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Items: 1 to 20 of 102

1.

Inflammation-induced DNA methylation of DNA polymerase gamma alters the metabolic profile of colon tumors.

Maiuri AR, Li H, Stein BD, Tennessen JM, O'Hagan HM.

Cancer Metab. 2018 Jul 10;6:9. doi: 10.1186/s40170-018-0182-7. eCollection 2018.

2.

A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers.

Xu S, Catapang A, Braas D, Stiles L, Doh HM, Lee JT, Graeber TG, Damoiseaux R, Shirihai O, Herschman HR.

Cancer Metab. 2018 Jun 28;6:7. doi: 10.1186/s40170-018-0181-8. eCollection 2018.

3.

Beta-hydroxybutyrate (3-OHB) can influence the energetic phenotype of breast cancer cells, but does not impact their proliferation and the response to chemotherapy or radiation.

Bartmann C, Janaki Raman SR, Flöter J, Schulze A, Bahlke K, Willingstorfer J, Strunz M, Wöckel A, Klement RJ, Kapp M, Djuzenova CS, Otto C, Kämmerer U.

Cancer Metab. 2018 Jun 11;6:8. doi: 10.1186/s40170-018-0180-9. eCollection 2018.

4.

Isoform-specific deletion of PKM2 constrains tumor initiation in a mouse model of soft tissue sarcoma.

Dayton TL, Gocheva V, Miller KM, Bhutkar A, Lewis CA, Bronson RT, Vander Heiden MG, Jacks T.

Cancer Metab. 2018 May 31;6:6. doi: 10.1186/s40170-018-0179-2. eCollection 2018.

5.

Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities.

Garrett M, Sperry J, Braas D, Yan W, Le TM, Mottahedeh J, Ludwig K, Eskin A, Qin Y, Levy R, Breunig JJ, Pajonk F, Graeber TG, Radu CG, Christofk H, Prins RM, Lai A, Liau LM, Coppola G, Kornblum HI.

Cancer Metab. 2018 Apr 17;6:4. doi: 10.1186/s40170-018-0177-4. eCollection 2018.

6.

Metabolomics of oncogene-specific metabolic reprogramming during breast cancer.

Dai C, Arceo J, Arnold J, Sreekumar A, Dovichi NJ, Li J, Littlepage LE.

Cancer Metab. 2018 Apr 3;6:5. doi: 10.1186/s40170-018-0175-6. eCollection 2018.

7.

Mutant IDH1 gliomas downregulate phosphocholine and phosphoethanolamine synthesis in a 2-hydroxyglutarate-dependent manner.

Viswanath P, Radoul M, Izquierdo-Garcia JL, Luchman HA, Gregory Cairncross J, Pieper RO, Phillips JJ, Ronen SM.

Cancer Metab. 2018 Apr 3;6:3. doi: 10.1186/s40170-018-0178-3. eCollection 2018.

8.

Elevated circulatory levels of leptin and resistin impair therapeutic efficacy of dacarbazine in melanoma under obese state.

Malvi P, Chaube B, Singh SV, Mohammad N, Vijayakumar MV, Singh S, Chouhan S, Bhat MK.

Cancer Metab. 2018 Mar 20;6:2. doi: 10.1186/s40170-018-0176-5. eCollection 2018.

9.

Cancer cell metabolic plasticity allows resistance to NAMPT inhibition but invariably induces dependence on LDHA.

Thongon N, Zucal C, D'Agostino VG, Tebaldi T, Ravera S, Zamporlini F, Piacente F, Moschoi R, Raffaelli N, Quattrone A, Nencioni A, Peyron JF, Provenzani A.

Cancer Metab. 2018 Mar 8;6:1. doi: 10.1186/s40170-018-0174-7. eCollection 2018.

10.

Human mitochondrial MTHFD2 is a dual redox cofactor-specific methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase.

Shin M, Momb J, Appling DR.

Cancer Metab. 2017 Dec 6;5:11. doi: 10.1186/s40170-017-0173-0. eCollection 2017.

11.

