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Items: 1 to 20 of 1167

1.

Site-directed mutagenesis: role of lid region for T1 lipase specificity.

Mohamed RA, Salleh AB, Leow TC, Yahaya NM, Abdul Rahman MB.

Protein Eng Des Sel. 2018 Sep 20. doi: 10.1093/protein/gzy023. [Epub ahead of print]

PMID:
30239965
2.

New engineered phenolic biosensors based on the AraC regulatory protein.

Frei CS, Qian S, Cirino PC.

Protein Eng Des Sel. 2018 Sep 19. doi: 10.1093/protein/gzy024. [Epub ahead of print]

PMID:
30239947
3.

Rational optimization of a monoclonal antibody for simultaneous improvements in its solution properties and biological activity.

Kumar S, Roffi K, Tomar DS, Cirelli D, Luksha N, Meyer D, Mitchell J, Allen MJ, Li L.

Protein Eng Des Sel. 2018 Sep 5. doi: 10.1093/protein/gzy020. [Epub ahead of print]

PMID:
30189027
4.

Synthetic 10FN3-based mono- and bivalent inhibitors of MDM2/X function.

Lau SY, Siau JW, Sobota RM, Wang CI, Zhong P, Lane DP, Ghadessy FJ.

Protein Eng Des Sel. 2018 Aug 30. doi: 10.1093/protein/gzy018. [Epub ahead of print]

PMID:
30169723
5.

Variable heavy-variable light domain and Fab-arm CrossMabs with charged residue exchanges to enforce correct light chain assembly.

Regula JT, Imhof-Jung S, Mølhøj M, Benz J, Ehler A, Bujotzek A, Schaefer W, Klein C.

Protein Eng Des Sel. 2018 Aug 28. doi: 10.1093/protein/gzy021. [Epub ahead of print]

PMID:
30169707
6.

Analysis of nanobody paratopes reveals greater diversity than classical antibodies.

Mitchell LS, Colwell LJ.

Protein Eng Des Sel. 2018 Jul 25. doi: 10.1093/protein/gzy017. [Epub ahead of print]

PMID:
30053276
7.

De novo designed transmembrane peptides activating the α5β1 integrin.

Mravic M, Hu H, Lu Z, Bennett JS, Sanders CR, Orr AW, DeGrado WF.

Protein Eng Des Sel. 2018 Jul 10. doi: 10.1093/protein/gzy014. [Epub ahead of print]

PMID:
29992271
8.

Molecular dynamics-derived rotamer libraries for d-amino acids within homochiral and heterochiral polypeptides.

Childers MC, Towse CL, Daggett V.

Protein Eng Des Sel. 2018 Jul 10. doi: 10.1093/protein/gzy016. [Epub ahead of print]

PMID:
29992252
9.

A novel dual-cytokine-antibody fusion protein for the treatment of CD38-positive malignancies.

De Luca R, Kachel P, Kropivsek K, Snijder B, Manz MG, Neri D.

Protein Eng Des Sel. 2018 Jul 5. doi: 10.1093/protein/gzy015. [Epub ahead of print]

PMID:
29982719
10.

The structure of SALM5 suggests a dimeric assembly for the presynaptic RPTP ligand recognition.

Karki S, Paudel P, Sele C, Shkumatov AV, Kajander T.

Protein Eng Des Sel. 2018 Jun 12. doi: 10.1093/protein/gzy012. [Epub ahead of print]

PMID:
29897575
11.

Towards conformational fidelity of a quaternary HIV-1 epitope: computational design and directed evolution of a minimal V1V2 antigen.

Lai JI, Verma D, Bailey-Kellogg C, Ackerman ME.

Protein Eng Des Sel. 2018 Apr 1;31(4):121-133. doi: 10.1093/protein/gzy010.

12.

A platform for chemical modification of mandelate racemase: characterization of the C92S/C264S and γ-thialysine 166 variants.

Nagar M, Kumar H, Bearne SL.

Protein Eng Des Sel. 2018 Apr 1;31(4):135-145. doi: 10.1093/protein/gzy011.

PMID:
29850884
13.

Roles of the disulfide bond between the variable and the constant domains of rabbit immunoglobulin kappa chains in thermal stability and affinity.

Kawade R, Akiba H, Entzminger K, Maruyama T, Okumura CJ, Tsumoto K.

Protein Eng Des Sel. 2018 May 30. doi: 10.1093/protein/gzy008. [Epub ahead of print]

PMID:
29850878
14.

Lessons learned from merging wet lab experiments with molecular simulation to improve mAb humanization.

Schwaigerlehner L, Pechlaner M, Mayrhofer P, Oostenbrink C, Kunert R.

Protein Eng Des Sel. 2018 May 11. doi: 10.1093/protein/gzy009. [Epub ahead of print]

PMID:
29757445
15.

New imine-reducing enzymes from β-hydroxyacid dehydrogenases by single amino acid substitutions.

Lenz M, Fademrecht S, Sharma M, Pleiss J, Grogan G, Nestl BM.

Protein Eng Des Sel. 2018 Apr 1;31(4):109-120. doi: 10.1093/protein/gzy006.

PMID:
29733377
16.

Generation of orthogonal Fab-based trispecific antibody formats.

Wu X, Yuan R, Bacica M, Demarest SJ.

Protein Eng Des Sel. 2018 Apr 28. doi: 10.1093/protein/gzy007. [Epub ahead of print]

PMID:
29718394
17.

Creation of a formate: malate oxidoreductase by fusion of dehydrogenase enzymes with PEGylated cofactor swing arms.

Ozbakir HF, Garcia KE, Banta S.

Protein Eng Des Sel. 2018 Apr 1;31(4):103-108. doi: 10.1093/protein/gzy005.

PMID:
29660073
18.

Decreased Km to dNTPs is an essential M-MuLV reverse transcriptase adoption required to perform efficient cDNA synthesis in One-Step RT-PCR assay.

Palikša S, Alzbutas G, Skirgaila R.

Protein Eng Des Sel. 2018 Mar 1;31(3):79-89. doi: 10.1093/protein/gzy003.

PMID:
29608777
19.

Identification of high affinity HER2 binding antibodies using CHO Fab surface display.

Nguyen AW, Le KC, Maynard JA.

Protein Eng Des Sel. 2018 Mar 1;31(3):91-101. doi: 10.1093/protein/gzy004.

PMID:
29566240
20.

Affinity maturation of an TpoR targeting antibody in full-length IgG form for enhanced agonist activity.

Yang Z, Du M, Wang W, Xin X, Ma P, Zhang H, Lerner RA.

Protein Eng Des Sel. 2018 Feb 21. doi: 10.1093/protein/gzy002. [Epub ahead of print]

PMID:
29474709

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