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Items: 1 to 50 of 87

1.

Altered proteome of high-density lipoproteins from paediatric acute lymphoblastic leukemia survivors.

Fournier M, Bonneil E, Garofalo C, Grimard G, Laverdière C, Krajinovic M, Drouin S, Sinnett D, Marcil V, Levy E.

Sci Rep. 2019 Mar 12;9(1):4268. doi: 10.1038/s41598-019-40906-x.

2.

Doxorubicin treatments induce significant changes on the cardiac autonomic nervous system in childhood acute lymphoblastic leukemia long-term survivors.

Caru M, Corbin D, Périé D, Lemay V, Delfrate J, Drouin S, Bertout L, Krajinovic M, Laverdière C, Andelfinger G, Sinnett D, Curnier D.

Clin Res Cardiol. 2019 Feb 18. doi: 10.1007/s00392-019-01427-9. [Epub ahead of print]

PMID:
30778669
3.

Prevention of Long-term Adverse Health Outcomes With Cardiorespiratory Fitness and Physical Activity in Childhood Acute Lymphoblastic Leukemia Survivors.

Lemay V, Caru M, Samoilenko M, Drouin S, Alos N, Lefebvre G, Levy E, Lippé S, Marcil V, Sultan S, Bertout L, Krajinovic M, Laverdière C, Raboisson MJ, Sinnett D, Andelfinger G, Curnier D.

J Pediatr Hematol Oncol. 2019 Jan 25. doi: 10.1097/MPH.0000000000001426. [Epub ahead of print]

PMID:
30688830
4.

Very long intergenic non-coding RNA transcripts and expression profiles are associated to specific childhood acute lymphoblastic leukemia subtypes.

Caron M, St-Onge P, Drouin S, Richer C, Sontag T, Busche S, Bourque G, Pastinen T, Sinnett D.

PLoS One. 2018 Nov 15;13(11):e0207250. doi: 10.1371/journal.pone.0207250. eCollection 2018.

5.

Genome wide mapping of ETV6 binding sites in pre-B leukemic cells.

Neveu B, Caron M, Lagacé K, Richer C, Sinnett D.

Sci Rep. 2018 Oct 19;8(1):15526. doi: 10.1038/s41598-018-33947-1.

6.

Cancer-related effects on relationships, long-term psychological status and relationship satisfaction in couples whose child was treated for leukemia: A PETALE study.

Burns W, Péloquin K, Rondeau É, Drouin S, Bertout L, Lacoste-Julien A, Krajinovic M, Laverdière C, Sinnett D, Sultan S.

PLoS One. 2018 Sep 7;13(9):e0203435. doi: 10.1371/journal.pone.0203435. eCollection 2018.

7.

Genetic risk factors for VIPN in childhood acute lymphoblastic leukemia patients identified using whole-exome sequencing.

Abaji R, Ceppi F, Patel S, Gagné V, Xu CJ, Spinella JF, Colombini A, Parasole R, Buldini B, Basso G, Conter V, Cazzaniga G, Leclerc JM, Laverdière C, Sinnett D, Krajinovic M.

Pharmacogenomics. 2018 Oct;19(15):1181-1193. doi: 10.2217/pgs-2018-0093. Epub 2018 Sep 7.

PMID:
30191766
8.

Psychological risk in long-term survivors of childhood acute lymphoblastic leukemia and its association with functional health status: A PETALE cohort study.

Anestin AS, Lippé S, Robaey P, Bertout L, Drouin S, Krajinovic M, Michon B, Rondeau É, Samoilenko M, Laverdière C, Sinnett D, Sultan S.

Pediatr Blood Cancer. 2018 Nov;65(11):e27356. doi: 10.1002/pbc.27356. Epub 2018 Aug 7.

PMID:
30084222
9.

Development and relative validation of a food frequency questionnaire for French-Canadian adolescent and young adult survivors of acute lymphoblastic leukemia.

