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Items: 106


The Overlap of Lung Tissue Transcriptome of Smoke Exposed Mice with Human Smoking and COPD.

Obeidat M, Dvorkin-Gheva A, Li X, Bossé Y, Brandsma CA, Nickle DC, Hansbro PM, Faner R, Agusti A, Paré PD, Stampfli MR, Sin DD.

Sci Rep. 2018 Aug 8;8(1):11881. doi: 10.1038/s41598-018-30313-z.


The immune system as a victim and aggressor in chronic obstructive pulmonary disease.

McGrath JJC, Stampfli MR.

J Thorac Dis. 2018 Jun;10(Suppl 17):S2011-S2017. doi: 10.21037/jtd.2018.05.63. No abstract available.


Does Compromised Immune Exclusion Drive Inflammatory Processes in Chronic Obstructive Pulmonary Disease?

Stampfli MR, Churg AM.

Am J Respir Cell Mol Biol. 2018 Jun;58(6):671-672. doi: 10.1165/rcmb.2018-0039ED. No abstract available.


Female Sex and Gender in Lung/Sleep Health and Disease. Increased Understanding of Basic Biological, Pathophysiological, and Behavioral Mechanisms Leading to Better Health for Female Patients with Lung Disease.

Han MK, Arteaga-Solis E, Blenis J, Bourjeily G, Clegg DJ, DeMeo D, Duffy J, Gaston B, Heller NM, Hemnes A, Henske EP, Jain R, Lahm T, Lancaster LH, Lee J, Legato MJ, McKee S, Mehra R, Morris A, Prakash YS, Stampfli MR, Gopal-Srivastava R, Laposky AD, Punturieri A, Reineck L, Tigno X, Clayton J.

Am J Respir Crit Care Med. 2018 Oct 1;198(7):850-858. doi: 10.1164/rccm.201801-0168WS.


Identification of microRNAs as potential markers of ovarian toxicity.

Furlong HC, Stämpfli MR, Gannon AM, Foster WG.

J Appl Toxicol. 2018 May;38(5):744-752. doi: 10.1002/jat.3583. Epub 2018 Jan 29.


Identification of Drug Candidates to Suppress Cigarette Smoke-induced Inflammation via Connectivity Map Analyses.

Vanderstocken G, Dvorkin-Gheva A, Shen P, Brandsma CA, Obeidat M, Bossé Y, Hassell JA, Stampfli MR.

Am J Respir Cell Mol Biol. 2018 Jun;58(6):727-735. doi: 10.1165/rcmb.2017-0202OC.


Novel Role for Interleukin-17 in Enhancing Type 1 Helper T Cell Immunity in the Female Genital Tract following Mucosal Herpes Simplex Virus 2 Vaccination.

Bagri P, Anipindi VC, Nguyen PV, Vitali D, Stämpfli MR, Kaushic C.

J Virol. 2017 Nov 14;91(23). pii: e01234-17. doi: 10.1128/JVI.01234-17. Print 2017 Dec 1.


Streptococcus pneumoniae Colonization Is Required To Alter the Nasal Microbiota in Cigarette Smoke-Exposed Mice.

Shen P, Whelan FJ, Schenck LP, McGrath JJC, Vanderstocken G, Bowdish DME, Surette MG, Stämpfli MR.

Infect Immun. 2017 Sep 20;85(10). pii: e00434-17. doi: 10.1128/IAI.00434-17. Print 2017 Oct.


Targeting Interleukin-17 signalling in cigarette smoke-induced lung disease: Mechanistic concepts and therapeutic opportunities.

Roos AB, Stampfli MR.

Pharmacol Ther. 2017 Oct;178:123-131. doi: 10.1016/j.pharmthera.2017.04.001. Epub 2017 Apr 21. Review.


Increased IL-17RA and IL-17RC in End-Stage COPD and the Contribution to Mast Cell Secretion of FGF-2 and VEGF.

Roos AB, Mori M, Gura HK, Lorentz A, Bjermer L, Hoffmann HJ, Erjefält JS, Stampfli MR.

Respir Res. 2017 Mar 15;18(1):48. doi: 10.1186/s12931-017-0534-9.


Role of BAFF in pulmonary autoantibody responses induced by chronic cigarette smoke exposure in mice.

Morissette MC, Gao Y, Shen P, Thayaparan D, Bérubé JC, Paré PD, Brandsma CA, Hao K, Bossé Y, Ettinger R, Herbst R, Humbles AA, Kolbeck R, Zhong N, Chen R, Stämpfli MR.

Physiol Rep. 2016 Dec;4(24). pii: e13057. doi: 10.14814/phy2.13057.


Total particulate matter concentration skews cigarette smoke's gene expression profile.

