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Agri. 2017 Oct;29(4):173-176. doi: 10.5505/agri.2017.91328.

Methemoglobinemia incidence after the application of lidocaine for small surgical procedures.

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Department of Nursing, Kafkas University Faculty of Health Sciences, Kars, Turkey.



Methemoglobinemia (MetHb) is a rare condition that may have mortal consequences. Literature shows cases of methemoglobinemia due to the use of lidocaine and other local anesthetics. This is a cross-sectional study to determine the incidence of methemoglobinemia after the application of lidocaine.


In this study, 88 patients admitted to the emergency department of a university hospital between May 2014 and May 2015 and needed lidocaine application for small surgical procedures were included. When compared before and after the administration of lidocaine <2 mg/kg and >2 mg/kg, there was not a significant difference in the level of methemoglobin, hemoglobin, or in the hematocrit (p=0.604, p=0.502, and p=0.367, respectively).


Mean age of the patients was 33.85 (±17.58) years, and 83% of the patients were male. Methemoglobin levels were not significantly different before and after the procedures (p>0.05).


The results of our study were consistent with the literature; lidocaine associated methemoglobinemia is a rare complication.

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