Format

Send to

Choose Destination
Phys Rev Lett. 2003 Jul 11;91(2):028102. Epub 2003 Jul 9.

Saltatory waves in the spike-diffuse-spike model of active dendritic spines.

Author information

1
Department of Mathematical Sciences, Loughborough University, Loughborough LE11 3TU, United Kingdom.

Abstract

In this Letter we present the explicit construction of a saltatory traveling pulse of nonconstant profile in an idealized model of dendritic tissue. Excitable dendritic spine clusters, modeled with integrate-and-fire (IF) units, are connected to a passive dendritic cable at a discrete set of points. The saltatory nature of the wave is directly attributed to the breaking of translation symmetry in the cable. The conditions for propagation failure are presented as a function of cluster separation and IF threshold.

PMID:
12906512
DOI:
10.1103/PhysRevLett.91.028102
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for American Physical Society
Loading ...
Support Center