Dvorkin-Gheva A, Vanderstocken G, Yildirim AÖ, Brandsma CA, Obeidat M, Bossé Y, Hassell JA, Stampfli MR.

ERJ Open Res. 2016 Nov 9;2(4). pii: 00029-2016. eCollection 2016 Oct.


Induction of pulmonary antibodies against oxidized lipids in mice exposed to cigarette smoke.

Thayaparan D, Shen P, Stämpfli MR, Morissette MC.

Respir Res. 2016 Aug 4;17(1):97. doi: 10.1186/s12931-016-0416-6.


Correction: Estradiol Enhances CD4+ T-Cell Anti-Viral Immunity by Priming Vaginal DCs to Induce Th17 Responses via an IL-1-Dependent Pathway.

Anipindi VC, Bagri P, Roth K, Dizzell SE, Nguyen PV, Shaler CR, Chu DK, Jiménez-Saiz R, Liang H, Swift SL, Nazli A, Kafka JK, Bramson J, Xing Z, Jordana M, Wan Y, Snider DP, Stampfli MR, Kaushic C.

PLoS Pathog. 2016 Jun 8;12(6):e1005706. doi: 10.1371/journal.ppat.1005706. eCollection 2016 Jun.


Estradiol Enhances CD4+ T-Cell Anti-Viral Immunity by Priming Vaginal DCs to Induce Th17 Responses via an IL-1-Dependent Pathway.

Anipindi VC, Bagri P, Roth K, Dizzell SE, Nguyen PV, Shaler CR, Chu DK, Jiménez-Saiz R, Liang H, Swift S, Nazli A, Kafka JK, Bramson J, Xing Z, Jordana M, Wan Y, Snider DP, Stampfli MR, Kaushic C.

PLoS Pathog. 2016 May 5;12(5):e1005589. doi: 10.1371/journal.ppat.1005589. eCollection 2016 May. Erratum in: PLoS Pathog. 2016 Jun;12(6):e1005706.


Hydroxychloroquine attenuates cigarette smoke induced autophagic signaling in the mouse ovary.

Furlong HC, Wessels JM, Guerra MT, Stämpfli MR, Foster WG.

Reprod Toxicol. 2016 Jun;61:105-13. doi: 10.1016/j.reprotox.2016.03.044. Epub 2016 Mar 29.


Cigarette Smoke Attenuates the Nasal Host Response to Streptococcus pneumoniae and Predisposes to Invasive Pneumococcal Disease in Mice.

Shen P, Morissette MC, Vanderstocken G, Gao Y, Hassan M, Roos A, Thayaparan D, Merlano M, Dorrington MG, Nikota JK, Bauer CMT, Kwiecien JM, Labiris R, Bowdish DME, Stevenson CS, Stämpfli MR.

Infect Immun. 2016 Apr 22;84(5):1536-1547. doi: 10.1128/IAI.01504-15. Print 2016 May.


Small airway epithelial-C/EBPβ is increased in patients with advanced COPD.

Mori M, Bjermer L, Erjefält JS, Stampfli MR, Roos AB.

Respir Res. 2015 Oct 29;16:133. doi: 10.1186/s12931-015-0297-0.


Cigarette smoke exposure triggers the autophagic cascade via activation of the AMPK pathway in mice.

Furlong HC, Stämpfli MR, Gannon AM, Foster WG.

Biol Reprod. 2015 Oct;93(4):93. doi: 10.1095/biolreprod.115.132183. Epub 2015 Sep 16.


Disruption of pulmonary lipid homeostasis drives cigarette smoke-induced lung inflammation in mice.

Morissette MC, Shen P, Thayaparan D, Stämpfli MR.

Eur Respir J. 2015 Nov;46(5):1451-60. doi: 10.1183/09031936.00216914. Epub 2015 Jun 25.


IL-17A and the Promotion of Neutrophilia in Acute Exacerbation of Chronic Obstructive Pulmonary Disease.

Roos AB, Sethi S, Nikota J, Wrona CT, Dorrington MG, Sandén C, Bauer CM, Shen P, Bowdish D, Stevenson CS, Erjefält JS, Stampfli MR.

Am J Respir Crit Care Med. 2015 Aug 15;192(4):428-37. doi: 10.1164/rccm.201409-1689OC.


IL-17A Is Elevated in End-Stage Chronic Obstructive Pulmonary Disease and Contributes to Cigarette Smoke-induced Lymphoid Neogenesis.

Roos AB, Sandén C, Mori M, Bjermer L, Stampfli MR, Erjefält JS.

Am J Respir Crit Care Med. 2015 Jun 1;191(11):1232-41. doi: 10.1164/rccm.201410-1861OC.


Influenza promotes collagen deposition via αvβ6 integrin-mediated transforming growth factor β activation.

