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Items: 1 to 20 of 94

1.

Low pH activates the vacuolating toxin of Helicobacter pylori, which becomes acid and pepsin resistant.

de Bernard M, Papini E, de Filippis V, Gottardi E, Telford J, Manetti R, Fontana A, Rappuoli R, Montecucco C.

J Biol Chem. 1995 Oct 13;270(41):23937-40.

2.
3.

Cell vacuolization induced by Helicobacter pylori VacA toxin: cell line sensitivity and quantitative estimation.

de Bernard M, Moschioni M, Papini E, Telford J, Rappuoli R, Montecucco C.

Toxicol Lett. 1998 Oct 15;99(2):109-15.

PMID:
9817082
4.

Random mutagenesis of Helicobacter pylori vacA to identify amino acids essential for vacuolating cytotoxic activity.

McClain MS, Czajkowsky DM, Torres VJ, Szabo G, Shao Z, Cover TL.

Infect Immun. 2006 Nov;74(11):6188-95. Epub 2006 Sep 5.

5.

Vacuolating cytotoxin A (VacA) - A multi-talented pore-forming toxin from Helicobacter pylori.

Junaid M, Linn AK, Javadi MB, Al-Gubare S, Ali N, Katzenmeier G.

Toxicon. 2016 Aug;118:27-35. doi: 10.1016/j.toxicon.2016.04.037. Epub 2016 Apr 20. Review.

PMID:
27105670
6.
7.

Enterotoxic effect of the vacuolating toxin produced by Helicobacter pylori in Caco-2 cells.

Guarino A, Bisceglia M, Canani RB, Boccia MC, Mallardo G, Bruzzese E, Massari P, Rappuoli R, Telford J.

J Infect Dis. 1998 Nov;178(5):1373-8.

PMID:
9780258
8.

Acid activation of Helicobacter pylori vacuolating cytotoxin (VacA) results in toxin internalization by eukaryotic cells.

McClain MS, Schraw W, Ricci V, Boquet P, Cover TL.

Mol Microbiol. 2000 Jul;37(2):433-42.

9.

Induction of gastric epithelial cell apoptosis by Helicobacter pylori vacuolating cytotoxin.

Cover TL, Krishna US, Israel DA, Peek RM Jr.

Cancer Res. 2003 Mar 1;63(5):951-7.

10.

Helicobacter pylori vacuolating toxin forms anion-selective channels in planar lipid bilayers: possible implications for the mechanism of cellular vacuolation.

Tombola F, Carlesso C, Szabò I, de Bernard M, Reyrat JM, Telford JL, Rappuoli R, Montecucco C, Papini E, Zoratti M.

Biophys J. 1999 Mar;76(3):1401-9.

11.
12.

Helicobacter pylori VacA, a distinct toxin exerts diverse functionalities in numerous cells: An overview.

Chauhan N, Tay ACY, Marshall BJ, Jain U.

Helicobacter. 2019 Feb;24(1):e12544. doi: 10.1111/hel.12544. Epub 2018 Oct 16. Review.

PMID:
30324717
13.

Lipid interaction of the 37-kDa and 58-kDa fragments of the Helicobacter pylori cytotoxin.

Moll G, Papini E, Colonna R, Burroni D, Telford J, Rappuoli R, Montecucco C.

Eur J Biochem. 1995 Dec 15;234(3):947-52.

14.

Vacuoles induced by Helicobacter pylori toxin contain both late endosomal and lysosomal markers.

Molinari M, Galli C, Norais N, Telford JL, Rappuoli R, Luzio JP, Montecucco C.

J Biol Chem. 1997 Oct 3;272(40):25339-44.

15.

Helicobacter pylori cytotoxin: importance of native conformation for induction of neutralizing antibodies.

Manetti R, Massari P, Burroni D, de Bernard M, Marchini A, Olivieri R, Papini E, Montecucco C, Rappuoli R, Telford JL.

Infect Immun. 1995 Nov;63(11):4476-80.

16.
17.

Towards deciphering the Helicobacter pylori cytotoxin.

Reyrat JM, Pelicic V, Papini E, Montecucco C, Rappuoli R, Telford JL.

Mol Microbiol. 1999 Oct;34(2):197-204. Review.

18.

Identification of the Helicobacter pylori VacA toxin domain active in the cell cytosol.

de Bernard M, Burroni D, Papini E, Rappuoli R, Telford J, Montecucco C.

Infect Immun. 1998 Dec;66(12):6014-6.

19.

A dominant negative mutant of Helicobacter pylori vacuolating toxin (VacA) inhibits VacA-induced cell vacuolation.

Vinion-Dubiel AD, McClain MS, Czajkowsky DM, Iwamoto H, Ye D, Cao P, Schraw W, Szabo G, Blanke SR, Shao Z, Cover TL.

J Biol Chem. 1999 Dec 31;274(53):37736-42.

20.

An intracellular target for Helicobacter pylori vacuolating toxin.

Cover TL.

Trends Microbiol. 1998 Apr;6(4):127-8; discussion 128-9. Review. No abstract available.

PMID:
9587185

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