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Items: 1 to 20 of 94

1.

The importance of leukotrienes in mast cell-mediated Toxoplasma gondii cytotoxicity.

Henderson WR Jr, Chi EY.

J Infect Dis. 1998 May;177(5):1437-43.

PMID:
9593043
3.

Thiopyrano[2,3,4-cd]indoles as 5-lipoxygenase inhibitors: synthesis, biological profile, and resolution of 2-[2-[1-(4-chlorobenzyl)-4-methyl-6-[(5-phenylpyridin-2-yl)methoxy]-4,5 -dihydro-1H-thiopyrano[2,3,4-cd]indol-2-yl]ethoxy]butanoic acid.

Hutchinson JH, Riendeau D, Brideau C, Chan C, Falgueyret JP, Guay J, Jones TR, L├ępine C, Macdonald D, McFarlane CS, et al.

J Med Chem. 1994 Apr 15;37(8):1153-64.

PMID:
8164257
4.

Calcium-dependent eicosanoid metabolism by concanavalin A-stimulated human monocytes in vitro. Synergism with phorbol ester indicates separate regulation of leukotriene B4 synthesis and release.

Hoffman T, Brando C, Lizzio EF, Lee YL, Hansen M, Tripathi AK, Taplits M, Puri J, Bonvini E, Abrahamsen TG, et al.

J Immunol. 1991 Jan 15;146(2):692-700.

PMID:
1846160
5.

Tenidap inhibits 5-lipoxygenase product formation in vitro, but this activity is not observed in three animal models.

Carty TJ, Sweeney FJ, Griffiths RJ, Eskra JD, Ernest MJ, Pillar JS, Cheng JD, Loose LD, Joseph PA, Pazoles PP, Moore PF, Nagahisa A, Murase S, Kadin SB.

Inflamm Res. 1997 May;46(5):168-79.

PMID:
9197987
6.

SCF-induced airway hyperreactivity is dependent on leukotriene production.

Oliveira SH, Hogaboam CM, Berlin A, Lukacs NW.

Am J Physiol Lung Cell Mol Physiol. 2001 Jun;280(6):L1242-9.

7.

Leukotrienes and alpha-naphthylisothiocyanate-induced liver injury.

Bailie MB, Dahm LJ, Peters-Golden M, Harris RR, Carter GW, Roth RA.

Toxicology. 1995 Jun 26;100(1-3):139-49.

PMID:
7624871
8.

5-Lipoxygenase: enzyme expression and regulation of activity.

Steinhilber D.

Pharm Acta Helv. 1994 Jul;69(1):3-14. Review.

PMID:
7938075
9.

Effects of tepoxalin, a dual inhibitor of cyclooxygenase/5-lipoxygenase, on events associated with NSAID-induced gastrointestinal inflammation.

Kirchner T, Aparicio B, Argentieri DC, Lau CY, Ritchie DM.

Prostaglandins Leukot Essent Fatty Acids. 1997 Jun;56(6):417-23.

PMID:
9223651
10.

The regulation of 5-lipoxygenase activity in rat basophilic leukemia cells.

Wong A, Hwang SM, Cook MN.

Adv Prostaglandin Thromboxane Leukot Res. 1990;20:28-34. No abstract available.

PMID:
2169181
11.

Activation of the human neutrophil 5-lipoxygenase by leukotriene B4.

McDonald PP, McColl SR, Naccache PH, Borgeat P.

Br J Pharmacol. 1992 Sep;107(1):226-32.

12.

[Suppression of 5-lipoxygenase activity by anionic cholesterol derivatives].

Aleksandov DA, Sud'ina GF.

Biomed Khim. 2006 Sep-Oct;52(5):511-7. Russian.

PMID:
17180926
13.

Characterization and modulation of canine mast cell derived eicosanoids.

Lin TY, London CA.

Vet Immunol Immunopathol. 2010 May 15;135(1-2):118-27. doi: 10.1016/j.vetimm.2009.11.010. Epub 2009 Nov 24.

14.
15.

The 5-lipoxygenase inhibitor RF-22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo.

Schaible AM, Filosa R, Krauth V, Temml V, Pace S, Garscha U, Liening S, Weinigel C, Rummler S, Schieferdecker S, Nett M, Peduto A, Collarile S, Scuotto M, Roviezzo F, Spaziano G, de Rosa M, Stuppner H, Schuster D, D'Agostino B, Werz O.

Biochem Pharmacol. 2016 Jul 15;112:60-71. doi: 10.1016/j.bcp.2016.04.019. Epub 2016 May 5.

PMID:
27157409
16.
17.

Protein kinase A inhibits leukotriene synthesis by phosphorylation of 5-lipoxygenase on serine 523.

Luo M, Jones SM, Phare SM, Coffey MJ, Peters-Golden M, Brock TG.

J Biol Chem. 2004 Oct 1;279(40):41512-20. Epub 2004 Jul 26.

18.

Capacity for repeatable leukotriene generation after transient stimulation of mast cells and macrophages.

Brock TG, McNish RW, Peters-Golden M.

Biochem J. 1998 Feb 1;329 ( Pt 3):519-25.

19.

Resident mast cells are the main initiators of anaphylactic leukotriene production in the liver.

Hagmann W, Hacker HJ, Buchholz U.

Hepatology. 1992 Dec;16(6):1477-84.

PMID:
1446900
20.

Inhibition of equine mononuclear cell proliferation and leukotriene B4 synthesis by a specific 5-lipoxygenase inhibitor, A-63162.

Olsen SC, Atluru D, Atluru S, McVey DS, Erickson HH.

Am J Vet Res. 1992 Jun;53(6):1015-8.

PMID:
1320811

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