Jolly L, Stavrou A, Vanderstoken G, Meliopoulos VA, Habgood A, Tatler AL, Porte J, Knox A, Weinreb P, Violette S, Hussell T, Kolb M, Stampfli MR, Schultz-Cherry S, Jenkins G.

J Biol Chem. 2014 Dec 19;289(51):35246-63. doi: 10.1074/jbc.M114.582262. Epub 2014 Oct 22.


Cigarette smoke primes the pulmonary environment to IL-1α/CXCR-2-dependent nontypeable Haemophilus influenzae-exacerbated neutrophilia in mice.

Nikota JK, Shen P, Morissette MC, Fernandes K, Roos A, Chu DK, Barra NG, Iwakura Y, Kolbeck R, Humbles AA, Stampfli MR.

J Immunol. 2014 Sep 15;193(6):3134-45. doi: 10.4049/jimmunol.1302412. Epub 2014 Aug 4.


Impacts of peroxisome proliferator-activated receptor-γ activation on cigarette smoke-induced exacerbated response to bacteria.

Morissette MC, Shen P, Thayaparan D, Stämpfli MR.

Eur Respir J. 2015 Jan;45(1):191-200. doi: 10.1183/09031936.00004314. Epub 2014 Jul 17.


Persistence of pulmonary tertiary lymphoid tissues and anti-nuclear antibodies following cessation of cigarette smoke exposure.

Morissette MC, Jobse BN, Thayaparan D, Nikota JK, Shen P, Labiris NR, Kolbeck R, Nair P, Humbles AA, Stämpfli MR.

Respir Res. 2014 Apr 22;15:49. doi: 10.1186/1465-9921-15-49.


Impact of inflammation, emphysema, and smoking cessation on V/Q in mouse models of lung obstruction.

Jobse BN, McCurry CA, Morissette MC, Rhem RG, Stämpfli MR, Labiris NR.

Respir Res. 2014 Apr 14;15:42. doi: 10.1186/1465-9921-15-42.


Impact of cigarette smoke on the human and mouse lungs: a gene-expression comparison study.

Morissette MC, Lamontagne M, Bérubé JC, Gaschler G, Williams A, Yauk C, Couture C, Laviolette M, Hogg JC, Timens W, Halappanavar S, Stampfli MR, Bossé Y.

PLoS One. 2014 Mar 24;9(3):e92498. doi: 10.1371/journal.pone.0092498. eCollection 2014.


A GM-CSF/IL-33 pathway facilitates allergic airway responses to sub-threshold house dust mite exposure.

Llop-Guevara A, Chu DK, Walker TD, Goncharova S, Fattouh R, Silver JS, Moore CL, Xie JL, O'Byrne PM, Coyle AJ, Kolbeck R, Humbles AA, Stämpfli MR, Jordana M.

PLoS One. 2014 Feb 14;9(2):e88714. doi: 10.1371/journal.pone.0088714. eCollection 2014.


Alterations in skeletal muscle cell homeostasis in a mouse model of cigarette smoke exposure.

Caron MA, Morissette MC, Thériault ME, Nikota JK, Stämpfli MR, Debigaré R.

PLoS One. 2013 Jun 14;8(6):e66433. doi: 10.1371/journal.pone.0066433. Print 2013.


Continuous and discontinuous cigarette smoke exposure differentially affects protective Th1 immunity against pulmonary tuberculosis.

Shaler CR, Horvath CN, McCormick S, Jeyanathan M, Khera A, Zganiacz A, Kasinska J, Stampfli MR, Xing Z.

PLoS One. 2013;8(3):e59185. doi: 10.1371/journal.pone.0059185. Epub 2013 Mar 19.


Asthma associated with incontinentia pigmenti and Fanconi anemia: variable airflow limitation without cellular bronchitis.

Dasgupta A, Sanaee MS, Bauer CMT, Botelho FM, Arnold DM, Stampfli MR, Nair P.

Chest. 2013 Mar;143(3):856-858. doi: 10.1378/chest.12-0859.


Detection of lung dysfunction using ventilation and perfusion SPECT in a mouse model of chronic cigarette smoke exposure.

Jobse BN, Rhem RG, Wang IQ, Counter WB, Stämpfli MR, Labiris NR.

J Nucl Med. 2013 Apr;54(4):616-23. doi: 10.2967/jnumed.112.111419. Epub 2013 Feb 8.


Cigarette smoke exposure elicits increased autophagy and dysregulation of mitochondrial dynamics in murine granulosa cells.

Gannon AM, Stämpfli MR, Foster WG.

Biol Reprod. 2013 Mar 14;88(3):63. doi: 10.1095/biolreprod.112.106617. Print 2013 Mar.


The influence of cigarette smoking on viral infections: translating bench science to impact COPD pathogenesis and acute exacerbations of COPD clinically.

Bauer CMT, Morissette MC, Stämpfli MR.