Morel S, Portolese O, Chertouk Y, Leahy J, Bertout L, Laverdière C, Krajinovic M, Sinnett D, Levy E, Marcil V.

Nutr J. 2018 Apr 21;17(1):45. doi: 10.1186/s12937-018-0355-9.

10.

Insight from mitochondrial functions and proteomics to understand cardiometabolic disorders in survivors of acute lymphoblastic leukemia.

Leahy J, Spahis S, Bonneil E, Garofalo C, Grimard G, Morel S, Laverdière C, Krajinovic M, Drouin S, Delvin E, Sinnett D, Marcil V, Levy E.

Metabolism. 2018 Aug;85:151-160. doi: 10.1016/j.metabol.2018.03.011. Epub 2018 Mar 18.

PMID:
29563052
11.

Vitamin D nutritional status and bone turnover markers in childhood acute lymphoblastic leukemia survivors: A PETALE study.

Delvin E, Alos N, Rauch F, Marcil V, Morel S, Boisvert M, Lecours MA, Laverdière C, Sinnett D, Krajinovic M, Dubois J, Drouin S, Lefebvre G, Samoilenko M, Nyalendo C, Cavalier E, Levy E.

Clin Nutr. 2019 Apr;38(2):912-919. doi: 10.1016/j.clnu.2018.02.006. Epub 2018 Feb 21.

PMID:
29503055
12.

Mutational dynamics of early and late relapsed childhood ALL: rapid clonal expansion and long-term dormancy.

Spinella JF, Richer C, Cassart P, Ouimet M, Healy J, Sinnett D.

Blood Adv. 2018 Feb 13;2(3):177-188. doi: 10.1182/bloodadvances.2017011510.

13.

Influence of BCL2L11 polymorphism on osteonecrosis during treatment of childhood acute lymphoblastic leukemia.

Plesa M, Gagné V, Glisovic S, Younan M, Sharif-Askari B, Laverdière C, Alos N, Leclerc JM, Sallan SE, Neuberg D, Kutok JL, Silverman LB, Sinnett D, Krajinovic M.

Pharmacogenomics J. 2019 Feb;19(1):33-41. doi: 10.1038/s41397-017-0002-4. Epub 2017 Dec 27.

PMID:
29282361
14.

Cardiometabolic Risk Factors in Childhood, Adolescent and Young Adult Survivors of Acute Lymphoblastic Leukemia - A Petale Cohort.

Levy E, Samoilenko M, Morel S, England J, Amre D, Bertout L, Drouin S, Laverdière C, Krajinovic M, Sinnett D, Lefebvre G, Marcil V.

Sci Rep. 2017 Dec 15;7(1):17684. doi: 10.1038/s41598-017-17716-0.

15.

Tracking Silent Hypersensitivity Reactions to Asparaginase during Leukemia Therapy Using Single-Chip Indirect Plasmonic and Fluorescence Immunosensing.

Charbonneau DM, Breault-Turcot J, Sinnett D, Krajinovic M, Leclerc JM, Masson JF, Pelletier JN.

ACS Sens. 2017 Dec 22;2(12):1761-1766. doi: 10.1021/acssensors.7b00584. Epub 2017 Dec 4.

PMID:
29168384
16.

Genomic determinants of long-term cardiometabolic complications in childhood acute lymphoblastic leukemia survivors.

England J, Drouin S, Beaulieu P, St-Onge P, Krajinovic M, Laverdière C, Levy E, Marcil V, Sinnett D.

BMC Cancer. 2017 Nov 10;17(1):751. doi: 10.1186/s12885-017-3722-6.

17.

LncRNAs downregulated in childhood acute lymphoblastic leukemia modulate apoptosis, cell migration, and DNA damage response.

Gioia R, Drouin S, Ouimet M, Caron M, St-Onge P, Richer C, Sinnett D.

