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Items: 1 to 20 of 103

1.

Impaired neurosteroid synthesis in multiple sclerosis.

Noorbakhsh F, Ellestad KK, Maingat F, Warren KG, Han MH, Steinman L, Baker GB, Power C.

Brain. 2011 Sep;134(Pt 9):2703-21. doi: 10.1093/brain/awr200.

2.

GABA transport and neuroinflammation are coupled in multiple sclerosis: regulation of the GABA transporter-2 by ganaxolone.

Paul AM, Branton WG, Walsh JG, Polyak MJ, Lu JQ, Baker GB, Power C.

Neuroscience. 2014 Jul 25;273:24-38. doi: 10.1016/j.neuroscience.2014.04.037. Epub 2014 May 9.

PMID:
24814730
3.

Suppressed oligodendrocyte steroidogenesis in multiple sclerosis: Implications for regulation of neuroinflammation.

Boghozian R, McKenzie BA, Saito LB, Mehta N, Branton WG, Lu J, Baker GB, Noorbakhsh F, Power C.

Glia. 2017 Oct;65(10):1590-1606. doi: 10.1002/glia.23179. Epub 2017 Jul 14.

PMID:
28707358
4.

Progesterone treatment modulates mRNA OF neurosteroidogenic enzymes in a murine model of multiple sclerosis.

Garay L, Gonzalez Giqueaux P, Guennoun R, Schumacher M, Gonzalez Deniselle MC, De Nicola AF.

J Steroid Biochem Mol Biol. 2017 Jan;165(Pt B):421-429. doi: 10.1016/j.jsbmb.2016.09.001. Epub 2016 Sep 3.

PMID:
27597394
5.

MiR-30a Positively Regulates the Inflammatory Response of Microglia in Experimental Autoimmune Encephalomyelitis.

Fang X, Sun D, Wang Z, Yu Z, Liu W, Pu Y, Wang D, Huang A, Liu M, Xiang Z, He C, Cao L.

Neurosci Bull. 2017 Dec;33(6):603-615. doi: 10.1007/s12264-017-0153-y. Epub 2017 Jul 17.

PMID:
28717866
6.

Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway.

Linker RA, Lee DH, Ryan S, van Dam AM, Conrad R, Bista P, Zeng W, Hronowsky X, Buko A, Chollate S, Ellrichmann G, Brück W, Dawson K, Goelz S, Wiese S, Scannevin RH, Lukashev M, Gold R.

Brain. 2011 Mar;134(Pt 3):678-92. doi: 10.1093/brain/awq386.

PMID:
21354971
7.

Micro-RNA dysregulation in multiple sclerosis favours pro-inflammatory T-cell-mediated autoimmunity.

Guerau-de-Arellano M, Smith KM, Godlewski J, Liu Y, Winger R, Lawler SE, Whitacre CC, Racke MK, Lovett-Racke AE.

Brain. 2011 Dec;134(Pt 12):3578-89. doi: 10.1093/brain/awr262. Epub 2011 Nov 15.

8.

Re-expression of a developmentally restricted potassium channel in autoimmune demyelination: Kv1.4 is implicated in oligodendroglial proliferation.

Herrero-Herranz E, Pardo LA, Bunt G, Gold R, Stühmer W, Linker RA.

Am J Pathol. 2007 Aug;171(2):589-98. Epub 2007 Jun 28.

9.

Limiting multiple sclerosis related axonopathy by blocking Nogo receptor and CRMP-2 phosphorylation.

Petratos S, Ozturk E, Azari MF, Kenny R, Lee JY, Magee KA, Harvey AR, McDonald C, Taghian K, Moussa L, Mun Aui P, Siatskas C, Litwak S, Fehlings MG, Strittmatter SM, Bernard CC.

Brain. 2012 Jun;135(Pt 6):1794-818. doi: 10.1093/brain/aws100. Epub 2012 Apr 28.

10.

Safinamide and flecainide protect axons and reduce microglial activation in models of multiple sclerosis.

Morsali D, Bechtold D, Lee W, Chauhdry S, Palchaudhuri U, Hassoon P, Snell DM, Malpass K, Piers T, Pocock J, Roach A, Smith KJ.

