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Host sirtuin 1 regulates mycobacterial immunopathogenesis and represents a therapeutic target against tuberculosis.

Cheng CY, Gutierrez NM, Marzuki MB, Lu X, Foreman TW, Paleja B, Lee B, Balachander A, Chen J, Tsenova L, Kurepina N, Teng KWW, West K, Mehra S, Zolezzi F, Poidinger M, Kreiswirth B, Kaushal D, Kornfeld H, Newell EW, Singhal A.

Sci Immunol. 2017 Mar;2(9). pii: eaaj1789. doi: 10.1126/sciimmunol.aaj1789. Epub 2017 Mar 24.


Compound 19e, a Novel Glucokinase Activator, Protects against Cytokine-Induced Beta-Cell Apoptosis in INS-1 Cells.

Oh YS, Seo E, Park K, Jun HS.

Front Pharmacol. 2017 Mar 29;8:169. doi: 10.3389/fphar.2017.00169. eCollection 2017.


NF-κB1, c-Rel, and ELK1 inhibit miR-134 expression leading to TAB1 upregulation in paclitaxel-resistant human ovarian cancer.

Shuang T, Wang M, Zhou Y, Shi C, Wang D.

Oncotarget. 2017 Apr 11;8(15):24853-24868. doi: 10.18632/oncotarget.15267.


Concomitant elevations of MMP-9, NGAL, proMMP-9/NGAL and neutrophil elastase in serum of smokers with chronic obstructive pulmonary disease.

Bchir S, Nasr HB, Bouchet S, Benzarti M, Garrouch A, Tabka Z, Susin S, Chahed K, Bauvois B.

J Cell Mol Med. 2017 Jul;21(7):1280-1291. doi: 10.1111/jcmm.13057. Epub 2016 Dec 22.


Impacts of cigarette smoking on immune responsiveness: Up and down or upside down?

Qiu F, Liang CL, Liu H, Zeng YQ, Hou S, Huang S, Lai X, Dai Z.

Oncotarget. 2017 Jan 3;8(1):268-284. doi: 10.18632/oncotarget.13613.


Redox control of senescence and age-related disease.

Chandrasekaran A, Idelchik MDPS, Melendez JA.

Redox Biol. 2017 Apr;11:91-102. doi: 10.1016/j.redox.2016.11.005. Epub 2016 Nov 16. Review.


Inactivation of Sirt1 in mouse livers protects against endotoxemic liver injury by acetylating and activating NF-κB.

Cui X, Chen Q, Dong Z, Xu L, Lu T, Li D, Zhang J, Zhang M, Xia Q.

Cell Death Dis. 2016 Oct 6;7(10):e2403. doi: 10.1038/cddis.2016.270.


A Novel Role for SIRT3 in Regulating Mediators Involved in the Terminal Pathways of Human Labor and Delivery.

Lim R, Barker G, Menon R, Lappas M.

Biol Reprod. 2016 Nov;95(5):95. Epub 2016 Sep 14.


MicroRNA-34a Negatively Regulates Efferocytosis by Tissue Macrophages in Part via SIRT1.

McCubbrey AL, Nelson JD, Stolberg VR, Blakely PK, McCloskey L, Janssen WJ, Freeman CM, Curtis JL.

J Immunol. 2016 Feb 1;196(3):1366-75. doi: 10.4049/jimmunol.1401838. Epub 2015 Dec 30.


Deacetylation-mediated interaction of SIRT1-HMGB1 improves survival in a mouse model of endotoxemia.

Hwang JS, Choi HS, Ham SA, Yoo T, Lee WJ, Paek KS, Seo HG.

Sci Rep. 2015 Nov 2;5:15971. doi: 10.1038/srep15971.


Circadian molecular clock in lung pathophysiology.

Sundar IK, Yao H, Sellix MT, Rahman I.

Am J Physiol Lung Cell Mol Physiol. 2015 Nov 15;309(10):L1056-75. doi: 10.1152/ajplung.00152.2015. Epub 2015 Sep 11. Review.


BET Inhibition Upregulates SIRT1 and Alleviates Inflammatory Responses.

Kokkola T, Suuronen T, Pesonen M, Filippakopoulos P, Salminen A, Jarho EM, Lahtela-Kakkonen M.

Chembiochem. 2015 Sep 21;16(14):1997-2001. doi: 10.1002/cbic.201500272. Epub 2015 Aug 13.


SIRT1 protects rat lung tissue against severe burn-induced remote ALI by attenuating the apoptosis of PMVECs via p38 MAPK signaling.

Bai X, Fan L, He T, Jia W, Yang L, Zhang J, Liu Y, Shi J, Su L, Hu D.

Sci Rep. 2015 May 20;5:10277. doi: 10.1038/srep10277.


SIRT1 mediates a primed response to immune challenge after traumatic lung injury.

Smith LM, Wells JD, Vachharajani VT, Yoza BK, McCall CE, Hoth JJ.

J Trauma Acute Care Surg. 2015 May;78(5):1034-8. doi: 10.1097/TA.0000000000000598.


Disruption of Sirtuin 1-Mediated Control of Circadian Molecular Clock and Inflammation in Chronic Obstructive Pulmonary Disease.

Yao H, Sundar IK, Huang Y, Gerloff J, Sellix MT, Sime PJ, Rahman I.

Am J Respir Cell Mol Biol. 2015 Dec;53(6):782-92. doi: 10.1165/rcmb.2014-0474OC.


Intercellular interplay between Sirt1 signalling and cell metabolism in immune cell biology.

Chen X, Lu Y, Zhang Z, Wang J, Yang H, Liu G.

Immunology. 2015 Aug;145(4):455-67. doi: 10.1111/imm.12473. Epub 2015 Jun 3. Review.


Chitinase 3-like-1 regulates both visceral fat accumulation and asthma-like Th2 inflammation.

Ahangari F, Sood A, Ma B, Takyar S, Schuyler M, Qualls C, Dela Cruz CS, Chupp GL, Lee CG, Elias JA.

Am J Respir Crit Care Med. 2015 Apr 1;191(7):746-57. doi: 10.1164/rccm.201405-0796OC.


Immunomodulatory effects of bee venom in human synovial fibroblast cell line.

Mohammadi E, Vatanpour H, H Shirazi F.

Iran J Pharm Res. 2015 Winter;14(1):313-20.

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