Oncotarget. 2017 Sep 11;8(46):80645-80650. doi: 10.18632/oncotarget.20817. eCollection 2017 Oct 6.

18.

How to interpret high levels of distress when using the Distress Thermometer in the long-term follow-up clinic? A study with Acute Lymphoblastic Leukemia survivors.

Pépin AJ, Lippé S, Krajinovic M, Laverdière C, Michon B, Sinnett D, Sultan S.

Pediatr Hematol Oncol. 2017 Apr;34(3):133-137. doi: 10.1080/08880018.2017.1338805. Epub 2017 Sep 18.

PMID:
28922050
19.

Novel therapy for childhood acute lymphoblastic leukemia.

Santiago R, Vairy S, Sinnett D, Krajinovic M, Bittencourt H.

Expert Opin Pharmacother. 2017 Aug;18(11):1081-1099. doi: 10.1080/14656566.2017.1340938. Epub 2017 Jun 26. Review.

PMID:
28608730
20.

Whole-exome sequencing identified genetic risk factors for asparaginase-related complications in childhood ALL patients.

Abaji R, Gagné V, Xu CJ, Spinella JF, Ceppi F, Laverdière C, Leclerc JM, Sallan SE, Neuberg D, Kutok JL, Silverman LB, Sinnett D, Krajinovic M.

Oncotarget. 2017 Jul 4;8(27):43752-43767. doi: 10.18632/oncotarget.17959.

21.

Specific expression of novel long non-coding RNAs in high-hyperdiploid childhood acute lymphoblastic leukemia.

Lajoie M, Drouin S, Caron M, St-Onge P, Ouimet M, Gioia R, Lafond MH, Vidal R, Richer C, Oualkacha K, Droit A, Sinnett D.

PLoS One. 2017 Mar 27;12(3):e0174124. doi: 10.1371/journal.pone.0174124. eCollection 2017.

22.

Lipid and lipoprotein abnormalities in acute lymphoblastic leukemia survivors.

Morel S, Leahy J, Fournier M, Lamarche B, Garofalo C, Grimard G, Poulain F, Delvin E, Laverdière C, Krajinovic M, Drouin S, Sinnett D, Marcil V, Levy E.

J Lipid Res. 2017 May;58(5):982-993. doi: 10.1194/jlr.M072207. Epub 2017 Mar 8.

23.

A childhood acute lymphoblastic leukemia-specific lncRNA implicated in prednisolone resistance, cell proliferation, and migration.

Ouimet M, Drouin S, Lajoie M, Caron M, St-Onge P, Gioia R, Richer C, Sinnett D.

Oncotarget. 2017 Jan 31;8(5):7477-7488. doi: 10.18632/oncotarget.13936.

24.

Polymorphisms of ABCC5 and NOS3 genes influence doxorubicin cardiotoxicity in survivors of childhood acute lymphoblastic leukemia.

Krajinovic M, Elbared J, Drouin S, Bertout L, Rezgui A, Ansari M, Raboisson MJ, Lipshultz SE, Silverman LB, Sallan SE, Neuberg DS, Kutok JL, Laverdière C, Sinnett D, Andelfinger G.

Pharmacogenomics J. 2017 Jan;17(1):107. doi: 10.1038/tpj.2016.86. Epub 2016 Dec 13. No abstract available.

PMID:
27958382
25.

The PETALE study: Late adverse effects and biomarkers in childhood acute lymphoblastic leukemia survivors.

Marcoux S, Drouin S, Laverdière C, Alos N, Andelfinger GU, Bertout L, Curnier D, Friedrich MG, Kritikou EA, Lefebvre G, Levy E, Lippé S, Marcil V, Raboisson MJ, Rauch F, Robaey P, Samoilenko M, Séguin C, Sultan S, Krajinovic M, Sinnett D.

Pediatr Blood Cancer. 2017 Jun;64(6). doi: 10.1002/pbc.26361. Epub 2016 Dec 4.

