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Ulus Travma Acil Cerrahi Derg. 2019 Aug;25(5):520-526. doi: 10.14744/tjtes.2019.24358.

Our experience with dermal substitute Nevelia® in the treatment of severely burned patients.

Author information

1
Department of General Surgery, Health Sciences University Bağcılar Training and Research Hospital, İstanbul-Turkey.
2
Department of Biochemistry, Health Sciences University Faculty of Medicine, İstanbul-Turkey.
3
Department of General Surgery, Health Sciences University Ankara Numune Training and Research Hospital, Ankara-Turkey.
4
Department of Histology and Embryology, Health Sciences University Faculty of Medicine, İstanbul-Turkey.

Abstract

BACKGROUND:

This research aims to retrospectively evaluate the effectiveness and safety of dermal substitute (DS), Nevelia®, for the treatment of severely burned patients.

METHODS:

Twenty severely burned patients were enrolled in this study between May 2017 and May 2018. After escharotomy of the wound, the treatment protocol was applied following a two-step procedure -DS implantation followed by split-thickness skin graft (STSG) application. Need for surgery, complications, hospitalisation duration and overall survival were analysed.

RESULTS:

Mean age was 40.1±4 (18-86) years old; female/male: 5/15. Mean burn surface area was 50.1%±2 (25-96). Two patients died under hospital treatment due to the severity of their burn trauma and comorbidities. For the rest of the cases, STSG was performed after Nevelia® at mean 21.2 days. No complications due to Nevelia® were detected. The patients were discharged with a mean total recovery of 55.2±4 days.

CONCLUSION:

This study showed that Nevelia® can be used safely and effectively in severely burned patients with low complication rates and short hospital stay.

PMID:
31475321
DOI:
10.14744/tjtes.2019.24358
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