Chest. 2013 Jan;143(1):196-206. doi: 10.1378/chest.12-0930. Review.


Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1α-dependent in mice.

Botelho FM, Nikota JK, Bauer CM, Morissette MC, Iwakura Y, Kolbeck R, Finch D, Humbles AA, Stämpfli MR.

Respir Res. 2012 Sep 19;13:81. doi: 10.1186/1465-9921-13-81.


Cigarette smoke-induced inflammation and respiratory host defense: Insights from animal models.

Nikota JK, Stämpfli MR.

Pulm Pharmacol Ther. 2012 Aug;25(4):257-62. doi: 10.1016/j.pupt.2012.05.005. Epub 2012 May 24. Review.


Cigarette smoke and platelet-activating factor receptor dependent adhesion of Streptococcus pneumoniae to lower airway cells.

Grigg J, Walters H, Sohal SS, Wood-Baker R, Reid DW, Xu CB, Edvinsson L, Morissette MC, Stämpfli MR, Kirwan M, Koh L, Suri R, Mushtaq N.

Thorax. 2012 Oct;67(10):908-13. doi: 10.1136/thoraxjnl-2011-200835. Epub 2012 May 1.


Shifting of immune responsiveness to house dust mite by influenza A infection: genomic insights.

Al-Garawi A, Husain M, Ilieva D, Humbles AA, Kolbeck R, Stampfli MR, O'Byrne PM, Coyle AJ, Jordana M.

J Immunol. 2012 Jan 15;188(2):832-43. doi: 10.4049/jimmunol.1102349. Epub 2011 Dec 14.


IL-1α/IL-1R1 expression in chronic obstructive pulmonary disease and mechanistic relevance to smoke-induced neutrophilia in mice.

Botelho FM, Bauer CM, Finch D, Nikota JK, Zavitz CC, Kelly A, Lambert KN, Piper S, Foster ML, Goldring JJ, Wedzicha JA, Bassett J, Bramson J, Iwakura Y, Sleeman M, Kolbeck R, Coyle AJ, Humbles AA, Stämpfli MR.

PLoS One. 2011;6(12):e28457. doi: 10.1371/journal.pone.0028457. Epub 2011 Dec 6.


Cigarette smoke exposure leads to follicle loss via an alternative ovarian cell death pathway in a mouse model.

Gannon AM, Stämpfli MR, Foster WG.

Toxicol Sci. 2012 Jan;125(1):274-84. doi: 10.1093/toxsci/kfr279. Epub 2011 Oct 14.


Influenza A facilitates sensitization to house dust mite in infant mice leading to an asthma phenotype in adulthood.

Al-Garawi A, Fattouh R, Botelho F, Walker TD, Goncharova S, Moore CL, Mori M, Erjefalt JS, Chu DK, Humbles AA, Kolbeck R, Stampfli MR, O'Byrne PM, Coyle AJ, Jordana M.

Mucosal Immunol. 2011 Nov;4(6):682-94. doi: 10.1038/mi.2011.35. Epub 2011 Aug 31.


Cigarette smoke exposure aggravates air space enlargement and alveolar cell apoptosis in Smad3 knockout mice.

Farkas L, Farkas D, Warburton D, Gauldie J, Shi W, Stampfli MR, Voelkel NF, Kolb M.

Am J Physiol Lung Cell Mol Physiol. 2011 Oct;301(4):L391-401. doi: 10.1152/ajplung.00369.2010. Epub 2011 Jul 8.


Lung epithelial CCAAT/enhancer-binding protein-β is necessary for the integrity of inflammatory responses to cigarette smoke.

Didon L, Barton JL, Roos AB, Gaschler GJ, Bauer CM, Berg T, Stämpfli MR, Nord M.

Am J Respir Crit Care Med. 2011 Jul 15;184(2):233-42. doi: 10.1164/rccm.201007-1113OC. Epub 2011 May 11.


Differential expression and function of breast regression protein 39 (BRP-39) in murine models of subacute cigarette smoke exposure and allergic airway inflammation.

Nikota JK, Botelho FM, Bauer CM, Jordana M, Coyle AJ, Humbles AA, Stampfli MR.

Respir Res. 2011 Apr 7;12:39. doi: 10.1186/1465-9921-12-39.


A mouse GM-CSF receptor antibody attenuates neutrophilia in mice exposed to cigarette smoke.

Botelho FM, Nikota JK, Bauer C, Davis NH, Cohen ES, Anderson IK, Coyle AJ, Kolbeck R, Humbles AA, Stämpfli MR, Sleeman MA.

Eur Respir J. 2011 Aug;38(2):285-94. doi: 10.1183/09031936.00076210. Epub 2011 Mar 24.


Cigarette smoke differentially affects eosinophilia and remodeling in a model of house dust mite asthma.

