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Items: 1 to 20 of 343

1.

Dihydropyrimidine-thiones and clioquinol synergize to target β-amyloid cellular pathologies through a metal-dependent mechanism.

Tardiff DF, Brown LE, Yan X, Trilles R, Jui NT, Barrasa MI, Caldwell KA, Caldwell GA, Schaus SE, Lindquist S.

ACS Chem Neurosci. 2017 Jun 19. doi: 10.1021/acschemneuro.7b00187. [Epub ahead of print]

PMID:
28628299
2.

Combining DNP NMR with segmental and specific labeling to study a yeast prion protein strain that is not parallel in-register.

Frederick KK, Michaelis VK, Caporini MA, Andreas LB, Debelouchina GT, Griffin RG, Lindquist S.

Proc Natl Acad Sci U S A. 2017 Apr 4;114(14):3642-3647. doi: 10.1073/pnas.1619051114. Epub 2017 Mar 22.

3.

HSP90 Shapes the Consequences of Human Genetic Variation.

Karras GI, Yi S, Sahni N, Fischer M, Xie J, Vidal M, D'Andrea AD, Whitesell L, Lindquist S.

Cell. 2017 Feb 23;168(5):856-866.e12. doi: 10.1016/j.cell.2017.01.023. Epub 2017 Feb 16.

PMID:
28215707
4.

In Situ Peroxidase Labeling and Mass-Spectrometry Connects Alpha-Synuclein Directly to Endocytic Trafficking and mRNA Metabolism in Neurons.

Chung CY, Khurana V, Yi S, Sahni N, Loh KH, Auluck PK, Baru V, Udeshi ND, Freyzon Y, Carr SA, Hill DE, Vidal M, Ting AY, Lindquist S.

Cell Syst. 2017 Feb 22;4(2):242-250.e4. doi: 10.1016/j.cels.2017.01.002. Epub 2017 Jan 25.

PMID:
28131823
5.

Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways.

Khurana V, Peng J, Chung CY, Auluck PK, Fanning S, Tardiff DF, Bartels T, Koeva M, Eichhorn SW, Benyamini H, Lou Y, Nutter-Upham A, Baru V, Freyzon Y, Tuncbag N, Costanzo M, San Luis BJ, Schöndorf DC, Barrasa MI, Ehsani S, Sanjana N, Zhong Q, Gasser T, Bartel DP, Vidal M, Deleidi M, Boone C, Fraenkel E, Berger B, Lindquist S.

Cell Syst. 2017 Feb 22;4(2):157-170.e14. doi: 10.1016/j.cels.2016.12.011. Epub 2017 Jan 25.

6.

Suppression of 19S proteasome subunits marks emergence of an altered cell state in diverse cancers.

Tsvetkov P, Sokol E, Jin D, Brune Z, Thiru P, Ghandi M, Garraway LA, Gupta PB, Santagata S, Whitesell L, Lindquist S.

Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):382-387. doi: 10.1073/pnas.1619067114. Epub 2016 Dec 27.

PMID:
28028240
7.

Susan Lee Lindquist (1949-2016).

Shorter J, Gitler AD.

Nature. 2016 Nov 30;540(7631):40. doi: 10.1038/540040a. No abstract available.

PMID:
27905439
8.

Long-term functional outcomes after radical cystectomy with ileal bladder substitute: does the definition of continence matter?

Liedberg F, Ahlgren G, Baseckas G, Gudjonsson S, Håkansson U, Lindquist S, Löfgren A, Patschan O, Siller C, Sjödahl G.

Scand J Urol. 2017 Feb;51(1):44-49. doi: 10.1080/21681805.2016.1249943. Epub 2016 Nov 11.

PMID:
27834115
9.

Scarless Gene Tagging with One-Step Transformation and Two-Step Selection in Saccharomyces cerevisiae and Schizosaccharomyces pombe.

Landgraf D, Huh D, Hallacli E, Lindquist S.

PLoS One. 2016 Oct 13;11(10):e0163950. doi: 10.1371/journal.pone.0163950. eCollection 2016.

10.

Intrinsically Disordered Proteins Drive Emergence and Inheritance of Biological Traits.

Chakrabortee S, Byers JS, Jones S, Garcia DM, Bhullar B, Chang A, She R, Lee L, Fremin B, Lindquist S, Jarosz DF.

Cell. 2016 Oct 6;167(2):369-381.e12. doi: 10.1016/j.cell.2016.09.017. Epub 2016 Sep 29.

11.

A Fungal-Selective Cytochrome bc1 Inhibitor Impairs Virulence and Prevents the Evolution of Drug Resistance.

Vincent BM, Langlois JB, Srinivas R, Lancaster AK, Scherz-Shouval R, Whitesell L, Tidor B, Buchwald SL, Lindquist S.