PMID:
27917589
26.

SNooPer: a machine learning-based method for somatic variant identification from low-pass next-generation sequencing.

Spinella JF, Mehanna P, Vidal R, Saillour V, Cassart P, Richer C, Ouimet M, Healy J, Sinnett D.

BMC Genomics. 2016 Nov 14;17(1):912.

27.

Adverse neuropsychological effects associated with cumulative doses of corticosteroids to treat childhood acute lymphoblastic leukemia: A literature review.

Pépin AJ, Cloutier-Bergeron A, Malboeuf-Hurtubise C, Achille M, Krajinovic M, Laverdière C, Lippé S, Marcoux S, Sinnett D, Sultan S.

Crit Rev Oncol Hematol. 2016 Nov;107:138-148. doi: 10.1016/j.critrevonc.2016.09.001. Epub 2016 Sep 9. Review.

PMID:
27823641
28.

Genome-wide repression of eRNA and target gene loci by the ETV6-RUNX1 fusion in acute leukemia.

Teppo S, Laukkanen S, Liuksiala T, Nordlund J, Oittinen M, Teittinen K, Grönroos T, St-Onge P, Sinnett D, Syvänen AC, Nykter M, Viiri K, Heinäniemi M, Lohi O.

Genome Res. 2016 Nov;26(11):1468-1477. Epub 2016 Sep 12.

29.

CLIC5: a novel ETV6 target gene in childhood acute lymphoblastic leukemia.

Neveu B, Spinella JF, Richer C, Lagacé K, Cassart P, Lajoie M, Jananji S, Drouin S, Healy J, Hickson GR, Sinnett D.

Haematologica. 2016 Dec;101(12):1534-1543. Epub 2016 Aug 18.

30.

Polymorphisms of ABCC5 and NOS3 genes influence doxorubicin cardiotoxicity in survivors of childhood acute lymphoblastic leukemia.

Krajinovic M, Elbared J, Drouin S, Bertout L, Rezgui A, Ansari M, Raboisson MJ, Lipshultz SE, Silverman LB, Sallan SE, Neuberg DS, Kutok JL, Laverdière C, Sinnett D, Andelfinger G.

Pharmacogenomics J. 2016 Nov;16(6):530-535. doi: 10.1038/tpj.2015.63. Epub 2015 Sep 8.

PMID:
26345518
31.

A novel somatic mutation in ACD induces telomere lengthening and apoptosis resistance in leukemia cells.

Spinella JF, Cassart P, Garnier N, Rousseau P, Drullion C, Richer C, Ouimet M, Saillour V, Healy J, Autexier C, Sinnett D.

BMC Cancer. 2015 Sep 7;15:621. doi: 10.1186/s12885-015-1639-5.

32.

Whole-exome sequencing of a rare case of familial childhood acute lymphoblastic leukemia reveals putative predisposing mutations in Fanconi anemia genes.

Spinella JF, Healy J, Saillour V, Richer C, Cassart P, Ouimet M, Sinnett D.

BMC Cancer. 2015 Jul 23;15:539. doi: 10.1186/s12885-015-1549-6.

33.

Association between CEBPE Variant and Childhood Acute Leukemia Risk: Evidence from a Meta-Analysis of 22 Studies.

Sun J, Zheng J, Tang L, Healy J, Sinnett D, Dai YE.

PLoS One. 2015 May 4;10(5):e0125657. doi: 10.1371/journal.pone.0125657. eCollection 2015.

34.

Contribution of polymorphisms in IKZF1 gene to childhood acute leukemia: a meta-analysis of 33 case-control studies.

Dai YE, Tang L, Healy J, Sinnett D.

PLoS One. 2014 Nov 25;9(11):e113748. doi: 10.1371/journal.pone.0113748. eCollection 2014.

35.

Polymorphisms of the vincristine pathway and response to treatment in children with childhood acute lymphoblastic leukemia.