Botelho FM, Llop-Guevara A, Trimble NJ, Nikota JK, Bauer CM, Lambert KN, Kianpour S, Jordana M, Stämpfli MR.

Am J Respir Cell Mol Biol. 2011 Oct;45(4):753-60. doi: 10.1165/rcmb.2010-0404OC. Epub 2011 Feb 11.


Treating viral exacerbations of chronic obstructive pulmonary disease: insights from a mouse model of cigarette smoke and H1N1 influenza infection.

Bauer CM, Zavitz CC, Botelho FM, Lambert KN, Brown EG, Mossman KL, Taylor JD, Stämpfli MR.

PLoS One. 2010 Oct 12;5(10):e13251. doi: 10.1371/journal.pone.0013251.


Mechanisms of clearance of nontypeable Haemophilus influenzae from cigarette smoke-exposed mouse lungs.

Gaschler GJ, Zavitz CC, Bauer CM, Stämpfli MR.

Eur Respir J. 2010 Nov;36(5):1131-42. doi: 10.1183/09031936.00113909. Epub 2010 Apr 22.


Dysregulated macrophage-inflammatory protein-2 expression drives illness in bacterial superinfection of influenza.

Zavitz CC, Bauer CM, Gaschler GJ, Fraser KM, Strieter RM, Hogaboam CM, Stampfli MR.

J Immunol. 2010 Feb 15;184(4):2001-13. doi: 10.4049/jimmunol.0903304. Epub 2010 Jan 11.


Induction of the interleukin 6/ signal transducer and activator of transcription pathway in the lungs of mice sub-chronically exposed to mainstream tobacco smoke.

Halappanavar S, Russell M, Stampfli MR, Williams A, Yauk CL.

BMC Med Genomics. 2009 Aug 21;2:56. doi: 10.1186/1755-8794-2-56.


Exposure to cigarette smoke suppresses IL-15 generation and its regulatory NK cell functions in poly I:C-augmented human PBMCs.

Mian MF, Pek EA, Mossman KL, Stämpfli MR, Ashkar AA.

Mol Immunol. 2009 Sep;46(15):3108-16. doi: 10.1016/j.molimm.2009.06.009. Epub 2009 Jul 9.


Innate immune processes are sufficient for driving cigarette smoke-induced inflammation in mice.

Botelho FM, Gaschler GJ, Kianpour S, Zavitz CC, Trimble NJ, Nikota JK, Bauer CM, Stämpfli MR.

Am J Respir Cell Mol Biol. 2010 Apr;42(4):394-403. doi: 10.1165/rcmb.2008-0301OC. Epub 2009 Jun 5.


How cigarette smoke skews immune responses to promote infection, lung disease and cancer.

Stämpfli MR, Anderson GP.

Nat Rev Immunol. 2009 May;9(5):377-84. doi: 10.1038/nri2530. Review.


Acute, but not resolved, influenza A infection enhances susceptibility to house dust mite-induced allergic disease.

Al-Garawi AA, Fattouh R, Walker TD, Jamula EB, Botelho F, Goncharova S, Reed J, Stampfli MR, O'Byrne PM, Coyle AJ, Jordana M.

J Immunol. 2009 Mar 1;182(5):3095-104. doi: 10.4049/jimmunol.0802837.


Bacteria challenge in smoke-exposed mice exacerbates inflammation and skews the inflammatory profile.

Gaschler GJ, Skrtic M, Zavitz CC, Lindahl M, Onnervik PO, Murphy TF, Sethi S, Stämpfli MR.

Am J Respir Crit Care Med. 2009 Apr 15;179(8):666-75. doi: 10.1164/rccm.200808-1306OC. Epub 2009 Jan 29.


Cigarette smoke attenuation of poly I:C-induced innate antiviral responses in human PBMC is mainly due to inhibition of IFN-beta production.

Mian MF, Stämpfli MR, Mossman KL, Ashkar AA.

Mol Immunol. 2009 Feb;46(5):821-9. doi: 10.1016/j.molimm.2008.09.007. Epub 2008 Oct 18.


Toxicogenomic analysis of mainstream tobacco smoke-exposed mice reveals repression of plasminogen activator inhibitor-1 gene in heart.

Halappanavar S, Stampfli MR, Berndt-Weis L, Williams A, Douglas GR, Yauk CL.

Inhal Toxicol. 2009 Jan;21(1):78-85. doi: 10.1080/08958370802209165 .


Adjuvant and anti-inflammatory properties of cigarette smoke in murine allergic airway inflammation.

Trimble NJ, Botelho FM, Bauer CM, Fattouh R, Stämpfli MR.

Am J Respir Cell Mol Biol. 2009 Jan;40(1):38-46. doi: 10.1165/rcmb.2008-0107OC. Epub 2008 Jul 17.