Cell Chem Biol. 2016 Aug 18;23(8):978-991. doi: 10.1016/j.chembiol.2016.06.016. Epub 2016 Aug 11.

PMID:
27524297
12.

Clinical manifestations of intermediate allele carriers in Huntington disease.

Cubo E, Ramos-Arroyo MA, Martinez-Horta S, Martínez-Descalls A, Calvo S, Gil-Polo C; European HD Network.

Neurology. 2016 Aug 9;87(6):571-8. doi: 10.1212/WNL.0000000000002944. Epub 2016 Jul 8.

PMID:
27402890
13.

Possible Zika Virus Infection Among Pregnant Women - United States and Territories, May 2016.

Simeone RM, Shapiro-Mendoza CK, Meaney-Delman D, Petersen EE, Galang RR, Oduyebo T, Rivera-Garcia B, Valencia-Prado M, Newsome KB, Pérez-Padilla J, Williams TR, Biggerstaff M, Jamieson DJ, Honein MA; Zika and Pregnancy Working Group.

MMWR Morb Mortal Wkly Rep. 2016 May 27;65(20):514-9. doi: 10.15585/mmwr.mm6520e1.

14.

Luminidependens (LD) is an Arabidopsis protein with prion behavior.

Chakrabortee S, Kayatekin C, Newby GA, Mendillo ML, Lancaster A, Lindquist S.

Proc Natl Acad Sci U S A. 2016 May 24;113(21):6065-70. doi: 10.1073/pnas.1604478113. Epub 2016 Apr 25.

15.

An inter-species protein-protein interaction network across vast evolutionary distance.

Zhong Q, Pevzner SJ, Hao T, Wang Y, Mosca R, Menche J, Taipale M, Taşan M, Fan C, Yang X, Haley P, Murray RR, Mer F, Gebreab F, Tam S, MacWilliams A, Dricot A, Reichert P, Santhanam B, Ghamsari L, Calderwood MA, Rolland T, Charloteaux B, Lindquist S, Barabási AL, Hill DE, Aloy P, Cusick ME, Xia Y, Roth FP, Vidal M.

Mol Syst Biol. 2016 Apr 22;12(4):865. doi: 10.15252/msb.20156484.

16.

Notes from the Field: Outbreak of Multidrug-Resistant Salmonella Infections Linked to Pork--Washington, 2015.

Kawakami VM, Bottichio L, Angelo K, Linton N, Kissler B, Basler C, Lloyd J, Inouye W, Gonzales E, Rietberg K, Melius B, Oltean H, Wise M, Sinatra J, Marsland P, Li Z, Meek R, Kay M, Duchin J, Lindquist S.

MMWR Morb Mortal Wkly Rep. 2016 Apr 15;65(14):379-81. doi: 10.15585/mmwr.mm6514a4.

17.

Public Health-Seattle & King County and Washington State Department of Health Preexposure Prophylaxis Implementation Guidelines, 2015.

Golden MR, Lindquist S, Dombrowski JC.

Sex Transm Dis. 2016 Apr;43(4):264-5. doi: 10.1097/OLQ.0000000000000427. No abstract available.

PMID:
26967306
18.

Prespecified dose-response analysis for A Very Early Rehabilitation Trial (AVERT).

Bernhardt J, Churilov L, Ellery F, Collier J, Chamberlain J, Langhorne P, Lindley RI, Moodie M, Dewey H, Thrift AG, Donnan G; AVERT Collaboration Group.

Neurology. 2016 Jun 7;86(23):2138-45. doi: 10.1212/WNL.0000000000002459. Epub 2016 Feb 17.

19.

Chemical Genomics-Based Antifungal Drug Discovery: Targeting Glycosylphosphatidylinositol (GPI) Precursor Biosynthesis.

Mann PA, McLellan CA, Koseoglu S, Si Q, Kuzmin E, Flattery A, Harris G, Sher X, Murgolo N, Wang H, Devito K, de Pedro N, Genilloud O, Kahn JN, Jiang B, Costanzo M, Boone C, Garlisi CG, Lindquist S, Roemer T.

ACS Infect Dis. 2015 Jan 9;1(1):59-72. doi: 10.1021/id5000212. Epub 2014 Dec 12.

20.

AVERT2 (a very early rehabilitation trial, a very effective reproductive trigger): retrospective observational analysis of the number of babies born to trial staff.

Bernhardt J, Lindley RI, Lalor E, Ellery F, Chamberlain J, Van Holsteyn J, Collier JM, Dewey HM, Parsons B, Moodie M, Lennon S, Donnan GA, Thrift AG, Churilov L, Langhorne P; AVERT Collaboration Group.

BMJ. 2015 Dec 11;351:h6432. doi: 10.1136/bmj.h6432.

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