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Items: 1 to 20 of 1236


Independent effects of dietary fat and sucrose content on chondrocyte metabolism and osteoarthritis pathology in mice.

Donovan EL, Lopes EBP, Batushansky A, Kinter M, Griffin TM.

Dis Model Mech. 2018 Jul 16. pii: dmm.034827. doi: 10.1242/dmm.034827. [Epub ahead of print]


A Langendorff-like system to quantify cardiac pump function in adult zebrafish.

Zhang H, Dvornikov AV, Huttner IG, Ma X, Santiago CF, Fatkin D, Xu X.

Dis Model Mech. 2018 Jul 16. pii: dmm.034819. doi: 10.1242/dmm.034819. [Epub ahead of print]


Intravital microscopy of collective invasion plasticity in breast cancer.

Ilina O, Campanello L, Gritsenko PG, Vullings M, Wang C, Bult P, Losert W, Friedl P.

Dis Model Mech. 2018 Jul 11. pii: dmm.034330. doi: 10.1242/dmm.034330. [Epub ahead of print]


Metabolic traits of cancer stem cells.

Peixoto J, Lima J.

Dis Model Mech. 2018 Jun 28;11(8). pii: dmm033464. doi: 10.1242/dmm.033464. Review.


The metabolic axis of macrophage and immune cell polarization.

Hobson-Gutierrez SA, Carmona-Fontaine C.

Dis Model Mech. 2018 Jul 6;11(8). pii: dmm034462. doi: 10.1242/dmm.034462. Review.


Hidden features: exploring the non-canonical functions of metabolic enzymes.

Huangyang P, Simon MC.

Dis Model Mech. 2018 Jul 6;11(8). pii: dmm033365. doi: 10.1242/dmm.033365. Review.


Fetal articular cartilage regeneration versus adult fibrocartilaginous repair: secretome proteomics unravels molecular mechanisms in an ovine model.

Ribitsch I, Mayer RL, Egerbacher M, Gabner S, Kańduła MM, Rosser J, Haltmayer E, Auer U, Gültekin S, Huber J, Bileck A, Kreil DP, Gerner C, Jenner F.

Dis Model Mech. 2018 Jul 6;11(7). pii: dmm033092. doi: 10.1242/dmm.033092.


A carcinogenic trigger to study the function of tumor suppressor genes in Schmidtea mediterranea.

Van Roten A, Barakat AZA, Wouters A, Tran TA, Mouton S, Noben JP, Gentile L, Smeets K.

Dis Model Mech. 2018 Jul 2. pii: dmm.032573. doi: 10.1242/dmm.032573. [Epub ahead of print]


Hypoxia-inducible factor-1 (HIF-1) activation in myeloid cells accelerates DSS-induced colitis progression in mice.

Kim YE, Lee M, Gu H, Kim J, Jeong S, Yeo S, Lee YJ, Im SH, Sung YC, Kim HJ, Weissman IL, Ahn GO.

Dis Model Mech. 2018 Jul 2. pii: dmm.033241. doi: 10.1242/dmm.033241. [Epub ahead of print]


Retina-specific loss of Ikbkap/Elp1 causes mitochondrial dysfunction that leads to selective retinal ganglion cell degeneration in a mouse model of familial dysautonomia.

Ueki Y, Shchepetkina V, Lefcort F.

Dis Model Mech. 2018 Jun 21. pii: dmm.033746. doi: 10.1242/dmm.033746. [Epub ahead of print]


PGC-1α repression and high fat diet induce age-related macular degeneration-like phenotypes in mice.

Zhang M, Chu Y, Mowery J, Konkel B, Galli S, Theos AC, Golestaneh N.

Dis Model Mech. 2018 Jun 20. pii: dmm.032698. doi: 10.1242/dmm.032698. [Epub ahead of print]


Octopamine-signaling in the metazoan pathogen, Schistosoma mansoni: localization, small-molecule screening and opportunities for drug development.

El-Sakkary N, Chen S, Arkin MR, Caffrey CR, Ribeiro P.

Dis Model Mech. 2018 Jul 9. pii: dmm.033563. doi: 10.1242/dmm.033563. [Epub ahead of print]


Impaired β-cell glucokinase as an underlying mechanism in diet-induced diabetes.

Lu B, Kurmi K, Munoz-Gomez M, Jacobus Ambuludi EJ, Tonne JM, Rakshit K, Hitosugi T, Kudva YC, Matveyenko AV, Ikeda Y.

Dis Model Mech. 2018 Jun 13;11(6). pii: dmm033316. doi: 10.1242/dmm.033316.


Epigenetic regulators Rbbp4 and Hdac1 are overexpressed in a zebrafish model of RB1 embryonal brain tumor, and are required for neural progenitor survival and proliferation.

Schultz LE, Haltom JA, Almeida MP, Wierson WA, Solin SL, Weiss TJ, Helmer JA, Sandquist EJ, Shive HR, McGrail M.

Dis Model Mech. 2018 Jun 15;11(6). pii: dmm034124. doi: 10.1242/dmm.034124.


Transcriptional upregulation of Bag3, a chaperone-assisted selective autophagy factor, in animal models of KY-deficient hereditary myopathy.

Jokl EJ, Hughes GL, Cracknell T, Pownall ME, Blanco G.

Dis Model Mech. 2018 Jul 6;11(7). pii: dmm033225. doi: 10.1242/dmm.033225.


Tracking progress: an update on animal models for Duchenne muscular dystrophy.

Wells DJ.

Dis Model Mech. 2018 Jun 13;11(6). pii: dmm035774. doi: 10.1242/dmm.035774.


Orthotopic and heterotopic murine models of pancreatic cancer and their different responses to FOLFIRINOX chemotherapy.

Erstad DJ, Sojoodi M, Taylor MS, Ghoshal S, Razavi AA, Graham-O'Regan KA, Bardeesy N, Ferrone CR, Lanuti M, Caravan P, Tanabe KK, Fuchs BC.

Dis Model Mech. 2018 Jun 14. pii: dmm.034793. doi: 10.1242/dmm.034793. [Epub ahead of print]


Recapitulating muscle disease phenotypes with myotonic dystrophy 1 iPS cells: a tool for disease modeling and drug discovery.

Mondragon-Gonzalez R, Perlingeiro RCR.

Dis Model Mech. 2018 Jun 13. pii: dmm.034728. doi: 10.1242/dmm.034728. [Epub ahead of print]


Identification of cardioprotective drugs by medium-scale in vivo pharmacological screening on a Drosophila cardiac model of Friedreich's ataxia.

Palandri A, Martin E, Russi M, Rera M, Tricoire H, Monnier V.

Dis Model Mech. 2018 Jun 13. pii: dmm.033811. doi: 10.1242/dmm.033811. [Epub ahead of print]


Cerebellar synapse properties and cerebellum-dependent motor and non-motor performance in Dp71-null mice.

Helleringer R, Le Verger D, Li X, Izabelle C, Chaussenot R, Belmaati-Cherkaoui M, Dammak R, Decottignies P, Daniel H, Galante M, Vaillend C.

Dis Model Mech. 2018 Jul 10;11(7). pii: dmm033258. doi: 10.1242/dmm.033258.

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