Impact of cigarette smoke on T and B cell responsiveness.

Zavitz CC, Gaschler GJ, Robbins CS, Botelho FM, Cox PG, Stampfli MR.

Cell Immunol. 2008 May-Jun;253(1-2):38-44. doi: 10.1016/j.cellimm.2008.04.012. Epub 2008 Jun 3.


Cigarette smoke suppresses type I interferon-mediated antiviral immunity in lung fibroblast and epithelial cells.

Bauer CM, Dewitte-Orr SJ, Hornby KR, Zavitz CC, Lichty BD, Stämpfli MR, Mossman KL.

J Interferon Cytokine Res. 2008 Mar;28(3):167-79. doi: 10.1089/jir.2007.0054.


Impairment of human NK cell cytotoxic activity and cytokine release by cigarette smoke.

Mian MF, Lauzon NM, Stämpfli MR, Mossman KL, Ashkar AA.

J Leukoc Biol. 2008 Mar;83(3):774-84. Epub 2007 Nov 30.


Cigarette smoke exposure attenuates cytokine production by mouse alveolar macrophages.

Gaschler GJ, Zavitz CC, Bauer CM, Skrtic M, Lindahl M, Robbins CS, Chen B, Stämpfli MR.

Am J Respir Cell Mol Biol. 2008 Feb;38(2):218-26. Epub 2007 Sep 13.


Animal models of chronic obstructive pulmonary disease exacerbations.

Gaschler GJ, Bauer CM, Zavitz CC, Stämpfli MR.

Contrib Microbiol. 2007;14:126-41. Review.


Divergent immune responses to house dust mite lead to distinct structural-functional phenotypes.

Johnson JR, Swirski FK, Gajewska BU, Wiley RE, Fattouh R, Pacitto SR, Wong JK, Stämpfli MR, Jordana M.

Am J Physiol Lung Cell Mol Physiol. 2007 Sep;293(3):L730-9. Epub 2007 Jun 22.


Mainstream tobacco smoke causes paternal germ-line DNA mutation.

Yauk CL, Berndt ML, Williams A, Rowan-Carroll A, Douglas GR, Stämpfli MR.

Cancer Res. 2007 Jun 1;67(11):5103-6.


Kinetics of in vitro bronchoconstriction in an elastolytic mouse model of emphysema.

Khan MA, Kianpour S, Stämpfli MR, Janssen LJ.

Eur Respir J. 2007 Oct;30(4):691-700. Epub 2007 May 30.


Cigarette smoke impairs NK cell-dependent tumor immune surveillance.

Lu LM, Zavitz CC, Chen B, Kianpour S, Wan Y, Stämpfli MR.

J Immunol. 2007 Jan 15;178(2):936-43.


Cigarette smoke impacts immune inflammatory responses to influenza in mice.

Robbins CS, Bauer CM, Vujicic N, Gaschler GJ, Lichty BD, Brown EG, Stämpfli MR.

Am J Respir Crit Care Med. 2006 Dec 15;174(12):1342-51. Epub 2006 Oct 5.


Prolonged ovalbumin exposure attenuates airway hyperresponsiveness and T cell function in mice.

Swirski FK, D'Sa A, Kianpour S, Inman MD, Stämpfli MR.

Int Arch Allergy Immunol. 2006;141(2):130-40. Epub 2006 Jul 21.


Inhalation tolerance is induced selectively in thoracic lymph nodes but executed pervasively at distant mucosal and nonmucosal tissues.

Alvarez D, Swirski FK, Yang TC, Fattouh R, Croitoru K, Bramson JL, Stämpfli MR, Jordana M.

J Immunol. 2006 Feb 15;176(4):2568-80.


Mainstream cigarette smoke exposure attenuates airway immune inflammatory responses to surrogate and common environmental allergens in mice, despite evidence of increased systemic sensitization.

Robbins CS, Pouladi MA, Fattouh R, Dawe DE, Vujicic N, Richards CD, Jordana M, Inman MD, Stampfli MR.

J Immunol. 2005 Sep 1;175(5):2834-42.


B7RP-1 is not required for the generation of Th2 responses in a model of allergic airway inflammation but is essential for the induction of inhalation tolerance.

Gajewska BU, Tafuri A, Swirski FK, Walker T, Johnson JR, Shea T, Shahinian A, Goncharova S, Mak TW, Stämpfli MR, Jordana M.

J Immunol. 2005 Mar 1;174(5):3000-5.


Cutaneous antigen priming via gene gun leads to skin-selective Th2 immune-inflammatory responses.

Alvarez D, Harder G, Fattouh R, Sun J, Goncharova S, Stämpfli MR, Coyle AJ, Bramson JL, Jordana M.

J Immunol. 2005 Feb 1;174(3):1664-74.