PKM2 is not required for colon cancer initiated by APC loss.

Lau AN, Israelsen WJ, Roper J, Sinnamon MJ, Georgeon L, Dayton TL, Hillis AL, Yilmaz OH, Di Vizio D, Hung KE, Vander Heiden MG.

Cancer Metab. 2017 Nov 30;5:10. doi: 10.1186/s40170-017-0172-1. eCollection 2017.

12.

Metabolomics guided pathway analysis reveals link between cancer metastasis, cholesterol sulfate, and phospholipids.

Johnson CH, Santidrian AF, LeBoeuf SE, Kurczy ME, Rattray NJW, Rattray Z, Warth B, Ritland M, Hoang LT, Loriot C, Higa J, Hansen JE, Felding BH, Siuzdak G.

Cancer Metab. 2017 Oct 31;5:9. doi: 10.1186/s40170-017-0171-2. eCollection 2017.

13.

Molecular features that predict the response to antimetabolite chemotherapies.

Mehrmohamadi M, Jeong SH, Locasale JW.

Cancer Metab. 2017 Oct 3;5:8. doi: 10.1186/s40170-017-0170-3. eCollection 2017.

14.

Bortezomib resistance in multiple myeloma is associated with increased serine synthesis.

Zaal EA, Wu W, Jansen G, Zweegman S, Cloos J, Berkers CR.

Cancer Metab. 2017 Aug 29;5:7. doi: 10.1186/s40170-017-0169-9. eCollection 2017.

15.

Metabolic profiling of triple-negative breast cancer cells reveals metabolic vulnerabilities.

Lanning NJ, Castle JP, Singh SJ, Leon AN, Tovar EA, Sanghera A, MacKeigan JP, Filipp FV, Graveel CR.

Cancer Metab. 2017 Aug 22;5:6. doi: 10.1186/s40170-017-0168-x. eCollection 2017.

16.

HIF prolyl hydroxylase PHD3 regulates translational machinery and glucose metabolism in clear cell renal cell carcinoma.

Miikkulainen P, Högel H, Rantanen K, Suomi T, Kouvonen P, Elo LL, Jaakkola PM.

Cancer Metab. 2017 Jul 4;5:5. doi: 10.1186/s40170-017-0167-y. eCollection 2017.

17.

The action of β-hydroxybutyrate on the growth, metabolism and global histone H3 acetylation of spontaneous mouse mammary tumours: evidence of a β-hydroxybutyrate paradox.

Rodrigues LM, Uribe-Lewis S, Madhu B, Honess DJ, Stubbs M, Griffiths JR.

Cancer Metab. 2017 Feb 28;5:4. doi: 10.1186/s40170-017-0166-z. eCollection 2017.

18.

The α-ketoglutarate dehydrogenase complex in cancer metabolic plasticity.

Vatrinet R, Leone G, De Luise M, Girolimetti G, Vidone M, Gasparre G, Porcelli AM.

Cancer Metab. 2017 Feb 2;5:3. doi: 10.1186/s40170-017-0165-0. eCollection 2017. Review.

19.

Mitochondrial mutations and metabolic adaptation in pancreatic cancer.

Hardie RA, van Dam E, Cowley M, Han TL, Balaban S, Pajic M, Pinese M, Iconomou M, Shearer RF, McKenna J, Miller D, Waddell N, Pearson JV, Grimmond SM; Australian Pancreatic Cancer Genome Initiative, Sazanov L, Biankin AV, Villas-Boas S, Hoy AJ, Turner N, Saunders DN.

Cancer Metab. 2017 Jan 30;5:2. doi: 10.1186/s40170-017-0164-1. eCollection 2017.

20.

Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration.

Balaban S, Shearer RF, Lee LS, van Geldermalsen M, Schreuder M, Shtein HC, Cairns R, Thomas KC, Fazakerley DJ, Grewal T, Holst J, Saunders DN, Hoy AJ.

Cancer Metab. 2017 Jan 13;5:1. doi: 10.1186/s40170-016-0163-7. eCollection 2017.

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