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Items: 1 to 20 of 161


The helicase Ded1p controls use of near-cognate translation initiation codons in 5' UTRs.

Guenther UP, Weinberg DE, Zubradt MM, Tedeschi FA, Stawicki BN, Zagore LL, Brar GA, Licatalosi DD, Bartel DP, Weissman JS, Jankowsky E.

Nature. 2018 Jul;559(7712):130-134. doi: 10.1038/s41586-018-0258-0. Epub 2018 Jun 27.


A Network of Noncoding Regulatory RNAs Acts in the Mammalian Brain.

Kleaveland B, Shi CY, Stefano J, Bartel DP.

Cell. 2018 Jul 12;174(2):350-362.e17. doi: 10.1016/j.cell.2018.05.022. Epub 2018 Jun 7.


New CRISPR Mutagenesis Strategies Reveal Variation in Repair Mechanisms among Fungi.

Vyas VK, Bushkin GG, Bernstein DA, Getz MA, Sewastianik M, Barrasa MI, Bartel DP, Fink GR.

mSphere. 2018 Apr 25;3(2). pii: e00154-18. doi: 10.1128/mSphere.00154-18. Print 2018 Apr 25.


Metazoan MicroRNAs.

Bartel DP.

Cell. 2018 Mar 22;173(1):20-51. doi: 10.1016/j.cell.2018.03.006. Review.


A Seed Mismatch Enhances Argonaute2-Catalyzed Cleavage and Partially Rescues Severely Impaired Cleavage Found in Fish.

Chen GR, Sive H, Bartel DP.

Mol Cell. 2017 Dec 21;68(6):1095-1107.e5. doi: 10.1016/j.molcel.2017.11.032.


The influence of microRNAs and poly(A) tail length on endogenous mRNA-protein complexes.

Rissland OS, Subtelny AO, Wang M, Lugowski A, Nicholson B, Laver JD, Sidhu SS, Smibert CA, Lipshitz HD, Bartel DP.

Genome Biol. 2017 Oct 31;18(1):211. doi: 10.1186/s13059-017-1330-z.


Widespread Influence of 3'-End Structures on Mammalian mRNA Processing and Stability.

Wu X, Bartel DP.

Cell. 2017 May 18;169(5):905-917.e11. doi: 10.1016/j.cell.2017.04.036.


kpLogo: positional k-mer analysis reveals hidden specificity in biological sequences.

Wu X, Bartel DP.

Nucleic Acids Res. 2017 Jul 3;45(W1):W534-W538. doi: 10.1093/nar/gkx323.


Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways.

Khurana V, Peng J, Chung CY, Auluck PK, Fanning S, Tardiff DF, Bartels T, Koeva M, Eichhorn SW, Benyamini H, Lou Y, Nutter-Upham A, Baru V, Freyzon Y, Tuncbag N, Costanzo M, San Luis BJ, Schöndorf DC, Barrasa MI, Ehsani S, Sanjana N, Zhong Q, Gasser T, Bartel DP, Vidal M, Deleidi M, Boone C, Fraenkel E, Berger B, Lindquist S.

Cell Syst. 2017 Feb 22;4(2):157-170.e14. doi: 10.1016/j.cels.2016.12.011. Epub 2017 Jan 25.


Impact of MicroRNA Levels, Target-Site Complementarity, and Cooperativity on Competing Endogenous RNA-Regulated Gene Expression.

Denzler R, McGeary SE, Title AC, Agarwal V, Bartel DP, Stoffel M.

Mol Cell. 2016 Nov 3;64(3):565-579. doi: 10.1016/j.molcel.2016.09.027. Epub 2016 Oct 27.


RNA G-quadruplexes are globally unfolded in eukaryotic cells and depleted in bacteria.

Guo JU, Bartel DP.

Science. 2016 Sep 23;353(6306). pii: aaf5371.


mRNA poly(A)-tail changes specified by deadenylation broadly reshape translation in Drosophila oocytes and early embryos.

Eichhorn SW, Subtelny AO, Kronja I, Kwasnieski JC, Orr-Weaver TL, Bartel DP.

Elife. 2016 Jul 30;5. pii: e16955. doi: 10.7554/eLife.16955.


Improved Ribosome-Footprint and mRNA Measurements Provide Insights into Dynamics and Regulation of Yeast Translation.

Weinberg DE, Shah P, Eichhorn SW, Hussmann JA, Plotkin JB, Bartel DP.

Cell Rep. 2016 Feb 23;14(7):1787-1799. doi: 10.1016/j.celrep.2016.01.043. Epub 2016 Feb 11.


The Menu of Features that Define Primary MicroRNAs and Enable De Novo Design of MicroRNA Genes.

Fang W, Bartel DP.

Mol Cell. 2015 Oct 1;60(1):131-45. doi: 10.1016/j.molcel.2015.08.015. Epub 2015 Sep 24.


Independent regulation of vertebral number and vertebral identity by microRNA-196 paralogs.

Wong SF, Agarwal V, Mansfield JH, Denans N, Schwartz MG, Prosser HM, Pourquié O, Bartel DP, Tabin CJ, McGlinn E.

Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):E4884-93. doi: 10.1073/pnas.1512655112. Epub 2015 Aug 17.


Predicting effective microRNA target sites in mammalian mRNAs.

Agarwal V, Bell GW, Nam JW, Bartel DP.

Elife. 2015 Aug 12;4. doi: 10.7554/eLife.05005.


Principles of long noncoding RNA evolution derived from direct comparison of transcriptomes in 17 species.

Hezroni H, Koppstein D, Schwartz MG, Avrutin A, Bartel DP, Ulitsky I.

Cell Rep. 2015 May 19;11(7):1110-22. doi: 10.1016/j.celrep.2015.04.023. Epub 2015 May 7.


Sequencing the cap-snatching repertoire of H1N1 influenza provides insight into the mechanism of viral transcription initiation.

Koppstein D, Ashour J, Bartel DP.

Nucleic Acids Res. 2015 May 26;43(10):5052-64. doi: 10.1093/nar/gkv333. Epub 2015 Apr 21.


mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues.

Eichhorn SW, Guo H, McGeary SE, Rodriguez-Mias RA, Shin C, Baek D, Hsu SH, Ghoshal K, Villén J, Bartel DP.

Mol Cell. 2014 Oct 2;56(1):104-15. doi: 10.1016/j.molcel.2014.08.028. Epub 2014 Sep 25.


Expanded identification and characterization of mammalian circular RNAs.

Guo JU, Agarwal V, Guo H, Bartel DP.

Genome Biol. 2014 Jul 29;15(7):409. doi: 10.1186/s13059-014-0409-z.

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