The lung cytokine microenvironment influences molecular events in the lymph nodes during Th1 and Th2 respiratory mucosal sensitization to antigen in vivo.

Ritz SA, Cundall MJ, Gajewska BU, Swirski FK, Wiley RE, Alvarez D, Coyle AJ, Stampfli MR, Jordana M.

Clin Exp Immunol. 2004 Nov;138(2):213-20.


Impact of cigarette smoke on clearance and inflammation after Pseudomonas aeruginosa infection.

Drannik AG, Pouladi MA, Robbins CS, Goncharova SI, Kianpour S, Stämpfli MR.

Am J Respir Crit Care Med. 2004 Dec 1;170(11):1164-71. Epub 2004 Aug 18.


Concomitant airway expression of granulocyte-macrophage colony-stimulating factor and decorin, a natural inhibitor of transforming growth factor-beta, breaks established inhalation tolerance.

Swirski FK, Gajewska BU, Robbins CS, D'Sa A, Johnson JR, Pouladi MA, Inman MD, Stämpfli MR.

Eur J Immunol. 2004 Sep;34(9):2375-86.


Cigarette smoke decreases pulmonary dendritic cells and impacts antiviral immune responsiveness.

Robbins CS, Dawe DE, Goncharova SI, Pouladi MA, Drannik AG, Swirski FK, Cox G, Stämpfli MR.

Am J Respir Cell Mol Biol. 2004 Feb;30(2):202-11. Epub 2003 Aug 14.


Interleukin-13-dependent expression of matrix metalloproteinase-12 is required for the development of airway eosinophilia in mice.

Pouladi MA, Robbins CS, Swirski FK, Cundall M, McKenzie AN, Jordana M, Shapiro SD, Stämpfli MR.

Am J Respir Cell Mol Biol. 2004 Jan;30(1):84-90. Epub 2003 Jul 3.


Granulocyte macrophage colony-stimulating factor-driven respiratory mucosal sensitization induces Th2 differentiation and function independently of interleukin-4.

Ritz SA, Cundall MJ, Gajewska BU, Alvarez D, Gutierrez-Ramos JC, Coyle AJ, McKenzie AN, Stämpfli MR, Jordana M.

Am J Respir Cell Mol Biol. 2002 Oct;27(4):428-35.


On the generation of allergic airway diseases: from GM-CSF to Kyoto.

Ritz SA, Stämpfli MR, Davies DE, Holgate ST, Jordana M.

Trends Immunol. 2002 Aug;23(8):396-402. Review.


Inhalation of a harmless antigen (ovalbumin) elicits immune activation but divergent immunoglobulin and cytokine activities in mice.

Swirski FK, Gajewska BU, Alvarez D, Ritz SA, Cundall MJ, Cates EC, Coyle AJ, Gutierrez-Ramos JC, Inman MD, Jordana M, Stämpfli MR.

Clin Exp Allergy. 2002 Mar;32(3):411-21.


Temporal-spatial analysis of the immune response in a murine model of ovalbumin-induced airways inflammation.

Gajewska BU, Swirski FK, Alvarez D, Ritz SA, Goncharova S, Cundall M, Snider DP, Coyle AJ, Gutierrez-Ramos JC, Stämpfli MR, Jordana M.

Am J Respir Cell Mol Biol. 2001 Sep;25(3):326-34.


Generation of experimental allergic airways inflammation in the absence of draining lymph nodes.

Gajewska BU, Alvarez D, Vidric M, Goncharova S, Stämpfli MR, Coyle AJ, Gutierrez-Ramos JC, Jordana M.

J Clin Invest. 2001 Aug;108(4):577-83.


Determinants of the immune-inflammatory response in allergic airway inflammation: overview of antigen presentation and cellular activation.

Ritz SA, Gajewska BU, Stämpfli MR, Jordana M.

J Allergy Clin Immunol. 2000 Nov;106(5 Suppl):S206-12. Review.


Interaction of human IgE with Fc epsilon RI alpha exposes hidden epitopes on IgE.

Nechansky A, Ruf C, Pursch E, Wasserbauer E, Stämpfli MR, Pachlopnik JM, Stadler BM, Kricek F.

Int Arch Allergy Immunol. 1999 Dec;120(4):295-302.


Transient Transgenic Approaches for Investigating the Role of GM-CSF in Pulmonary Inflammation and Immune Diseases.

Xing Z, Stämpfli MR, Gauldie J.

Methods Mol Med. 2000;44:161-78. doi: 10.1385/1-59259-072-1:161.


Interleukin-10 gene transfer to the airway regulates allergic mucosal sensitization in mice.

Stämpfli MR, Cwiartka M, Gajewska BU, Alvarez D, Ritz SA, Inman MD, Xing Z, Jordana M.

Am J Respir Cell Mol Biol. 1999 Nov;21(5):586-96.


