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Eosinophil Cytolysis on Immunoglobulin-G Is Associated with Microtubule Formation and Suppression of Rho-Associated Protein Kinase Signaling.

Esnault S, Leet JP, Johansson MW, Barretto KT, Fichtinger PS, Fogerty FJ, Bernau K, Mathur SK, Mosher DF, Sandbo N, Jarjour NN.

Clin Exp Allergy. 2019 Nov 21. doi: 10.1111/cea.13538. [Epub ahead of print]


A disintegrin-like and metalloproteinase domain with thrombospondin type 1 motif 9 (ADAMTS9) regulates fibronectin fibrillogenesis and turnover.

Wang LW, Nandadasa S, Annis DS, Dubail J, Mosher DF, Willard BB, Apte SS.

J Biol Chem. 2019 Jun 21;294(25):9924-9936. doi: 10.1074/jbc.RA118.006479. Epub 2019 May 13.


Pentraxin 3 regulates synaptic function by inducing AMPA receptor clustering via ECM remodeling and β1-integrin.

Fossati G, Pozzi D, Canzi A, Mirabella F, Valentino S, Morini R, Ghirardini E, Filipello F, Moretti M, Gotti C, Annis DS, Mosher DF, Garlanda C, Bottazzi B, Taraboletti G, Mantovani A, Matteoli M, Menna E.

EMBO J. 2019 Jan 3;38(1). pii: e99529. doi: 10.15252/embj.201899529. Epub 2018 Nov 5.


The calcium-binding type III repeats domain of thrombospondin-2 binds to fibroblast growth factor 2 (FGF2).

Rusnati M, Borsotti P, Moroni E, Foglieni C, Chiodelli P, Carminati L, Pinessi D, Annis DS, Paiardi G, Bugatti A, Gori A, Longhi R, Belotti D, Mosher DF, Colombo G, Taraboletti G.

Angiogenesis. 2019 Feb;22(1):133-144. doi: 10.1007/s10456-018-9644-3. Epub 2018 Aug 30.


Control of cytokine-driven eosinophil migratory behavior by TGF-beta-induced protein (TGFBI) and periostin.

Barretto KT, Swanson CM, Nguyen CL, Annis DS, Esnault SJ, Mosher DF, Johansson MW.

PLoS One. 2018 Jul 26;13(7):e0201320. doi: 10.1371/journal.pone.0201320. eCollection 2018.


Roles of fibronectin isoforms in neonatal vascular development and matrix integrity.

Kumra H, Sabatier L, Hassan A, Sakai T, Mosher DF, Brinckmann J, Reinhardt DP.

PLoS Biol. 2018 Jul 23;16(7):e2004812. doi: 10.1371/journal.pbio.2004812. eCollection 2018 Jul.


Myeloid-derived growth factor is a resident endoplasmic reticulum protein.

Bortnov V, Annis DS, Fogerty FJ, Barretto KT, Turton KB, Mosher DF.

J Biol Chem. 2018 Aug 24;293(34):13166-13175. doi: 10.1074/jbc.AC118.002052. Epub 2018 Jun 28.


Proteomic and Phosphoproteomic Changes Induced by Prolonged Activation of Human Eosinophils with IL-3.

Esnault S, Hebert AS, Jarjour NN, Coon JJ, Mosher DF.

J Proteome Res. 2018 Jun 1;17(6):2102-2111. doi: 10.1021/acs.jproteome.8b00057. Epub 2018 May 4.


A Selective Extracellular Matrix Proteomics Approach Identifies Fibronectin Proteolysis by A Disintegrin-like and Metalloprotease Domain with Thrombospondin Type 1 Motifs (ADAMTS16) and Its Impact on Spheroid Morphogenesis.

Schnellmann R, Sack R, Hess D, Annis DS, Mosher DF, Apte SS, Chiquet-Ehrismann R.

