineering, The University of Melbourne, Melbourne, Australia. gilsonm@unimelb.edu.au

Abstract

Spike timing-dependent plasticity (STDP) has been shown to enable single neurons to detect repeatedly presented spatiotemporal spike patterns. This holds even when such patterns are embedded in equally dense random spiking activity, that is, in the absence of external reference times such as a stimulus onset. Here we demonstrate, both analytically and numerically, that STDP can also learn repeating rate-modulated patterns, which have received more experimental evidence, for example, through post-stimulus time histograms (PSTHs). Each input spike train is generated from a rate function using a stochastic sampling mechanism, chosen to be an inhomogeneous Poisson process here. Learning is feasible provided significant covarying rate modulations occur within the typical timescale of STDP (~10-20 ms) for sufficiently many inputs (~100 among 1000 in our simulations), a condition that is met by many experimental PSTHs. Repeated pattern presentations induce spike-time correlations that are captured by STDP. Despite imprecise input spike times and even variable spike counts, a single trained neuron robustly detects the pattern just a few milliseconds after its presentation. Therefore, temporal imprecision and Poisson-like firing variability are not an obstacle to fast temporal coding. STDP provides an appealing mechanism to learn such rate patterns, which, beyond sensory processing, may also be involved in many cognitive tasks.

PMID:
22046113
PMCID:
PMC3203056
DOI:
10.1371/journal.pcbi.1002231
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Public Library of Science Icon for PubMed Central Icon for ModelDB
Loading ...
Support Center