Regulation of allergic mucosal sensitization by interleukin-12 gene transfer to the airway.

Stämpfli MR, Scott Neigh G, Wiley RE, Cwiartka M, Ritz SA, Hitt MM, Xing Z, Jordana M.

Am J Respir Cell Mol Biol. 1999 Sep;21(3):317-26.


Adenoviral infection inhibits allergic airways inflammation in mice.

Stämpfli MR, Ritz SA, Neigh GS, Sime PJ, Lei XF, Xing Z, Croitoru K, Jordana M.

Clin Exp Allergy. 1998 Dec;28(12):1581-90.


Antigen interaction and heat inactivation expose new epitopes on human IgE.

Pachlopnik JM, Stämpfli MR, Rudolf MP, Aebischer I, Kricek F, Miescher S, Stadler BM.

Int Arch Allergy Immunol. 1998 Dec;117(4):231-8.


GM-CSF transgene expression in the airway allows aerosolized ovalbumin to induce allergic sensitization in mice.

Stämpfli MR, Wiley RE, Neigh GS, Gajewska BU, Lei XF, Snider DP, Xing Z, Jordana M.

J Clin Invest. 1998 Nov 1;102(9):1704-14.


Eosinophilia in antigen-induced airways inflammation.

Stämpfli MR, Jordana M.

Can Respir J. 1998 Jul-Aug;5 Suppl A:31A-5A. Review.


Compartmentalized transgene expression of granulocyte-macrophage colony-stimulating factor (GM-CSF) in mouse lung enhances allergic airways inflammation.

Lei XF, Ohkawara Y, Stämpfli MR, Gauldie J, Croitoru K, Jordana M, Xing Z.

Clin Exp Immunol. 1998 Aug;113(2):157-65.


Disruption of antigen-induced inflammatory responses in CD40 ligand knockout mice.

Lei XF, Ohkawara Y, Stämpfli MR, Mastruzzo C, Marr RA, Snider D, Xing Z, Jordana M.

J Clin Invest. 1998 Mar 15;101(6):1342-53.


Cytokine and eosinophil responses in the lung, peripheral blood, and bone marrow compartments in a murine model of allergen-induced airways inflammation.

Ohkawara Y, Lei XF, Stämpfli MR, Marshall JS, Xing Z, Jordana M.

Am J Respir Cell Mol Biol. 1997 May;16(5):510-20.


Neuropeptides accentuate interleukin-4 induced human immunoglobuline E synthesis in vitro.

Aebischer I, Stämpfli MR, Miescher S, Horn M, Zürcher AW, Stadler BM.

Exp Dermatol. 1996 Feb;5(1):38-44.


Antigen-specific inhibition of IgE binding to the high-affinity receptor.

Stämpfli MR, Rudolf M, Miescher S, Pachlopnik JM, Stadler BM.

J Immunol. 1995 Sep 15;155(6):2948-54.


Cloning of human anti-IgE autoantibodies and their role in the regulation of IgE synthesis.

Stadler BM, Stämpfli MR, Miescher S, Rudolf M, Vogel M.

Int Arch Allergy Immunol. 1995 May-Jun;107(1-3):48-50. Review.


Domain-specific anti-IgE antibodies interfere with IgE binding to Fc epsilon RII.

Miescher S, Vogel M, Stämpfli MR, Wasserbauer E, Kricek F, Vorburger S, Stadler BM.

Int Arch Allergy Immunol. 1994 Sep;105(1):75-82.


Inhibition of human IgE synthesis by anti-IgE antibodies requires divalent recognition.

Stämpfli MR, Miescher S, Aebischer I, Zürcher AW, Stadler BM.

Eur J Immunol. 1994 Sep;24(9):2161-7.


Neuropeptides are potent modulators of human in vitro immunoglobulin E synthesis.

Aebischer I, Stämpfli MR, Zürcher A, Miescher S, Urwyler A, Frey B, Luger T, White RR, Stadler BM.

Eur J Immunol. 1994 Aug;24(8):1908-13.


Neuroendocrine and autoimmune regulation of the allergic response.

Stadler BM, Aebischer I, Stämpfli MR, Miescher S, Vogel M.

Arb Paul Ehrlich Inst Bundesamt Sera Impfstoffe Frankf A M. 1994;(87):293-9. No abstract available.


A specific feedback by anti-IgE autoantibodies on the cytokine network in allergy.

Stadler BM, Stämpfli MR, Vogel M, Aebischer I, Furukawa K, Holzner ME, Rudolf MP, Miescher S.

Agents Actions Suppl. 1993;40:144-52. Review.


Biological activities of anti-IgE antibodies.

Stadler BM, Stämpfli MR, Miescher S, Furukawa K, Vogel M.

Int Arch Allergy Immunol. 1993;102(2):121-6. Review.


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