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Items: 1 to 20 of 11005


Neonicotinoid insecticides mode of action on insect nicotinic acetylcholine receptors using binding studies.

Taillebois E, Cartereau A, Jones AK, Thany SH.

Pestic Biochem Physiol. 2018 Oct;151:59-66. doi: 10.1016/j.pestbp.2018.04.007. Epub 2018 Apr 19. Review.


Combined effects of mutations in loop C and the loop D-E-G triangle on neonicotinoid interactions with Drosophila Dα1/chicken β2 hybrid nAChRs.

Hikida M, Shimada S, Kurata R, Shigetou S, Ihara M, Sattelle DB, Matsuda K.

Pestic Biochem Physiol. 2018 Oct;151:47-52. doi: 10.1016/j.pestbp.2018.03.008. Epub 2018 Mar 27.


Menthol Stereoisomers Exhibit Different Effects on α4β2 nAChR Upregulation and Dopamine Neuron Spontaneous Firing.

Henderson BJ, Grant S, Chu BW, Shahoei R, Huard SM, Saladi SSM, Tajkhorshid E, Dougherty DA, Lester HA.

eNeuro. 2019 Jan 4;5(6). pii: ENEURO.0465-18.2018. doi: 10.1523/ENEURO.0465-18.2018. eCollection 2018 Nov-Dec.


Polyarginine Peptides As a New Class of Ligands of Nicotinic Acetylcholine Receptors.

Kryukova EV, Ivanov IA, Lebedev DS, Spirova EN, Senko DA, Egorova NS, Kasheverov IE, Tsetlin VI.

Dokl Biochem Biophys. 2018 Nov;483(1):313-315. doi: 10.1134/S1607672918060017. Epub 2019 Jan 3.


Alpha 7 nicotinic acetylcholine receptor and its effects on Alzheimer's disease.

Ma KG, Qian YH.

Neuropeptides. 2019 Feb;73:96-106. doi: 10.1016/j.npep.2018.12.003. Epub 2018 Dec 18. Review.


Alanine-Scanning Mutagenesis of α-Conotoxin GI Reveals the Residues Crucial for Activity at the Muscle Acetylcholine Receptor.

Ning J, Li R, Ren J, Zhangsun D, Zhu X, Wu Y, Luo S.

Mar Drugs. 2018 Dec 13;16(12). pii: E507. doi: 10.3390/md16120507.


TRPC channels mediated calcium entry is required for proliferation of human airway smooth muscle cells induced by nicotine-nAChR.

Jiang Y, Zhou Y, Peng G, Tian H, Pan D, Liu L, Yang X, Li C, Li W, Chen L, Ran P, Dai A.

Biochimie. 2019 Mar;158:139-148. doi: 10.1016/j.biochi.2018.12.004. Epub 2018 Dec 11.


Designing Hybrids Targeting the Cholinergic System by Modulating the Muscarinic and Nicotinic Receptors: A Concept to Treat Alzheimer's Disease.

Volpato D, Holzgrabe U.

Molecules. 2018 Dec 7;23(12). pii: E3230. doi: 10.3390/molecules23123230. Review.


Nicotine-sensitive acetylcholine receptors are relevant pharmacological targets for the control of multidrug resistant parasitic nematodes.

Charvet CL, Guégnard F, Courtot E, Cortet J, Neveu C.

Int J Parasitol Drugs Drug Resist. 2018 Dec;8(3):540-549. doi: 10.1016/j.ijpddr.2018.11.003. Epub 2018 Nov 20.


Orthosteric and/or Allosteric Binding of α-Conotoxins to Nicotinic Acetylcholine Receptors and Their Models.

Kryukova EV, Ivanov IA, Lebedev DS, Spirova EN, Egorova NS, Zouridakis M, Kasheverov IE, Tzartos SJ, Tsetlin VI.

Mar Drugs. 2018 Nov 22;16(12). pii: E460. doi: 10.3390/md16120460.


Combined genetic influence of the nicotinic receptor gene cluster CHRNA5/A3/B4 on nicotine dependence.

Lee SH, Ahn WY, Seweryn M, Sadee W.

