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Items: 1 to 20 of 295


Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency.

Kong XF, Martinez-Barricarte R, Kennedy J, Mele F, Lazarov T, Deenick EK, Ma CS, Breton G, Lucero KB, Langlais D, Bousfiha A, Aytekin C, Markle J, Trouillet C, Jabot-Hanin F, Arlehamn CSL, Rao G, Picard C, Lasseau T, Latorre D, Hambleton S, Deswarte C, Itan Y, Abarca K, Moraes-Vasconcelos D, Ailal F, Ikinciogullari A, Dogu F, Benhsaien I, Sette A, Abel L, Boisson-Dupuis S, Schröder B, Nussenzweig MC, Liu K, Geissmann F, Tangye SG, Gros P, Sallusto F, Bustamante J, Casanova JL.

Nat Immunol. 2018 Sep;19(9):973-985. doi: 10.1038/s41590-018-0178-z. Epub 2018 Aug 20.


Genetic analysis of cerebral malaria in the mouse model infected with Plasmodium berghei.

Torre S, Langlais D, Gros P.

Mamm Genome. 2018 Jun 19. doi: 10.1007/s00335-018-9752-9. [Epub ahead of print] Review.


Change in Cognition and Other Non-Motor Symptoms With Obstructive Sleep Apnea Treatment in Parkinson Disease.

Kaminska M, Mery VP, Lafontaine AL, Robinson A, Benedetti A, Gros P, Kimoff RJ.

J Clin Sleep Med. 2018 May 15;14(5):819-828. doi: 10.5664/jcsm.7114.


Rocaglates as dual-targeting agents for experimental cerebral malaria.

Langlais D, Cencic R, Moradin N, Kennedy JM, Ayi K, Brown LE, Crandall I, Tarry MJ, Schmeing M, Kain KC, Porco JA Jr, Pelletier J, Gros P.

Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2366-E2375. doi: 10.1073/pnas.1713000115. Epub 2018 Feb 20.


Identification and characterization of a novel chemically induced allele at the planar cell polarity gene Vangl2.

El-Hassan AR, Leung V, Kharfallah F, Guyot MC, Allache R, Gros P, Kibar Z.

Mamm Genome. 2018 Apr;29(3-4):229-244. doi: 10.1007/s00335-017-9721-8. Epub 2017 Oct 24.


CCDC88B is required for pathogenesis of inflammatory bowel disease.

Fodil N, Moradin N, Leung V, Olivier JF, Radovanovic I, Jeyakumar T, Flores Molina M, McFarquhar A, Cayrol R, Bozec D, Shoukry NH, Kubo M, Dimitrieva J, Louis E, Theatre E, Dahan S, Momozawa Y, Georges M, Yeretssian G, Gros P.

Nat Commun. 2017 Oct 13;8(1):932. doi: 10.1038/s41467-017-01381-y.


IRF-8 regulates expansion of myeloid-derived suppressor cells and Foxp3+ regulatory T cells and modulates Th2 immune responses to gastrointestinal nematode infection.

Valanparambil RM, Tam M, Gros PP, Auger JP, Segura M, Gros P, Jardim A, Geary TG, Ozato K, Stevenson MM.

PLoS Pathog. 2017 Oct 2;13(10):e1006647. doi: 10.1371/journal.ppat.1006647. eCollection 2017 Oct.


The mouse Char10 locus regulates severity of pyruvate kinase deficiency and susceptibility to malaria.

Laroque A, Min-Oo G, Tam M, Ponka P, Stevenson MM, Gros P.

PLoS One. 2017 May 18;12(5):e0177818. doi: 10.1371/journal.pone.0177818. eCollection 2017.


Reduced cognitive function in patients with Parkinson disease and obstructive sleep apnea.

Mery VP, Gros P, Lafontaine AL, Robinson A, Benedetti A, Kimoff RJ, Kaminska M.

Neurology. 2017 Mar 21;88(12):1120-1128. doi: 10.1212/WNL.0000000000003738. Epub 2017 Feb 22.


