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Impaired B cell development and function in the absence of IkappaBNS.

Touma M, Keskin DB, Shiroki F, Saito I, Koyasu S, Reinherz EL, Clayton LK.

J Immunol. 2011 Oct 15;187(8):3942-52. doi: 10.4049/jimmunol.1002109. Epub 2011 Sep 7.


Caspase 6 regulates B cell activation and differentiation into plasma cells.

Watanabe C, Shu GL, Zheng TS, Flavell RA, Clark EA.

J Immunol. 2008 Nov 15;181(10):6810-9.


Anti-CD180 (RP105) activates B cells to rapidly produce polyclonal Ig via a T cell and MyD88-independent pathway.

Chaplin JW, Kasahara S, Clark EA, Ledbetter JA.

J Immunol. 2011 Oct 15;187(8):4199-209. doi: 10.4049/jimmunol.1100198. Epub 2011 Sep 14.


IκBNS regulates murine Th17 differentiation during gut inflammation and infection.

Annemann M, Wang Z, Plaza-Sirvent C, Glauben R, Schuster M, Ewald Sander F, Mamareli P, Kühl AA, Siegmund B, Lochner M, Schmitz I.

J Immunol. 2015 Mar 15;194(6):2888-98. doi: 10.4049/jimmunol.1401964. Epub 2015 Feb 18.


The nuclear IkappaB protein IkappaBNS selectively inhibits lipopolysaccharide-induced IL-6 production in macrophages of the colonic lamina propria.

Hirotani T, Lee PY, Kuwata H, Yamamoto M, Matsumoto M, Kawase I, Akira S, Takeda K.

J Immunol. 2005 Mar 15;174(6):3650-7.


B-1a transitional cells are phenotypically distinct and are lacking in mice deficient in IκBNS.

Pedersen GK, Àdori M, Khoenkhoen S, Dosenovic P, Beutler B, Karlsson Hedestam GB.

Proc Natl Acad Sci U S A. 2014 Sep 30;111(39):E4119-26. doi: 10.1073/pnas.1415866111. Epub 2014 Sep 16.


The atypical IκB protein IκB(NS) is important for Toll-like receptor-induced interleukin-10 production in B cells.

Miura M, Hasegawa N, Noguchi M, Sugimoto K, Touma M.

Immunology. 2016 Apr;147(4):453-63. doi: 10.1111/imm.12578. Epub 2016 Feb 8.


The RP105/MD-1 complex is indispensable for TLR4/MD-2-dependent proliferation and IgM-secreting plasma cell differentiation of marginal zone B cells.

Nagai Y, Yanagibashi T, Watanabe Y, Ikutani M, Kariyone A, Ohta S, Hirai Y, Kimoto M, Miyake K, Takatsu K.

Int Immunol. 2012 Jun;24(6):389-400. doi: 10.1093/intimm/dxs040. Epub 2012 Feb 21.


B cell autophagy mediates TLR7-dependent autoimmunity and inflammation.

Weindel CG, Richey LJ, Bolland S, Mehta AJ, Kearney JF, Huber BT.

Autophagy. 2015;11(7):1010-24. doi: 10.1080/15548627.2015.1052206.


CD38 cross-linking enhances TLR-induced B cell proliferation but decreases IgM plasma cell differentiation.

Manjarrez-Orduño N, Moreno-García ME, Fink K, Santos-Argumedo L.

Eur J Immunol. 2007 Feb;37(2):358-67.


Constitutive CD40 Signaling Calibrates Differentiation Outcomes in Responding B Cells via Multiple Molecular Pathways.

Basu S, Kaw S, D'Souza L, Vaidya T, Bal V, Rath S, George A.

J Immunol. 2016 Aug 1;197(3):761-70. doi: 10.4049/jimmunol.1600077. Epub 2016 Jun 24.


Heterozygous Mutation in IκBNS Leads to Reduced Levels of Natural IgM Antibodies and Impaired Responses to T-Independent Type 2 Antigens.

Pedersen GK, Ádori M, Stark JM, Khoenkhoen S, Arnold C, Beutler B, Karlsson Hedestam GB.

Front Immunol. 2016 Mar 1;7:65. doi: 10.3389/fimmu.2016.00065. eCollection 2016.


Themis2 is not required for B cell development, activation, and antibody responses.

Hartweger H, Schweighoffer E, Davidson S, Peirce MJ, Wack A, Tybulewicz VL.

J Immunol. 2014 Jul 15;193(2):700-7. doi: 10.4049/jimmunol.1400943. Epub 2014 Jun 6.


Hemokinin-1 activates the MAPK pathway and enhances B cell proliferation and antibody production.

Wang W, Li Q, Zhang J, Wu H, Yin Y, Ge Q, Zhang Y.

J Immunol. 2010 Apr 1;184(7):3590-7. doi: 10.4049/jimmunol.0901278. Epub 2010 Mar 5.


Signaling through CD70 regulates B cell activation and IgG production.

Arens R, Nolte MA, Tesselaar K, Heemskerk B, Reedquist KA, van Lier RA, van Oers MH.

J Immunol. 2004 Sep 15;173(6):3901-8.


B cell-specific expression of B7-2 is required for follicular Th cell function in response to vaccinia virus.

Salek-Ardakani S, Choi YS, Rafii-El-Idrissi Benhnia M, Flynn R, Arens R, Shoenberger S, Crotty S, Croft M, Salek-Ardakani S.

J Immunol. 2011 May 1;186(9):5294-303. doi: 10.4049/jimmunol.1100406. Epub 2011 Mar 25.


IL-17A Promotes Pulmonary B-1a Cell Differentiation via Induction of Blimp-1 Expression during Influenza Virus Infection.

Wang X, Ma K, Chen M, Ko KH, Zheng BJ, Lu L.

PLoS Pathog. 2016 Jan 6;12(1):e1005367. doi: 10.1371/journal.ppat.1005367. eCollection 2016 Jan.


CD4+ Th2 cells function alike effector Tr1 and Th1 cells through the deletion of a single cytokine IL-6 and IL-10 gene.

Ankathatti Munegowda M, Xu S, Freywald A, Xiang J.

Mol Immunol. 2012 Jun;51(2):143-9. doi: 10.1016/j.molimm.2012.02.120. Epub 2012 Mar 17.


Retinal self-antigen induces a predominantly Th1 effector response in Axl and Mertk double-knockout mice.

Ye F, Han L, Lu Q, Dong W, Chen Z, Shao H, Kaplan HJ, Li Q, Lu Q.

J Immunol. 2011 Oct 15;187(8):4178-86. doi: 10.4049/jimmunol.1101201. Epub 2011 Sep 14.

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