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North Clin Istanb. 2019 Nov 22;6(4):412-414. doi: 10.14744/nci.2018.90922. eCollection 2019.

Coexistence of ankylosing spondylitis and discoid lupus: A case report.

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Department of Physical Medicine and Rehabilitation, Akdeniz University Faculty of Medicine, Antalya, Turkey.


Coexistence of ankylosing spondylitis with connective tissue diseases is very rare. Here, in this study, we describe a coexistence of ankylosing spondylitis and discoid lupus erythematosus in a 35-year-old man. He presented with a 5-year history of low back pain and concurrent development of a discoid rash. Inflammatory low back pain, HLA-B27 positivity and bilateral active sacroiliitis confirmed the diagnosis of ankylosing spondylitis. Discoid lupus erythematosus was diagnosed based on a skin biopsy. There are reports of discoid lupus associated with medications, particularly with tumour necrosis factor-alpha (TNF-α) blocking drugs. However, the patient presented here had coexistence of ankylosing spondylitis and discoid lupus before starting such treatments.


Ankylosing spondylitis; discoid lupus; systemic lupus erythematosus

Conflict of interest statement

Conflict of Interest: No conflict of interest was declared by the authors.

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