A role for the histone H2A deubiquitinase MYSM1 in maintenance of CD8+ T cells.

Förster M, Boora RK, Petrov JC, Fodil N, Albanese I, Kim J, Gros P, Nijnik A.

Immunology. 2017 May;151(1):110-121. doi: 10.1111/imm.12710. Epub 2017 Feb 20.


Genetics of Infectious and Inflammatory Diseases: Overlapping Discoveries from Association and Exome-Sequencing Studies.

Langlais D, Fodil N, Gros P.

Annu Rev Immunol. 2017 Apr 26;35:1-30. doi: 10.1146/annurev-immunol-051116-052442. Epub 2016 Dec 1. Review.


USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation.

Torre S, Polyak MJ, Langlais D, Fodil N, Kennedy JM, Radovanovic I, Berghout J, Leiva-Torres GA, Krawczyk CM, Ilangumaran S, Mossman K, Liang C, Knobeloch KP, Healy LM, Antel J, Arbour N, Prat A, Majewski J, Lathrop M, Vidal SM, Gros P.

Nat Immunol. 2017 Jan;18(1):54-63. doi: 10.1038/ni.3581. Epub 2016 Oct 10. Erratum in: Nat Immunol. 2016 Nov 16;17 (12 ):1479.


Cysteamine broadly improves the anti-plasmodial activity of artemisinins against murine blood stage and cerebral malaria.

Moradin N, Torre S, Gauthier S, Tam M, Hawari J, Vandercruyssen K, De Spiegeleer B, Fortin A, Stevenson MM, Gros P.

Malar J. 2016 May 6;15(1):260. doi: 10.1186/s12936-016-1317-3.


The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation.

Langlais D, Barreiro LB, Gros P.

J Exp Med. 2016 Apr 4;213(4):585-603. doi: 10.1084/jem.20151764. Epub 2016 Mar 21.


Mapping hyper-susceptibility to colitis-associated colorectal cancer in FVB/NJ mice.

Van Der Kraak L, Langlais D, Jothy S, Beauchemin N, Gros P.

Mamm Genome. 2016 Jun;27(5-6):213-24. doi: 10.1007/s00335-016-9625-z. Epub 2016 Mar 15.


Primary Immunodeficiencies and Inflammatory Disease: A Growing Genetic Intersection.

Fodil N, Langlais D, Gros P.

Trends Immunol. 2016 Feb;37(2):126-140. doi: 10.1016/ Epub 2016 Jan 12. Review.


Repression of p53-target gene Bbc3/PUMA by MYSM1 is essential for the survival of hematopoietic multipotent progenitors and contributes to stem cell maintenance.

Belle JI, Petrov JC, Langlais D, Robert F, Cencic R, Shen S, Pelletier J, Gros P, Nijnik A.

Cell Death Differ. 2016 May;23(5):759-75. doi: 10.1038/cdd.2015.140. Epub 2016 Jan 15.


Modulation of Malaria Phenotypes by Pyruvate Kinase (PKLR) Variants in a Thai Population.

van Bruggen R, Gualtieri C, Iliescu A, Louicharoen Cheepsunthorn C, Mungkalasut P, Trape JF, Modiano D, Sirima BS, Singhasivanon P, Lathrop M, Sakuntabhai A, Bureau JF, Gros P.

PLoS One. 2015 Dec 14;10(12):e0144555. doi: 10.1371/journal.pone.0144555. eCollection 2015.


Colitis-associated colon cancer: Is it in your genes?

Van Der Kraak L, Gros P, Beauchemin N.

World J Gastroenterol. 2015 Nov 7;21(41):11688-99. doi: 10.3748/wjg.v21.i41.11688. Review.


Diagnosis of Obstructive Sleep Apnea in Parkinson's Disease Patients: Is Unattended Portable Monitoring a Suitable Tool?

Gros P, Mery VP, Lafontaine AL, Robinson A, Benedetti A, Kimoff RJ, Kaminska M.

Parkinsons Dis. 2015;2015:258418. doi: 10.1155/2015/258418. Epub 2015 Oct 13.

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