Ceppi F, Langlois-Pelletier C, Gagné V, Rousseau J, Ciolino C, De Lorenzo S, Kevin KM, Cijov D, Sallan SE, Silverman LB, Neuberg D, Kutok JL, Sinnett D, Laverdière C, Krajinovic M.

Pharmacogenomics. 2014 Jun;15(8):1105-16. doi: 10.2217/pgs.14.68.

36.

Polymorphisms of asparaginase pathway and asparaginase-related complications in children with acute lymphoblastic leukemia.

Ben Tanfous M, Sharif-Askari B, Ceppi F, Laaribi H, Gagné V, Rousseau J, Labuda M, Silverman LB, Sallan SE, Neuberg D, Kutok JL, Sinnett D, Laverdière C, Krajinovic M.

Clin Cancer Res. 2015 Jan 15;21(2):329-34. doi: 10.1158/1078-0432.CCR-14-0508. Epub 2014 Jun 6.

37.

Pharmacogenetic considerations for acute lymphoblastic leukemia therapies.

Dulucq S, Laverdière C, Sinnett D, Krajinovic M.

Expert Opin Drug Metab Toxicol. 2014 May;10(5):699-719. doi: 10.1517/17425255.2014.893294. Epub 2014 Mar 27. Review.

PMID:
24673379
38.

Impact of promoter polymorphisms in key regulators of the intrinsic apoptosis pathway on the outcome of childhood acute lymphoblastic leukemia.

Sanchez R, St-Cyr J, Lalonde ME, Healy J, Richer C, Gagné V, Laverdière C, Silverman LB, Sallan SE, Neuberg D, Kutok JL, Kritikou EA, Krajinovic M, Sinnett D.

Haematologica. 2014 Feb;99(2):314-21. doi: 10.3324/haematol.2013.085340. Epub 2013 Sep 13.

39.

Bim polymorphisms: influence on function and response to treatment in children with acute lymphoblastic leukemia.

Gagné V, Rousseau J, Labuda M, Sharif-Askari B, Brukner I, Laverdière C, Ceppi F, Sallan SE, Silverman LB, Neuberg D, Kutok JL, Sinnett D, Krajinovic M.

Clin Cancer Res. 2013 Sep 15;19(18):5240-9. doi: 10.1158/1078-0432.CCR-13-1215. Epub 2013 Aug 1. Erratum in: Clin Cancer Res. 2014 Aug 15;20(16):4415.

40.

Joint genotype inference with germline and somatic mutations.

Bareke E, Saillour V, Spinella JF, Vidal R, Healy J, Sinnett D, Csűrös M.

BMC Bioinformatics. 2013;14 Suppl 5:S3. doi: 10.1186/1471-2105-14-S5-S3. Epub 2013 Apr 10.

41.

Integration of high-resolution methylome and transcriptome analyses to dissect epigenomic changes in childhood acute lymphoblastic leukemia.

Busche S, Ge B, Vidal R, Spinella JF, Saillour V, Richer C, Healy J, Chen SH, Droit A, Sinnett D, Pastinen T.

Cancer Res. 2013 Jul 15;73(14):4323-36. doi: 10.1158/0008-5472.CAN-12-4367. Epub 2013 May 30.

42.

Role of NOS3 DNA variants in externalizing behavioral problems observed in childhood leukemia survivors.

Marcoux S, Robaey P, Gahier A, Labuda M, Rousseau J, Sinnett D, Moghrabi A, Laverdière C, Krajinovic M.

J Pediatr Hematol Oncol. 2013 May;35(4):e157-62. doi: 10.1097/MPH.0b013e31828e518d.

PMID:
23612386
43.

The Childhood Leukemia International Consortium.