Mol Cell Proteomics. 2018 Jul;17(7):1410-1425. doi: 10.1074/mcp.RA118.000676. Epub 2018 Apr 18.


Expression of novel "LOCGEF" isoforms of ARHGEF18 in eosinophils.

Turton KB, Wilkerson EM, Hebert AS, Fogerty FJ, Schira HM, Botros FE, Coon JJ, Mosher DF.

J Leukoc Biol. 2018 Jul;104(1):135-145. doi: 10.1002/JLB.2MA1017-418RR. Epub 2018 Mar 30.


Microtiter assays for quantitation of assembly of plasma and cellular fibronectin.

Tomasini-Johansson BR, Mosher DF.

Methods Cell Biol. 2018;143:157-170. doi: 10.1016/bs.mcb.2017.10.001. Epub 2017 Nov 15.


Adaptation in a Fibronectin Binding Autolysin of Staphylococcus saprophyticus.

Mortimer TD, Annis DS, O'Neill MB, Bohr LL, Smith TM, Poinar HN, Mosher DF, Pepperell CS.

mSphere. 2017 Nov 29;2(6). pii: e00511-17. doi: 10.1128/mSphere.00511-17. eCollection 2017 Nov-Dec.


Proteomics of Eosinophil Activation.

Mosher DF, Wilkerson EM, Turton KB, Hebert AS, Coon JJ.

Front Med (Lausanne). 2017 Sep 29;4:159. doi: 10.3389/fmed.2017.00159. eCollection 2017. Review.


Mepolizumab Attenuates Airway Eosinophil Numbers, but Not Their Functional Phenotype, in Asthma.

Kelly EA, Esnault S, Liu LY, Evans MD, Johansson MW, Mathur S, Mosher DF, Denlinger LC, Jarjour NN.

Am J Respir Crit Care Med. 2017 Dec 1;196(11):1385-1395. doi: 10.1164/rccm.201611-2234OC.


IL-5-stimulated eosinophils adherent to periostin undergo stereotypic morphological changes and ADAM8-dependent migration.

Johansson MW, Khanna M, Bortnov V, Annis DS, Nguyen CL, Mosher DF.

Clin Exp Allergy. 2017 Oct;47(10):1263-1274. doi: 10.1111/cea.12934. Epub 2017 May 5.


IL-3 up-regulates and activates human eosinophil CD32 and αMβ2 integrin causing degranulation.

Esnault S, Johansson MW, Kelly EA, Koenderman L, Mosher DF, Jarjour NN.

Clin Exp Allergy. 2017 Apr;47(4):488-498. doi: 10.1111/cea.12876. Epub 2017 Jan 23.


Merging Absolute and Relative Quantitative PCR Data to Quantify STAT3 Splice Variant Transcripts.

Turton KB, Esnault S, Delain LP, Mosher DF.

J Vis Exp. 2016 Oct 9;(116). doi: 10.3791/54473.


Fibroblasts and Mesenchymal Stromal/Stem Cells Are Phenotypically Indistinguishable.

Denu RA, Nemcek S, Bloom DD, Goodrich AD, Kim J, Mosher DF, Hematti P.

Acta Haematol. 2016;136(2):85-97. doi: 10.1159/000445096. Epub 2016 May 18.


Dynamic structure of plasma fibronectin.

Maurer LM, Ma W, Mosher DF.

Crit Rev Biochem Mol Biol. 2015 Jul-Aug;51(4):213-27. doi: 10.1080/10409238.2016.1184224. Epub 2016 May 17. Review.


The Peripheral Blood Eosinophil Proteome.

Wilkerson EM, Johansson MW, Hebert AS, Westphall MS, Mathur SK, Jarjour NN, Schwantes EA, Mosher DF, Coon JJ.

J Proteome Res. 2016 May 6;15(5):1524-33. doi: 10.1021/acs.jproteome.6b00006. Epub 2016 Apr 1.

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