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Ulus Travma Acil Cerrahi Derg. 2019 Jul;25(4):338-342. doi: 10.14744/tjtes.2019.38265.

Comparison of Ankaferd Blood Stopper and silver sulfadiazine use in burn wounds: An experimental study.

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Department of General Surgery, KTO Karatay University Faculty of Medicine, Konya-Turkey.
Department of Pathology, Health Sciences University Konya Training and Research Hospital, Konya-Turkey.



The present study was designed to compare the effectiveness of topical silver sulfadiazine (SSD) and Ankaferd Blood Stopper® (ABS) usage in experimental partial-thickness burns in rats.


Twenty-one male Wistar albino rats weighing 250-290 (range: 270+-19) g were used in the present study. A round brass probe that was specifically designed (3×3 cm diameter) was used to induce the burns in rats. After the presence of partial-thickness burns was confirmed, the rats were divided into three groups: Group 1 (ABS group) Ankaferd Blood Stopper® pad, Group 2 (SSD group) silver sulfadiazine (Silverdin®), and Group 3 (Control group) 1% isotonic saline solution-impregnated pad. The healing period was followed up clinically and histopathologically. The day on which 50% and 80% of re-epithelization at first were detected for each rat was also recorded.


The mean times of 50% and 80% of re-epithelization at first were 10.8 days, 13.8 days, and 16.8 days in Groups 1, 2, and 3, respectively (p<0.001), and 16.4 days, 19.7 days, and 25.2 days, respectively (p<0.001). The mean inflammatory scores were also found to be better in the ABS group than in other groups (p<0.05).


Our study showed that ABS has better results for the healing of the burn wound than SSD in experimental partial-thickness burns in rats.

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