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Items: 1 to 20 of 96

1.

IgM-mediated autoimmune responses directed against multiple neoepitopes in depression: new pathways that underpin the inflammatory and neuroprogressive pathophysiology.

Maes M, Mihaylova I, Kubera M, Leunis JC, Geffard M.

J Affect Disord. 2011 Dec;135(1-3):414-8. doi: 10.1016/j.jad.2011.08.023. Epub 2011 Sep 17.

PMID:
21930301
2.

IgM-mediated autoimmune responses directed against anchorage epitopes are greater in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) than in major depression.

Maes M, Mihaylova I, Kubera M, Leunis JC, Twisk FN, Geffard M.

Metab Brain Dis. 2012 Dec;27(4):415-23. doi: 10.1007/s11011-012-9316-8. Epub 2012 May 22.

PMID:
22614823
4.

Increased autoimmune responses against auto-epitopes modified by oxidative and nitrosative damage in depression: implications for the pathways to chronic depression and neuroprogression.

Maes M, Kubera M, Mihaylova I, Geffard M, Galecki P, Leunis JC, Berk M.

J Affect Disord. 2013 Jul;149(1-3):23-9. doi: 10.1016/j.jad.2012.06.039. Epub 2012 Aug 13.

PMID:
22898471
6.

In depression, bacterial translocation may drive inflammatory responses, oxidative and nitrosative stress (O&NS), and autoimmune responses directed against O&NS-damaged neoepitopes.

Maes M, Kubera M, Leunis JC, Berk M, Geffard M, Bosmans E.

Acta Psychiatr Scand. 2013 May;127(5):344-54. doi: 10.1111/j.1600-0447.2012.01908.x. Epub 2012 Aug 17.

PMID:
22900942
7.

Natural regulatory IgM-mediated autoimmune responses directed against malondialdehyde regulate oxidative and nitrosative pathways and coupled with IgM responses to nitroso adducts attenuate depressive and physiosomatic symptoms at the end of term pregnancy.

Roomruangwong C, Barbosa DS, de Farias CC, Matsumoto AK, Baltus THL, Morelli NR, Kanchanatawan B, Duleu S, Geffard M, Maes M.

Psychiatry Clin Neurosci. 2018 Feb;72(2):116-130. doi: 10.1111/pcn.12625. Epub 2018 Jan 5.

8.

A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness.

Maes M, Galecki P, Chang YS, Berk M.

Prog Neuropsychopharmacol Biol Psychiatry. 2011 Apr 29;35(3):676-92. doi: 10.1016/j.pnpbp.2010.05.004. Epub 2010 May 12. Review.

PMID:
20471444
9.

An intriguing and hitherto unexplained co-occurrence: Depression and chronic fatigue syndrome are manifestations of shared inflammatory, oxidative and nitrosative (IO&NS) pathways.

Maes M.

Prog Neuropsychopharmacol Biol Psychiatry. 2011 Apr 29;35(3):784-94. doi: 10.1016/j.pnpbp.2010.06.023. Epub 2010 Jul 4. Review.

PMID:
20609377
10.

Increased autoimmune activity against 5-HT: a key component of depression that is associated with inflammation and activation of cell-mediated immunity, and with severity and staging of depression.

Maes M, Ringel K, Kubera M, Berk M, Rybakowski J.

J Affect Disord. 2012 Feb;136(3):386-92. doi: 10.1016/j.jad.2011.11.016. Epub 2011 Dec 12.

PMID:
22166399
12.

Increased IgA and IgM responses against gut commensals in chronic depression: further evidence for increased bacterial translocation or leaky gut.

Maes M, Kubera M, Leunis JC, Berk M.

J Affect Disord. 2012 Dec 1;141(1):55-62. doi: 10.1016/j.jad.2012.02.023. Epub 2012 Mar 11.

PMID:
22410503
14.

IgM-mediated autoimmune responses to oxidative specific epitopes, but not nitrosylated adducts, are significantly decreased in pregnancy: association with bacterial translocation, perinatal and lifetime major depression and the tryptophan catabolite (TRYCAT) pathway.

Roomruangwong C, Kanchanatawan B, Sirivichayakul S, Anderson G, Carvalho AF, Duleu S, Geffard M, Maes M.

Metab Brain Dis. 2017 Oct;32(5):1571-1583. doi: 10.1007/s11011-017-0040-2. Epub 2017 Jun 9.

PMID:
28600633
15.
16.

In myalgic encephalomyelitis/chronic fatigue syndrome, increased autoimmune activity against 5-HT is associated with immuno-inflammatory pathways and bacterial translocation.

Maes M, Ringel K, Kubera M, Anderson G, Morris G, Galecki P, Geffard M.

J Affect Disord. 2013 Sep 5;150(2):223-30. doi: 10.1016/j.jad.2013.03.029. Epub 2013 May 10.

PMID:
23664637
18.

Activation of cell-mediated immunity in depression: association with inflammation, melancholia, clinical staging and the fatigue and somatic symptom cluster of depression.

Maes M, Mihaylova I, Kubera M, Ringel K.

Prog Neuropsychopharmacol Biol Psychiatry. 2012 Jan 10;36(1):169-75. doi: 10.1016/j.pnpbp.2011.09.006. Epub 2011 Sep 16.

PMID:
21945535
20.

Increased 8-hydroxy-deoxyguanosine, a marker of oxidative damage to DNA, in major depression and myalgic encephalomyelitis / chronic fatigue syndrome.

Maes M, Mihaylova I, Kubera M, Uytterhoeven M, Vrydags N, Bosmans E.

Neuro Endocrinol Lett. 2009;30(6):715-22.

PMID:
20035260

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