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Items: 1 to 20 of 122


Determining the phagocytic activity of clinical antibody samples.

McAndrew EG, Dugast AS, Licht AF, Eusebio JR, Alter G, Ackerman ME.

J Vis Exp. 2011 Nov 30;(57):e3588. doi: 10.3791/3588.


A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples.

Ackerman ME, Moldt B, Wyatt RT, Dugast AS, McAndrew E, Tsoukas S, Jost S, Berger CT, Sciaranghella G, Liu Q, Irvine DJ, Burton DR, Alter G.

J Immunol Methods. 2011 Mar 7;366(1-2):8-19. doi: 10.1016/j.jim.2010.12.016. Epub 2010 Dec 27. Erratum in: J Immunol Methods. 2012 Feb 28;376(1-2):156.


Simultaneous flow cytometric measurement of antigen attachment to phagocytes and phagocytosis.

Laopajon W, Takheaw N, Kasinrerk W, Pata S.

J Immunoassay Immunochem. 2016;37(5):527-39. doi: 10.1080/15321819.2016.1171780.


Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination.

Mahan AE, Jennewein MF, Suscovich T, Dionne K, Tedesco J, Chung AW, Streeck H, Pau M, Schuitemaker H, Francis D, Fast P, Laufer D, Walker BD, Baden L, Barouch DH, Alter G.

PLoS Pathog. 2016 Mar 16;12(3):e1005456. doi: 10.1371/journal.ppat.1005456. eCollection 2016 Mar. Erratum in: PLoS Pathog. 2016 Jun;12(6):e1005694.


Enhanced phagocytic activity of HIV-specific antibodies correlates with natural production of immunoglobulins with skewed affinity for FcγR2a and FcγR2b.

Ackerman ME, Dugast AS, McAndrew EG, Tsoukas S, Licht AF, Irvine DJ, Alter G.

J Virol. 2013 May;87(10):5468-76. doi: 10.1128/JVI.03403-12. Epub 2013 Mar 6.


Human platelet FcγRIIA and phagocytes in immune-complex clearance.

Huang ZY, Chien P, Indik ZK, Schreiber AD.

Mol Immunol. 2011 Jan;48(4):691-6. doi: 10.1016/j.molimm.2010.11.017. Epub 2010 Dec 17.


IgG2 inhibits HIV-1 internalization by monocytes, and IgG subclass binding is affected by gp120 glycosylation.

Forthal DN, Landucci G, Ding H, Kappes JC, Wang A, Thung I, Phan T.

AIDS. 2011 Nov 13;25(17):2099-104. doi: 10.1097/QAD.0b013e32834b64bd.


Enhancement of antibody-dependent cell-mediated cytotoxicity by endowing IgG with FcαRI (CD89) binding.

Borrok MJ, Luheshi NM, Beyaz N, Davies GC, Legg JW, Wu H, Dall'Acqua WF, Tsui P.

MAbs. 2015;7(4):743-51. doi: 10.1080/19420862.2015.1047570.


Dimeric FcγR Ectodomains as Probes of the Fc Receptor Function of Anti-Influenza Virus IgG.

Wines BD, Vanderven HA, Esparon SE, Kristensen AB, Kent SJ, Hogarth PM.

J Immunol. 2016 Aug 15;197(4):1507-16. doi: 10.4049/jimmunol.1502551. Epub 2016 Jul 6.


Human IgG isotypes and activating Fcγ receptors in the interaction of Salmonella enterica serovar Typhimurium with phagocytic cells.

Goh YS, Grant AJ, Restif O, McKinley TJ, Armour KL, Clark MR, Mastroeni P.

Immunology. 2011 May;133(1):74-83. doi: 10.1111/j.1365-2567.2011.03411.x. Epub 2011 Feb 16.


Bispecific antibody-targeted phagocytosis of HER-2/neu expressing tumor cells by myeloid cells activated in vivo.

Wallace PK, Kaufman PA, Lewis LD, Keler T, Givan AL, Fisher JL, Waugh MG, Wahner AE, Guyre PM, Fanger MW, Ernstoff MS.

J Immunol Methods. 2001 Feb 1;248(1-2):167-82.


CD14(hi)CD16+ monocytes phagocytose antibody-opsonised Plasmodium falciparum infected erythrocytes more efficiently than other monocyte subsets, and require CD16 and complement to do so.

Zhou J, Feng G, Beeson J, Hogarth PM, Rogerson SJ, Yan Y, Jaworowski A.

BMC Med. 2015 Jul 7;13:154. doi: 10.1186/s12916-015-0391-7. Erratum in: BMC Med. 2015;13:290.


Interactions of phagocytes with the Lyme disease spirochete: role of the Fc receptor.

Benach JL, Fleit HB, Habicht GS, Coleman JL, Bosler EM, Lane BP.

J Infect Dis. 1984 Oct;150(4):497-507.


Humanized mAb H22 binds the human high affinity Fc receptor for IgG (FcgammaRI), blocks phagocytosis, and modulates receptor expression.

Wallace PK, Keler T, Coleman K, Fisher J, Vitale L, Graziano RF, Guyre PM, Fanger MW.

J Leukoc Biol. 1997 Oct;62(4):469-79.


Chemical compounds that target thiol-disulfide groups on mononuclear phagocytes inhibit immune mediated phagocytosis of red blood cells.

Rampersad GC, Suck G, Sakac D, Fahim S, Foo A, Denomme GA, Langler RF, Branch DR.

Transfusion. 2005 Mar;45(3):384-93.


Humanised IgG1 antibody variants targeting membrane-bound carcinoembryonic antigen by antibody-dependent cellular cytotoxicity and phagocytosis.

Ashraf SQ, Umana P, Mössner E, Ntouroupi T, Brünker P, Schmidt C, Wilding JL, Mortensen NJ, Bodmer WF.

Br J Cancer. 2009 Nov 17;101(10):1758-68. doi: 10.1038/sj.bjc.6605355.


Role of neutrophil Fc gamma RIIa (CD32) and Fc gamma RIIIb (CD16) polymorphic forms in phagocytosis of human IgG1- and IgG3-opsonized bacteria and erythrocytes.

Bredius RG, Fijen CA, De Haas M, Kuijper EJ, Weening RS, Van de Winkel JG, Out TA.

Immunology. 1994 Dec;83(4):624-30.

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