Metayer C, Milne E, Clavel J, Infante-Rivard C, Petridou E, Taylor M, Schüz J, Spector LG, Dockerty JD, Magnani C, Pombo-de-Oliveira MS, Sinnett D, Murphy M, Roman E, Monge P, Ezzat S, Mueller BA, Scheurer ME, Armstrong BK, Birch J, Kaatsch P, Koifman S, Lightfoot T, Bhatti P, Bondy ML, Rudant J, O'Neill K, Miligi L, Dessypris N, Kang AY, Buffler PA.

Cancer Epidemiol. 2013 Jun;37(3):336-47. doi: 10.1016/j.canep.2012.12.011. Epub 2013 Feb 9.

44.

Rare allelic forms of PRDM9 associated with childhood leukemogenesis.

Hussin J, Sinnett D, Casals F, Idaghdour Y, Bruat V, Saillour V, Healy J, Grenier JC, de Malliard T, Busche S, Spinella JF, Larivière M, Gibson G, Andersson A, Holmfeldt L, Ma J, Wei L, Zhang J, Andelfinger G, Downing JR, Mullighan CG, Awadalla P.

Genome Res. 2013 Mar;23(3):419-30. doi: 10.1101/gr.144188.112. Epub 2012 Dec 5.

45.

ATF5 polymorphisms influence ATF function and response to treatment in children with childhood acute lymphoblastic leukemia.

Rousseau J, Gagné V, Labuda M, Beaubois C, Sinnett D, Laverdière C, Moghrabi A, Sallan SE, Silverman LB, Neuberg D, Kutok JL, Krajinovic M.

Blood. 2011 Nov 24;118(22):5883-90. doi: 10.1182/blood-2011-05-355560. Epub 2011 Oct 4.

46.

Novel associations between activating killer-cell immunoglobulin-like receptor genes and childhood leukemia.

Almalte Z, Samarani S, Iannello A, Debbeche O, Duval M, Infante-Rivard C, Amre DK, Sinnett D, Ahmad A.

Blood. 2011 Aug 4;118(5):1323-8. doi: 10.1182/blood-2010-10-313791. Epub 2011 May 25.

47.

Polymorphism in multidrug resistance-associated protein gene 3 is associated with outcomes in childhood acute lymphoblastic leukemia.

Ansari M, Sauty G, Labuda M, Gagné V, Rousseau J, Moghrabi A, Laverdière C, Sinnett D, Krajinovic M.

Pharmacogenomics J. 2012 Oct;12(5):386-94. doi: 10.1038/tpj.2011.17. Epub 2011 May 24.

PMID:
21606946
48.

ALG: automated genotype calling of Luminex assays.

Bourgey M, Lariviere M, Richer C, Sinnett D.

PLoS One. 2011 May 6;6(5):e19368. doi: 10.1371/journal.pone.0019368.

49.

Rationale for an international consortium to study inherited genetic susceptibility to childhood acute lymphoblastic leukemia.

Sherborne AL, Hemminki K, Kumar R, Bartram CR, Stanulla M, Schrappe M, Petridou E, Semsei AF, Szalai C, Sinnett D, Krajinovic M, Healy J, Lanciotti M, Dufour C, Indaco S, El-Ghouroury EA, Sawangpanich R, Hongeng S, Pakakasama S, Gonzalez-Neira A, Ugarte EL, Leal VP, Espinoza JP, Kamel AM, Ebid GT, Radwan ER, Yalin S, Yalin E, Berkoz M, Simpson J, Roman E, Lightfoot T, Hosking FJ, Vijayakrishnan J, Greaves M, Houlston RS.

Haematologica. 2011 Jul;96(7):1049-54. doi: 10.3324/haematol.2011.040121. Epub 2011 Apr 1. Review.

50.

Detection of fetomaternal genotype associations in early-onset disorders: evaluation of different methods and their application to childhood leukemia.

Healy J, Bourgey M, Richer C, Sinnett D, Roy-Gagnon MH.

J Biomed Biotechnol. 2010;2010:369534. doi: 10.1155/2010/369534. Epub 2010 Jun 9.

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