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Items: 1 to 20 of 8477

1.

A 30-year journey from volume-regulated anion currents to molecular structure of the LRRC8 channel.

Strange K, Yamada T, Denton JS.

J Gen Physiol. 2019 Jan 16. pii: jgp.201812138. doi: 10.1085/jgp.201812138. [Epub ahead of print] Review.

PMID:
30651298
2.

Deletion of Enigma Homologue from the Z-disc slows tension development kinetics in mouse myocardium.

Gregorich ZR, Patel JR, Cai W, Lin Z, Heurer R, Fitzsimons DP, Moss RL, Ge Y.

J Gen Physiol. 2019 Jan 14. pii: jgp.201812214. doi: 10.1085/jgp.201812214. [Epub ahead of print]

PMID:
30642915
3.

A single molecular distance predicts agonist binding energy in nicotinic receptors.

Tripathy S, Zheng W, Auerbach A.

J Gen Physiol. 2019 Jan 11. pii: jgp.201812212. doi: 10.1085/jgp.201812212. [Epub ahead of print]

PMID:
30635370
4.

Efficiency measures the conversion of agonist binding energy into receptor conformational change.

Nayak TK, Vij R, Bruhova I, Shandilya J, Auerbach A.

J Gen Physiol. 2019 Jan 11. pii: jgp.201812215. doi: 10.1085/jgp.201812215. [Epub ahead of print]

PMID:
30635369
5.

SR Ca2+ leak in skeletal muscle fibers acts as an intracellular signal to increase fatigue resistance.

Ivarsson N, Mattsson CM, Cheng AJ, Bruton JD, Ekblom B, Lanner JT, Westerblad H.

J Gen Physiol. 2019 Jan 11. pii: jgp.201812152. doi: 10.1085/jgp.201812152. [Epub ahead of print]

PMID:
30635368
6.

Models to determine the kinetic mechanisms of ion-coupled transporters.

Lolkema JS, Slotboom DJ.

J Gen Physiol. 2019 Jan 10. pii: jgp.201812055. doi: 10.1085/jgp.201812055. [Epub ahead of print]

PMID:
30630873
7.

Investigating an epileptogenic mutation.

Sedwick C.

J Gen Physiol. 2019 Jan 9. pii: jgp.201812316. doi: 10.1085/jgp.201812316. [Epub ahead of print]

PMID:
30626616
8.

Organization of ATP-gated P2X1 receptor intracellular termini in apo and desensitized states.

Fryatt AG, Dayl S, Stavrou A, Schmid R, Evans RJ.

J Gen Physiol. 2019 Jan 9. pii: jgp.201812108. doi: 10.1085/jgp.201812108. [Epub ahead of print]

PMID:
30626615
9.

Noncompetitive antagonists induce cooperative AMPA receptor channel gating.

Shi EY, Yuan CL, Sipple MT, Srinivasan J, Ptak CP, Oswald RE, Nowak LM.

J Gen Physiol. 2019 Jan 8. pii: jgp.201812209. doi: 10.1085/jgp.201812209. [Epub ahead of print]

PMID:
30622133
10.

Reinterpretation of the substrate specificity of the voltage-sensing phosphatase during dimerization.

Kruse M, Kohout SC, Hille B.

J Gen Physiol. 2019 Jan 8. pii: jgp.201812260. doi: 10.1085/jgp.201812260. [Epub ahead of print]

PMID:
30622132
11.

Methodological improvements for fluorescence recordings in Xenopus laevis oocytes.

Lee EEL, Bezanilla F.

J Gen Physiol. 2019 Jan 3. pii: jgp.201812189. doi: 10.1085/jgp.201812189. [Epub ahead of print]

PMID:
30606741
12.

Developmental increase in β-MHC enhances sarcomere length-dependent activation in the myocardium.

Reda SM, Gollapudi SK, Chandra M.

J Gen Physiol. 2019 Jan 2. pii: jgp.201812183. doi: 10.1085/jgp.201812183. [Epub ahead of print]

PMID:
30602626
13.

Batrachotoxin acts as a stent to hold open homotetrameric prokaryotic voltage-gated sodium channels.

Finol-Urdaneta RK, McArthur JR, Goldschen-Ohm MP, Gaudet R, Tikhonov DB, Zhorov BS, French RJ.

J Gen Physiol. 2018 Dec 26. pii: jgp.201812278. doi: 10.1085/jgp.201812278. [Epub ahead of print]

PMID:
30587506
14.

Epilepsy-associated mutations in the voltage sensor of KCNQ3 affect voltage dependence of channel opening.

Barro-Soria R.

J Gen Physiol. 2018 Dec 21. pii: jgp.201812221. doi: 10.1085/jgp.201812221. [Epub ahead of print]

PMID:
30578330
15.

Toward an understanding of the regulation of myofibrillar function.

Moss RL, de Tombe PP, Solaro RJ.

J Gen Physiol. 2019 Jan 7;151(1):1-2. doi: 10.1085/jgp.201812288. Epub 2018 Dec 21. No abstract available.

PMID:
30578329
16.

The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM.

Piroddi N, Witjas-Paalberends ER, Ferrara C, Ferrantini C, Vitale G, Scellini B, Wijnker PJM, Sequiera V, Dooijes D, Dos Remedios C, Schlossarek S, Leung MC, Messer A, Ward DG, Biggeri A, Tesi C, Carrier L, Redwood CS, Marston SB, van der Velden J, Poggesi C.

J Gen Physiol. 2019 Jan 7;151(1):18-29. doi: 10.1085/jgp.201812160. Epub 2018 Dec 21.

PMID:
30578328
17.

How a mutation undermines cardiac function.

Sedwick C.

J Gen Physiol. 2019 Jan 7;151(1):3. doi: 10.1085/jgp.201812302. Epub 2018 Dec 21.

PMID:
30578327
18.

Recovery of left ventricular function following in vivo reexpression of cardiac myosin binding protein C.

Giles J, Patel JR, Miller A, Iverson E, Fitzsimons D, Moss RL.

J Gen Physiol. 2019 Jan 7;151(1):77-89. doi: 10.1085/jgp.201812238. Epub 2018 Dec 20.

PMID:
30573635
19.

Metformin improves diastolic function in an HFpEF-like mouse model by increasing titin compliance.

Slater RE, Strom JG, Methawasin M, Liss M, Gotthardt M, Sweitzer N, Granzier HL.

J Gen Physiol. 2019 Jan 7;151(1):42-52. doi: 10.1085/jgp.201812259. Epub 2018 Dec 19.

20.

Unlocking the gating mechanism of Kv2.1 using guangxitoxin.

Navarro MA, Milescu LS, Milescu M.

J Gen Physiol. 2018 Dec 18. pii: jgp.201812254. doi: 10.1085/jgp.201812254. [Epub ahead of print] No abstract available.

PMID:
30563879

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