Brain. 2013 Apr;136(Pt 4):1067-82. doi: 10.1093/brain/awt041. Epub 2013 Mar 20.

PMID:
23518709
11.

Proteinase-activated receptor 2 modulates neuroinflammation in experimental autoimmune encephalomyelitis and multiple sclerosis.

Noorbakhsh F, Tsutsui S, Vergnolle N, Boven LA, Shariat N, Vodjgani M, Warren KG, Andrade-Gordon P, Hollenberg MD, Power C.

J Exp Med. 2006 Feb 20;203(2):425-35. Epub 2006 Feb 13.

12.

miR-155-3p Drives the Development of Autoimmune Demyelination by Regulation of Heat Shock Protein 40.

Mycko MP, Cichalewska M, Cwiklinska H, Selmaj KW.

J Neurosci. 2015 Dec 16;35(50):16504-15. doi: 10.1523/JNEUROSCI.2830-15.2015.

13.

MicroRNA-155 modulates Th1 and Th17 cell differentiation and is associated with multiple sclerosis and experimental autoimmune encephalomyelitis.

Zhang J, Cheng Y, Cui W, Li M, Li B, Guo L.

J Neuroimmunol. 2014 Jan 15;266(1-2):56-63. doi: 10.1016/j.jneuroim.2013.09.019. Epub 2013 Oct 8.

PMID:
24332164
14.

Regulation of gene expression in experimental autoimmune encephalomyelitis indicates early neuronal dysfunction.

Nicot A, Ratnakar PV, Ron Y, Chen CC, Elkabes S.

Brain. 2003 Feb;126(Pt 2):398-412.

PMID:
12538406
15.

Triterpenoid modulation of IL-17 and Nrf-2 expression ameliorates neuroinflammation and promotes remyelination in autoimmune encephalomyelitis.

Pareek TK, Belkadi A, Kesavapany S, Zaremba A, Loh SL, Bai L, Cohen ML, Meyer C, Liby KT, Miller RH, Sporn MB, Letterio JJ.

Sci Rep. 2011;1:201. doi: 10.1038/srep00201. Epub 2011 Dec 19.

16.

Discovery of novel disease-specific and membrane-associated candidate markers in a mouse model of multiple sclerosis.

Dagley LF, Croft NP, Isserlin R, Olsen JB, Fong V, Emili A, Purcell AW.

Mol Cell Proteomics. 2014 Mar;13(3):679-700. doi: 10.1074/mcp.M113.033340. Epub 2013 Dec 20.

17.

Pattern of axonal injury in murine myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis: implications for multiple sclerosis.

Herrero-Herranz E, Pardo LA, Gold R, Linker RA.

Neurobiol Dis. 2008 May;30(2):162-73. doi: 10.1016/j.nbd.2008.01.001. Epub 2008 Jan 26.

PMID:
18342527
18.

Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitis.

Kleiter I, Song J, Lukas D, Hasan M, Neumann B, Croxford AL, Pedré X, Hövelmeyer N, Yogev N, Mildner A, Prinz M, Wiese E, Reifenberg K, Bittner S, Wiendl H, Steinman L, Becker C, Bogdahn U, Neurath MF, Steinbrecher A, Waisman A.

Brain. 2010 Apr;133(Pt 4):1067-81. doi: 10.1093/brain/awq039. Epub 2010 Mar 30.

19.

Differential efficacy of the TSPO ligands etifoxine and XBD-173 in two rodent models of Multiple Sclerosis.

Ravikumar B, Crawford D, Dellovade T, Savinainen A, Graham D, Liere P, Oudinet JP, Webb M, Hering H.

Neuropharmacology. 2016 Sep;108:229-37. doi: 10.1016/j.neuropharm.2016.03.053. Epub 2016 Mar 30.

PMID:
27039042
20.

miR-17-92 cluster targets phosphatase and tensin homology and Ikaros Family Zinc Finger 4 to promote TH17-mediated inflammation.

Liu SQ, Jiang S, Li C, Zhang B, Li QJ.

J Biol Chem. 2014 May 2;289(18):12446-56. doi: 10.1074/jbc.M114.550723. Epub 2014 Mar 18.

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