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Items: 1 to 20 of 56

1.

Biomechanical interplay between anisotropic re-organization of cells and the surrounding matrix underlies transition to invasive cancer spread.

Kim DH, Ewald AJ, Park J, Kshitiz, Kwak M, Gray RS, Su CY, Seo J, An SS, Levchenko A.

Sci Rep. 2018 Sep 21;8(1):14210. doi: 10.1038/s41598-018-32010-3.

2.

Desmin Phosphorylation Triggers Preamyloid Oligomers Formation and Myocyte Dysfunction in Acquired Heart Failure.

Rainer PP, Dong P, Sorge M, Fert-Bober J, Holewinski RJ, Wang Y, Foss CA, An SS, Baracca A, Solaini G, Glabe CG, Pomper MG, Van Eyk JE, Tomaselli GF, Paolocci N, Agnetti G.

Circ Res. 2018 May 11;122(10):e75-e83. doi: 10.1161/CIRCRESAHA.117.312082. Epub 2018 Feb 26.

PMID:
29483093
3.

TGFβ1 reinforces arterial aging in the vascular smooth muscle cell through a long-range regulation of the cytoskeletal stiffness.

Zhu W, Kim BC, Wang M, Huang J, Isak A, Bexiga NM, Monticone R, Ha T, Lakatta EG, An SS.

Sci Rep. 2018 Feb 8;8(1):2668. doi: 10.1038/s41598-018-20763-w.

4.

Functional dissection of astrocyte-secreted proteins: Implications in brain health and diseases.

Jha MK, Kim JH, Song GJ, Lee WH, Lee IK, Lee HW, An SSA, Kim S, Suk K.

Prog Neurobiol. 2018 Mar;162:37-69. doi: 10.1016/j.pneurobio.2017.12.003. Epub 2017 Dec 13. Review.

PMID:
29247683
5.

Biased signaling of the proton-sensing receptor OGR1 by benzodiazepines.

Pera T, Deshpande DA, Ippolito M, Wang B, Gavrila A, Michael JV, Nayak AP, Tompkins E, Farrell E, Kroeze WK, Roth BL, Panettieri RA Jr, Benovic JL, An SS, Dulin NO, Penn RB.

FASEB J. 2018 Feb;32(2):862-874. doi: 10.1096/fj.201700555R. Epub 2018 Jan 4.

PMID:
29042451
6.

TGF-β1 Evokes Human Airway Smooth Muscle Cell Shortening and Hyperresponsiveness via Smad3.

Ojiaku CA, Cao G, Zhu W, Yoo EJ, Shumyatcher M, Himes BE, An SS, Panettieri RA Jr.

Am J Respir Cell Mol Biol. 2018 May;58(5):575-584. doi: 10.1165/rcmb.2017-0247OC.

PMID:
28984468
7.

12 facilitates shortening in human airway smooth muscle by modulating phosphoinositide 3-kinase-mediated activation in a RhoA-dependent manner.

Yoo EJ, Cao G, Koziol-White CJ, Ojiaku CA, Sunder K, Jude JA, Michael JV, Lam H, Pushkarsky I, Damoiseaux R, Di Carlo D, Ahn K, An SS, Penn RB, Panettieri RA Jr.

Br J Pharmacol. 2017 Dec;174(23):4383-4395. doi: 10.1111/bph.14040. Epub 2017 Nov 12.

8.

Opsin 3 and 4 mediate light-induced pulmonary vasorelaxation that is potentiated by G protein-coupled receptor kinase 2 inhibition.

Barreto Ortiz S, Hori D, Nomura Y, Yun X, Jiang H, Yong H, Chen J, Paek S, Pandey D, Sikka G, Bhatta A, Gillard A, Steppan J, Kim JH, Adachi H, Barodka VM, Romer L, An SS, Shimoda LA, Santhanam L, Berkowitz DE.

Am J Physiol Lung Cell Mol Physiol. 2018 Jan 1;314(1):L93-L106. doi: 10.1152/ajplung.00091.2017. Epub 2017 Sep 7.

9.

AIM1 is an actin-binding protein that suppresses cell migration and micrometastatic dissemination.

Haffner MC, Esopi DM, Chaux A, Gürel M, Ghosh S, Vaghasia AM, Tsai H, Kim K, Castagna N, Lam H, Hicks J, Wyhs N, Biswal Shinohara D, Hurley PJ, Simons BW, Schaeffer EM, Lotan TL, Isaacs WB, Netto GJ, De Marzo AM, Nelson WG, An SS, Yegnasubramanian S.

Nat Commun. 2017 Jul 26;8(1):142. doi: 10.1038/s41467-017-00084-8.

10.

Cigarette smoke disrupts monolayer integrity by altering epithelial cell-cell adhesion and cortical tension.

