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Influenza A virus neuraminidase protein enhances cell survival through interaction with carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) protein.

Gaur P, Ranjan P, Sharma S, Patel JR, Bowzard JB, Rahman SK, Kumari R, Gangappa S, Katz JM, Cox NJ, Lal RB, Sambhara S, Lal SK.

J Biol Chem. 2012 Apr 27;287(18):15109-17. doi: 10.1074/jbc.M111.328070. Epub 2012 Mar 6.


Modulation of an ectodomain motif in the influenza A virus neuraminidase alters tetherin sensitivity and results in virus attenuation in vivo.

Leyva-Grado VH, Hai R, Fernandes F, Belicha-Villanueva A, Carter C, Yondola MA.

J Mol Biol. 2014 Mar 20;426(6):1308-21. doi: 10.1016/j.jmb.2013.12.023. Epub 2013 Dec 29.


Transport of influenza virus neuraminidase (NA) to host cell surface is regulated by ARHGAP21 and Cdc42 proteins.

Wang S, Li H, Chen Y, Wei H, Gao GF, Liu H, Huang S, Chen JL.

J Biol Chem. 2012 Mar 23;287(13):9804-16. doi: 10.1074/jbc.M111.312959. Epub 2012 Feb 8.


Expression of Carcinoembryonic Cell Adhesion Molecule 6 and Alveolar Epithelial Cell Markers in Lungs of Human Infants with Chronic Lung Disease.

Gonzales LW, Gonzalez R, Barrette AM, Wang P, Dobbs L, Ballard PL.

J Histochem Cytochem. 2015 Dec;63(12):908-21. doi: 10.1369/0022155415603768. Epub 2015 Sep 15.


CEACAM6 promotes gastric cancer invasion and metastasis by inducing epithelial-mesenchymal transition via PI3K/AKT signaling pathway.

Zang M, Zhang B, Zhang Y, Li J, Su L, Zhu Z, Gu Q, Liu B, Yan M.

PLoS One. 2014 Nov 14;9(11):e112908. doi: 10.1371/journal.pone.0112908. eCollection 2014.


MicroRNA-29a suppresses the growth, migration, and invasion of lung adenocarcinoma cells by targeting carcinoembryonic antigen-related cell adhesion molecule 6.

Han HS, Son SM, Yun J, Jo YN, Lee OJ.

FEBS Lett. 2014 Oct 16;588(20):3744-50. doi: 10.1016/j.febslet.2014.08.023. Epub 2014 Aug 27.


Influenza viral neuraminidase primes bacterial coinfection through TGF-β-mediated expression of host cell receptors.

Li N, Ren A, Wang X, Fan X, Zhao Y, Gao GF, Cleary P, Wang B.

Proc Natl Acad Sci U S A. 2015 Jan 6;112(1):238-43. doi: 10.1073/pnas.1414422112. Epub 2014 Dec 22.


Activation of Akt/GSK3β and Akt/Bcl-2 signaling pathways in nickel-transformed BEAS-2B cells.

Pan JJ, Chang QS, Wang X, Son YO, Liu J, Zhang Z, Bi YY, Shi X.

Int J Oncol. 2011 Nov;39(5):1285-94. doi: 10.3892/ijo.2011.1157. Epub 2011 Aug 11.


Nerve growth factor modulates human rhinovirus infection in airway epithelial cells by controlling ICAM-1 expression.

Othumpangat S, Regier M, Piedimonte G.

Am J Physiol Lung Cell Mol Physiol. 2012 May 15;302(10):L1057-66. doi: 10.1152/ajplung.00365.2011. Epub 2012 Mar 16.


CEACAM6 promotes tumor angiogenesis and vasculogenic mimicry in gastric cancer via FAK signaling.

Zang M, Zhang Y, Zhang B, Hu L, Li J, Fan Z, Wang H, Su L, Zhu Z, Li C, Yan C, Gu Q, Liu B, Yan M.

