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Items: 1 to 20 of 62

1.

NIRF/UHRF2 occupies a central position in the cell cycle network and allows coupling with the epigenetic landscape.

Mori T, Ikeda DD, Yamaguchi Y, Unoki M; NIRF Project.

FEBS Lett. 2012 Jun 4;586(11):1570-83. doi: 10.1016/j.febslet.2012.04.038. Epub 2012 Apr 30. Review.

2.

NIRF constitutes a nodal point in the cell cycle network and is a candidate tumor suppressor.

Mori T, Ikeda DD, Fukushima T, Takenoshita S, Kochi H.

Cell Cycle. 2011 Oct 1;10(19):3284-99. doi: 10.4161/cc.10.19.17176. Epub 2011 Oct 1.

3.

UHRF2, another E3 ubiquitin ligase for p53.

Bai L, Wang X, Jin F, Yang Y, Qian G, Duan C.

Biochem Biophys Res Commun. 2012 Sep 7;425(4):908-11. doi: 10.1016/j.bbrc.2012.08.009. Epub 2012 Aug 9. Retraction in: Biochem Biophys Res Commun. 2013 Nov 1;440(4):803.

PMID:
22902639
4.

S phase-dependent interaction with DNMT1 dictates the role of UHRF1 but not UHRF2 in DNA methylation maintenance.

Zhang J, Gao Q, Li P, Liu X, Jia Y, Wu W, Li J, Dong S, Koseki H, Wong J.

Cell Res. 2011 Dec;21(12):1723-39. doi: 10.1038/cr.2011.176. Epub 2011 Nov 8.

5.

Cooperative DNA and histone binding by Uhrf2 links the two major repressive epigenetic pathways.

Pichler G, Wolf P, Schmidt CS, Meilinger D, Schneider K, Frauer C, Fellinger K, Rottach A, Leonhardt H.

J Cell Biochem. 2011 Sep;112(9):2585-93. doi: 10.1002/jcb.23185.

6.

Dynamical analysis of cellular ageing by modeling of gene regulatory network based attractor landscape.

Chong KH, Zhang X, Zheng J.

PLoS One. 2018 Jun 1;13(6):e0197838. doi: 10.1371/journal.pone.0197838. eCollection 2018.

7.

NIRF induces G1 arrest and associates with Cdk2.

Li Y, Mori T, Hata H, Homma Y, Kochi H.

Biochem Biophys Res Commun. 2004 Jun 25;319(2):464-8.

PMID:
15178429
8.

Uhrf2 is important for DNA damage response in vascular smooth muscle cells.

Luo T, Cui S, Bian C, Yu X.

Biochem Biophys Res Commun. 2013 Nov 8;441(1):65-70. doi: 10.1016/j.bbrc.2013.10.018. Epub 2013 Oct 14.

9.

NIRF, a novel ubiquitin ligase, interacts with hepatitis B virus core protein and promotes its degradation.

Qian G, Jin F, Chang L, Yang Y, Peng H, Duan C.

Biotechnol Lett. 2012 Jan;34(1):29-36. doi: 10.1007/s10529-011-0751-0. Epub 2011 Nov 10.

PMID:
22072112
10.

UHRF2 regulates local 5-methylcytosine and suppresses spontaneous seizures.

Liu Y, Zhang B, Meng X, Korn MJ, Parent JM, Lu LY, Yu X.

Epigenetics. 2017 Jul 3;12(7):551-560. doi: 10.1080/15592294.2017.1314423. Epub 2017 Apr 12.

11.

NIRF, a Novel Ubiquitin Ligase, Inhibits Hepatitis B Virus Replication Through Effect on HBV Core Protein and H3 Histones.

Qian G, Hu B, Zhou D, Xuan Y, Bai L, Duan C.

DNA Cell Biol. 2015 May;34(5):327-32. doi: 10.1089/dna.2014.2714. Epub 2015 Feb 9.

PMID:
25664994
12.

UHRF2, a ubiquitin E3 ligase, acts as a small ubiquitin-like modifier E3 ligase for zinc finger protein 131.

Oh Y, Chung KC.

J Biol Chem. 2013 Mar 29;288(13):9102-11. doi: 10.1074/jbc.M112.438234. Epub 2013 Feb 12.

13.

The UHRF family: oncogenes that are drugable targets for cancer therapy in the near future?

Bronner C, Achour M, Arima Y, Chataigneau T, Saya H, Schini-Kerth VB.

Pharmacol Ther. 2007 Sep;115(3):419-34. Epub 2007 Jun 22. Review.

PMID:
17658611
14.

Drug discovery targeting epigenetic codes: the great potential of UHRF1, which links DNA methylation and histone modifications, as a drug target in cancers and toxoplasmosis.

Unoki M, Brunet J, Mousli M.

Biochem Pharmacol. 2009 Nov 15;78(10):1279-88. doi: 10.1016/j.bcp.2009.05.035. Epub 2009 Jun 6. Review.

PMID:
19501055
15.

SCF(Fbx4/alphaB-crystallin) E3 ligase: when one is not enough.

Barbash O, Diehl JA.

Cell Cycle. 2008 Oct;7(19):2983-6. Epub 2008 Oct 12. Review.

PMID:
18818515
16.

The epigenetic landscape in the course of time: Conrad Hal Waddington's methodological impact on the life sciences.

Baedke J.

Stud Hist Philos Biol Biomed Sci. 2013 Dec;44(4 Pt B):756-73. doi: 10.1016/j.shpsc.2013.06.001. Epub 2013 Aug 7.

PMID:
23932231
17.

Ubiquitin ligases and cell cycle control.

Teixeira LK, Reed SI.

Annu Rev Biochem. 2013;82:387-414. doi: 10.1146/annurev-biochem-060410-105307. Epub 2013 Mar 13. Review.

PMID:
23495935
18.

The nuclear protein UHRF2 is a direct target of the transcription factor E2F1 in the induction of apoptosis.

Lu H, Hallstrom TC.

J Biol Chem. 2013 Aug 16;288(33):23833-43. doi: 10.1074/jbc.M112.447276. Epub 2013 Jul 5.

19.

Cell cycle, proteolysis and cancer.

Yamasaki L, Pagano M.

Curr Opin Cell Biol. 2004 Dec;16(6):623-8. Review.

PMID:
15530772
20.

A deterministic map of Waddington's epigenetic landscape for cell fate specification.

Bhattacharya S, Zhang Q, Andersen ME.

BMC Syst Biol. 2011 May 27;5:85. doi: 10.1186/1752-0509-5-85.

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