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Turk Kardiyol Dern Ars. 2019 Jan;47(1):63-68. doi: 10.5543/tkda.2018.83364.

Is the use of low molecular weight heparin a rational choice during pregnancy in patients with a mechanical heart valve: a report of three cases.

Author information

1
Department of Cardiology, Kartal Koşuyolu High Speciality Training and Research Hospital, İstanbul, Turkey. ahmetguner488@gmail.com.

Abstract

Pregnancy is associated with an increased risk of valve thrombosis in patients with a mechanical prosthetic heart valve. The administration of low molecular weight heparin (LMWH) with regular anti-factor Xa assessment is a recommended treatment modality for these patients. Presently described are 3 cases of therapy with LMWH during pregnancy. Despite frequent anti-factor Xa monitoring, not surprisingly, all of them developed prosthetic valve thrombosis.

PMID:
30628904
DOI:
10.5543/tkda.2018.83364
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