Biochim Biophys Acta. 2015 May;1852(5):1020-8. doi: 10.1016/j.bbadis.2015.02.005. Epub 2015 Feb 19.


A small molecule multi-kinase inhibitor reduces influenza A virus replication by restricting viral RNA synthesis.

Martinez-Gil L, Alamares-Sapuay JG, Ramana Reddy MV, Goff PH, Premkumar Reddy E, Palese P.

Antiviral Res. 2013 Oct;100(1):29-37. doi: 10.1016/j.antiviral.2013.07.010. Epub 2013 Jul 24.


Neuraminidase of Influenza A Virus Binds Lysosome-Associated Membrane Proteins Directly and Induces Lysosome Rupture.

Ju X, Yan Y, Liu Q, Li N, Sheng M, Zhang L, Li X, Liang Z, Huang F, Liu K, Zhao Y, Zhang Y, Zou Z, Du J, Zhong Y, Zhou H, Yang P, Lu H, Tian M, Li D, Zhang J, Jin N, Jiang C.

J Virol. 2015 Oct;89(20):10347-58. doi: 10.1128/JVI.01411-15. Epub 2015 Aug 5.


Trask phosphorylation defines the reverse mode of a phosphotyrosine signaling switch that underlies cell anchorage state.

Spassov DS, Wong CH, Moasser MM.

Cell Cycle. 2011 Apr 15;10(8):1225-32. Epub 2011 Apr 15.


Suppression of autophagy by CUB domain-containing protein 1 signaling is essential for anchorage-independent survival of lung cancer cells.

Uekita T, Fujii S, Miyazawa Y, Hashiguchi A, Abe H, Sakamoto M, Sakai R.

Cancer Sci. 2013 Jul;104(7):865-70. doi: 10.1111/cas.12154. Epub 2013 Apr 19.


Tamoxifen treatment promotes phosphorylation of the adhesion molecules, p130Cas/BCAR1, FAK and Src, via an adhesion-dependent pathway.

Cowell LN, Graham JD, Bouton AH, Clarke CL, O'Neill GM.

Oncogene. 2006 Dec 7;25(58):7597-607. Epub 2006 Jun 26.


Inactivated Sendai virus induces apoptosis and autophagy via the PI3K/Akt/mTOR/p70S6K pathway in human non-small cell lung cancer cells.

Zhang Q, Zhu H, Xu X, Li L, Tan H, Cai X.

Biochem Biophys Res Commun. 2015 Sep 11;465(1):64-70. doi: 10.1016/j.bbrc.2015.07.130. Epub 2015 Jul 30.


CEACAM6 attenuates adenovirus infection by antagonizing viral trafficking in cancer cells.

Wang Y, Gangeswaran R, Zhao X, Wang P, Tysome J, Bhakta V, Yuan M, Chikkanna-Gowda CP, Jiang G, Gao D, Cao F, Francis J, Yu J, Liu K, Yang H, Zhang Y, Zang W, Chelala C, Dong Z, Lemoine N.

J Clin Invest. 2009 Jun;119(6):1604-15. doi: 10.1172/JCI37905.


Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) promotes EGF receptor signaling of oral squamous cell carcinoma metastasis via the complex N-glycosylation.

Chiang WF, Cheng TM, Chang CC, Pan SH, Changou CA, Chang TH, Lee KH, Wu SY, Chen YF, Chuang KH, Shieh DB, Chen YL, Tu CC, Tsui WL, Wu MH.

Oncogene. 2018 Jan 4;37(1):116-127. doi: 10.1038/onc.2017.303. Epub 2017 Sep 11.


Dextran sulfate-resistant A/Puerto Rico/8/34 influenza virus is associated with the emergence of specific mutations in the neuraminidase glycoprotein.

Yamada H, Nagao C, Haredy AM, Mori Y, Mizuguchi K, Yamanishi K, Okamoto S.

Antiviral Res. 2014 Nov;111:69-77. doi: 10.1016/j.antiviral.2014.09.002. Epub 2014 Sep 16.


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