Nishida K, Brune KA, Putcha N, Mandke P, O'Neal WK, Shade D, Srivastava V, Wang M, Lam H, An SS, Drummond MB, Hansel NN, Robinson DN, Sidhaye VK.

Am J Physiol Lung Cell Mol Physiol. 2017 Sep 1;313(3):L581-L591. doi: 10.1152/ajplung.00074.2017. Epub 2017 Jun 22.

11.

TWIST1-WDR5-Hottip Regulates Hoxa9 Chromatin to Facilitate Prostate Cancer Metastasis.

Malek R, Gajula RP, Williams RD, Nghiem B, Simons BW, Nugent K, Wang H, Taparra K, Lemtiri-Chlieh G, Yoon AR, True L, An SS, DeWeese TL, Ross AE, Schaeffer EM, Pienta KJ, Hurley PJ, Morrissey C, Tran PT.

Cancer Res. 2017 Jun 15;77(12):3181-3193. doi: 10.1158/0008-5472.CAN-16-2797. Epub 2017 May 8.

12.

Role of differentially expressed microRNA-139-5p in the regulation of phenotypic internal anal sphincter smooth muscle tone.

Singh J, Mohanty I, Addya S, Phillips B, Mee Yong H, An SS, Penn RB, Rattan S.

Sci Rep. 2017 May 3;7(1):1477. doi: 10.1038/s41598-017-01550-5.

13.

Taste and smell GPCRs in the lung: Evidence for a previously unrecognized widespread chemosensory system.

An SS, Liggett SB.

Cell Signal. 2018 Jan;41:82-88. doi: 10.1016/j.cellsig.2017.02.002. Epub 2017 Feb 4. Review.

14.

Tissue Transglutaminase Modulates Vascular Stiffness and Function Through Crosslinking-Dependent and Crosslinking-Independent Functions.

Steppan J, Bergman Y, Viegas K, Armstrong D, Tan S, Wang H, Melucci S, Hori D, Park SY, Barreto SF, Isak A, Jandu S, Flavahan N, Butlin M, An SS, Avolio A, Berkowitz DE, Halushka MK, Santhanam L.

J Am Heart Assoc. 2017 Feb 3;6(2). pii: e004161. doi: 10.1161/JAHA.116.004161.

15.

Coupling of Airway Smooth Muscle Bitter Taste Receptors to Intracellular Signaling and Relaxation Is via Gαi1,2,3.

Kim D, Woo JA, Geffken E, An SS, Liggett SB.

Am J Respir Cell Mol Biol. 2017 Jun;56(6):762-771. doi: 10.1165/rcmb.2016-0373OC.

16.

Impaired Relaxation of Airway Smooth Muscle in Mice Lacking the Actin-Binding Protein Gelsolin.

Mikami M, Zhang Y, Danielsson J, Joell T, Yong HM, Townsend E, Khurana S, An SS, Emala CW.

Am J Respir Cell Mol Biol. 2017 May;56(5):628-636. doi: 10.1165/rcmb.2016-0292OC.

17.

Defining an olfactory receptor function in airway smooth muscle cells.

Aisenberg WH, Huang J, Zhu W, Rajkumar P, Cruz R, Santhanam L, Natarajan N, Yong HM, De Santiago B, Oh JJ, Yoon AR, Panettieri RA, Homann O, Sullivan JK, Liggett SB, Pluznick JL, An SS.

Sci Rep. 2016 Dec 1;6:38231. doi: 10.1038/srep38231.

18.

β2-Adrenergic Receptors Chaperone Trapped Bitter Taste Receptor 14 to the Cell Surface as a Heterodimer and Exert Unidirectional Desensitization of Taste Receptor Function.

Kim D, Pauer SH, Yong HM, An SS, Liggett SB.

J Biol Chem. 2016 Aug 19;291(34):17616-28. doi: 10.1074/jbc.M116.722736. Epub 2016 Jun 24.

19.

Directed migration of cancer cells guided by the graded texture of the underlying matrix.

Park J, Kim DH, Kim HN, Wang CJ, Kwak MK, Hur E, Suh KY, An SS, Levchenko A.

Nat Mater. 2016 Jul;15(7):792-801. doi: 10.1038/nmat4586. Epub 2016 Mar 14.

20.

An inflammation-independent contraction mechanophenotype of airway smooth muscle in asthma.

An SS, Mitzner W, Tang WY, Ahn K, Yoon AR, Huang J, Kilic O, Yong HM, Fahey JW, Kumar S, Biswal S, Holgate ST, Panettieri RA Jr, Solway J, Liggett SB.

J Allergy Clin Immunol. 2016 Jul;138(1):294-297.e4. doi: 10.1016/j.jaci.2015.12.1315. Epub 2016 Feb 28. No abstract available.

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