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Items: 1 to 20 of 111

1.

Interactions between the ROP18 kinase and host cell proteins that aid in the parasitism of Toxoplasma gondii.

Cheng L, Chen Y, Chen L, Shen Y, Shen J, An R, Luo Q, Du J.

Acta Trop. 2012 Jun;122(3):255-60. doi: 10.1016/j.actatropica.2012.02.065. Epub 2012 Feb 16.

PMID:
22365922
2.

[Screening of host cell proteins that interact with Toxoplasma gondii ROP18 via yeast two-hybrid system].

Du J, An R, Cheng L, Chen Y, Shen JL.

Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2013 Feb;31(1):18-22. Chinese.

PMID:
24812831
3.

ATF6beta is a host cellular target of the Toxoplasma gondii virulence factor ROP18.

Yamamoto M, Ma JS, Mueller C, Kamiyama N, Saiga H, Kubo E, Kimura T, Okamoto T, Okuyama M, Kayama H, Nagamune K, Takashima S, Matsuura Y, Soldati-Favre D, Takeda K.

J Exp Med. 2011 Jul 4;208(7):1533-46. doi: 10.1084/jem.20101660. Epub 2011 Jun 13.

4.

Toxoplasma gondii virulence factor ROP18 inhibits the host NF-κB pathway by promoting p65 degradation.

Du J, An R, Chen L, Shen Y, Chen Y, Cheng L, Jiang Z, Zhang A, Yu L, Chu D, Shen Y, Luo Q, Chen H, Wan L, Li M, Xu X, Shen J.

J Biol Chem. 2014 May 2;289(18):12578-92. doi: 10.1074/jbc.M113.544718. Epub 2014 Mar 19.

5.

Inhibition of ATF6β-dependent host adaptive immune response by a Toxoplasma virulence factor ROP18.

Yamamoto M, Takeda K.

Virulence. 2012 Jan-Feb;3(1):77-80. doi: 10.4161/viru.3.1.18340. Epub 2012 Jan 1.

PMID:
22286708
6.

A Toxoplasma gondii pseudokinase inhibits host IRG resistance proteins.

Fleckenstein MC, Reese ML, Könen-Waisman S, Boothroyd JC, Howard JC, Steinfeldt T.

PLoS Biol. 2012;10(7):e1001358. doi: 10.1371/journal.pbio.1001358. Epub 2012 Jul 10.

7.

The Toxoplasma pseudokinase ROP5 forms complexes with ROP18 and ROP17 kinases that synergize to control acute virulence in mice.

Etheridge RD, Alaganan A, Tang K, Lou HJ, Turk BE, Sibley LD.

Cell Host Microbe. 2014 May 14;15(5):537-50. doi: 10.1016/j.chom.2014.04.002.

9.

Association of ROP18 and ROP5 was efficient as a marker of virulence in atypical isolates of Toxoplasma gondii obtained from pigs and goats in Piauí, Brazil.

Rêgo WMF, Costa JGL, Baraviera RCA, Pinto LV, Bessa GL, Lopes REN, Vitor RWA.

Vet Parasitol. 2017 Nov 30;247:19-25. doi: 10.1016/j.vetpar.2017.09.015. Epub 2017 Sep 22.

PMID:
29080759
10.

The arginine-rich N-terminal domain of ROP18 is necessary for vacuole targeting and virulence of Toxoplasma gondii.

Fentress SJ, Steinfeldt T, Howard JC, Sibley LD.

Cell Microbiol. 2012 Dec;14(12):1921-33. doi: 10.1111/cmi.12022. Epub 2012 Sep 20.

11.

A secreted serine-threonine kinase determines virulence in the eukaryotic pathogen Toxoplasma gondii.

Taylor S, Barragan A, Su C, Fux B, Fentress SJ, Tang K, Beatty WL, Hajj HE, Jerome M, Behnke MS, White M, Wootton JC, Sibley LD.

Science. 2006 Dec 15;314(5806):1776-80.

12.

Proteasomal degradation of T. gondii ROP18 requires Derlin2.

Tang Y, Zheng M, An R, Chen L, Gong L, Cai H, Liu K, Yu L, Shen J, Du J.

Acta Trop. 2017 Oct;174:106-113. doi: 10.1016/j.actatropica.2017.06.027. Epub 2017 Jun 29.

PMID:
28669563
13.

Encephalitis is mediated by ROP18 of Toxoplasma gondii, a severe pathogen in AIDS patients.

An R, Tang Y, Chen L, Cai H, Lai DH, Liu K, Wan L, Gong L, Yu L, Luo Q, Shen J, Lun ZR, Ayala FJ, Du J.

Proc Natl Acad Sci U S A. 2018 Jun 5;115(23):E5344-E5352. doi: 10.1073/pnas.1801118115. Epub 2018 May 21.

14.

ROP18 is a key factor responsible for virulence difference between Toxoplasma gondii and Neospora caninum.

Lei T, Wang H, Liu J, Nan H, Liu Q.

PLoS One. 2014 Jun 13;9(6):e99744. doi: 10.1371/journal.pone.0099744. eCollection 2014.

15.

Secretion of Rhoptry and Dense Granule Effector Proteins by Nonreplicating Toxoplasma gondii Uracil Auxotrophs Controls the Development of Antitumor Immunity.

Fox BA, Sanders KL, Rommereim LM, Guevara RB, Bzik DJ.

PLoS Genet. 2016 Jul 22;12(7):e1006189. doi: 10.1371/journal.pgen.1006189. eCollection 2016 Jul.

16.

Phosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondii.

Steinfeldt T, Könen-Waisman S, Tong L, Pawlowski N, Lamkemeyer T, Sibley LD, Hunn JP, Howard JC.

PLoS Biol. 2010 Dec 21;8(12):e1000576. doi: 10.1371/journal.pbio.1000576. Erratum in: PLoS Biol. 2015 Jul;13(7):e1002199.

17.

Structure of the Toxoplasma gondii ROP18 kinase domain reveals a second ligand binding pocket required for acute virulence.

Lim D, Gold DA, Julien L, Rosowski EE, Niedelman W, Yaffe MB, Saeij JP.

J Biol Chem. 2013 Nov 29;288(48):34968-80. doi: 10.1074/jbc.M113.523266. Epub 2013 Oct 15.

18.

The Toxoplasma gondii rhoptry protein ROP18 is an Irga6-specific kinase and regulated by the dense granule protein GRA7.

Hermanns T, Müller UB, Könen-Waisman S, Howard JC, Steinfeldt T.

Cell Microbiol. 2016 Feb;18(2):244-59. doi: 10.1111/cmi.12499. Epub 2015 Oct 30.

19.

Analysis of the virulence determination mechanisms in a local Toxoplasma strain (T.gHB1) isolated from central China.

Zhang W, Li L, Xia N, Zhou Y, Fang R, He L, Hu M, Shen B, Zhao J.

Parasitol Res. 2016 Oct;115(10):3807-15. doi: 10.1007/s00436-016-5141-z. Epub 2016 May 25.

PMID:
27225000
20.

Selection at a single locus leads to widespread expansion of Toxoplasma gondii lineages that are virulent in mice.

Khan A, Taylor S, Ajioka JW, Rosenthal BM, Sibley LD.

PLoS Genet. 2009 Mar;5(3):e1000404. doi: 10.1371/journal.pgen.1000404. Epub 2009 Mar 6.

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