BMC Genomics. 2018 Nov 20;19(1):826. doi: 10.1186/s12864-018-5219-3.


Time-dependent effect of oligomeric amyloid-β (1-42)-induced hippocampal neurodegeneration in rat model of Alzheimer's disease.

Karthick C, Nithiyanandan S, Essa MM, Guillemin GJ, Jayachandran SK, Anusuyadevi M.

Neurol Res. 2019 Feb;41(2):139-150. doi: 10.1080/01616412.2018.1544745. Epub 2018 Nov 19.


[β2-nicotinic acetylcholine receptor promotes development of GABAA receptors in mouse hippocampal CA1 and CA3 pyramidal neurons].

Zheng C, Huang Y, Zhang H, Zha Y, Wang M.

Nan Fang Yi Ke Da Xue Xue Bao. 2018 Aug 30;38(9):1045-1051. doi: 10.12122/j.issn.1673-4254.2018.09.04. Chinese.


[Low-intensity pulsed ultrasound pretreatment inhibits HMGB1 expression and attenuates lung ischemia-reperfusion injury in rats via the cholinergic anti-inflammatory pathway].

Qu L, Yan J, Jiang Z, Song Z, Luo F, Peng Q.

Nan Fang Yi Ke Da Xue Xue Bao. 2018 Aug 30;38(9):1061-1065. doi: 10.12122/j.issn.1673-4254.2018.09.06. Chinese.


Protective effect of α-asarone against nicotine-induced seizures in mice, but not by its interaction with nicotinic acetylcholine receptors.

Chellian R, Pandy V.

Biomed Pharmacother. 2018 Dec;108:1591-1595. doi: 10.1016/j.biopha.2018.09.137. Epub 2018 Oct 9.


Amphetamine enantiomers inhibit homomeric α7 nicotinic receptor through a competitive mechanism and within the intoxication levels in humans.

Garton DR, Ross SG, Maldonado-Hernández R, Quick M, Lasalde-Dominicci JA, Lizardi-Ortiz JE.

Neuropharmacology. 2019 Jan;144:172-183. doi: 10.1016/j.neuropharm.2018.10.032. Epub 2018 Oct 23.


Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes.

Clemmensen C, Jall S, Kleinert M, Quarta C, Gruber T, Reber J, Sachs S, Fischer K, Feuchtinger A, Karlas A, Simonds SE, Grandl G, Loher D, Sanchez-Quant E, Keipert S, Jastroch M, Hofmann SM, Nascimento EBM, Schrauwen P, Ntziachristos V, Cowley MA, Finan B, Müller TD, Tschöp MH.

Nat Commun. 2018 Oct 23;9(1):4304. doi: 10.1038/s41467-018-06769-y. Erratum in: Nat Commun. 2018 Nov 20;9(1):4975.


Novel 5-(quinuclidin-3-ylmethyl)-1,2,4-oxadiazoles to investigate the activation of the α7 nicotinic acetylcholine receptor subtype: Synthesis and electrophysiological evaluation.

Quadri M, Silnović A, Matera C, Horenstein NA, Stokes C, De Amici M, Papke RL, Dallanoce C.

Eur J Med Chem. 2018 Dec 5;160:207-228. doi: 10.1016/j.ejmech.2018.10.015. Epub 2018 Oct 11.


Discovery, cocrystallization and biological evaluation of novel piperidine derivatives as high affinity Ls-AChBP ligands possessing α7 nAChR activities.

Yang X, Shen J, Jiang L, Li W, Yu M, Pan G, Yan Y, Zhang C, Jia W, Xiao L, Yu H, Chen H, Zheng Y, Yu L, Xie Q, Zhou L, Shao L.

Eur J Med Chem. 2018 Dec 5;160:37-48. doi: 10.1016/j.ejmech.2018.09.073. Epub 2018 Oct 3.


CHRFAM7A alters binding to the neuronal alpha-7 nicotinic acetylcholine receptor.

Chan T, Williams E, Cohen O, Eliceiri BP, Baird A, Costantini TW.

Neurosci Lett. 2019 Jan 18;690:126-131. doi: 10.1016/j.neulet.2018.10.010. Epub 2018 Oct 9.


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