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Items: 1 to 20 of 106

1.

Cannabinoid receptor type I modulates alcohol-induced liver fibrosis.

Patsenker E, Stoll M, Millonig G, Agaimy A, Wissniowski T, Schneider V, Mueller S, Brenneisen R, Seitz HK, Ocker M, Stickel F.

Mol Med. 2011;17(11-12):1285-94. doi: 10.2119/molmed.2011.00149. Epub 2011 Aug 19.

2.

Role of cannabinoid receptors in alcoholic hepatic injury: steatosis and fibrogenesis are increased in CB2 receptor-deficient mice and decreased in CB1 receptor knockouts.

Trebicka J, Racz I, Siegmund SV, Cara E, Granzow M, Schierwagen R, Klein S, Wojtalla A, Hennenberg M, Huss S, Fischer HP, Heller J, Zimmer A, Sauerbruch T.

Liver Int. 2011 Jul;31(6):860-70. doi: 10.1111/j.1478-3231.2011.02496.x. Epub 2011 Mar 8.

PMID:
21645218
3.

Rimonabant inhibits proliferation, collagen secretion and induces apoptosis in hepatic stellate cells.

Dai E, Zhang J, Zhang D, Yang L, Wang Y, Jiang X, Ye L, Li X, Liu H, Ma J, Jiang H.

Hepatogastroenterology. 2014 Oct;61(135):2052-61.

PMID:
25713910
4.

CB1 cannabinoid receptor antagonism: a new strategy for the treatment of liver fibrosis.

Teixeira-Clerc F, Julien B, Grenard P, Tran Van Nhieu J, Deveaux V, Li L, Serriere-Lanneau V, Ledent C, Mallat A, Lotersztajn S.

Nat Med. 2006 Jun;12(6):671-6. Epub 2006 May 21.

PMID:
16715087
5.

Osteopontin is an important mediator of alcoholic liver disease via hepatic stellate cell activation.

Seth D, Duly A, Kuo PC, McCaughan GW, Haber PS.

World J Gastroenterol. 2014 Sep 28;20(36):13088-104. doi: 10.3748/wjg.v20.i36.13088.

6.

Reversal of liver fibrosis by the antagonism of endocannabinoid CB1 receptor in a rat model of CCl(4)-induced advanced cirrhosis.

Giannone FA, Baldassarre M, Domenicali M, Zaccherini G, Trevisani F, Bernardi M, Caraceni P.

Lab Invest. 2012 Mar;92(3):384-95. doi: 10.1038/labinvest.2011.191. Epub 2011 Dec 19.

7.

Role of cannabinoid receptors in hepatic fibrosis and apoptosis associated with bile duct ligation in rats.

Mahmoud MF, Swefy SE, Hasan RA, Ibrahim A.

Eur J Pharmacol. 2014 Nov 5;742:118-24. doi: 10.1016/j.ejphar.2014.08.021. Epub 2014 Aug 30.

PMID:
25179573
8.

Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver.

Jeong WI, Osei-Hyiaman D, Park O, Liu J, Bátkai S, Mukhopadhyay P, Horiguchi N, Harvey-White J, Marsicano G, Lutz B, Gao B, Kunos G.

Cell Metab. 2008 Mar;7(3):227-35. doi: 10.1016/j.cmet.2007.12.007.

9.

Anandamide induces cell death through lipid rafts in hepatic stellate cells.

Yang Q, Liu HY, Zhang YW, Wu WJ, Tang WX.

J Gastroenterol Hepatol. 2010 May;25(5):991-1001. doi: 10.1111/j.1440-1746.2009.06122.x. Epub 2010 Jan 4.

PMID:
20059638
10.

Upregulation of cannabinoid receptor-1 and fibrotic activation of mouse hepatic stellate cells during Schistosoma J. infection: role of NADPH oxidase.

Wang M, Abais JM, Meng N, Zhang Y, Ritter JK, Li PL, Tang WX.

Free Radic Biol Med. 2014 Jun;71:109-20. doi: 10.1016/j.freeradbiomed.2014.03.015. Epub 2014 Mar 19.

PMID:
24657416
11.

EPAC activation inhibits acetaldehyde-induced activation and proliferation of hepatic stellate cell via Rap1.

Yang Y, Yang F, Wu X, Lv X, Li J.

Can J Physiol Pharmacol. 2016 May;94(5):498-507. doi: 10.1139/cjpp-2015-0437. Epub 2015 Nov 19.

PMID:
26854595
12.

Suppression of CB1 cannabinoid receptor by lentivirus mediated small interfering RNA ameliorates hepatic fibrosis in rats.

Chen SW, Wu BY, Xu SP, Fan KX, Yan L, Gong Y, Wen JB, Wu DH.

PLoS One. 2012;7(12):e50850. doi: 10.1371/journal.pone.0050850. Epub 2012 Dec 12.

13.

Cannabinoid receptor 1 is a major mediator of renal fibrosis.

Lecru L, Desterke C, Grassin-Delyle S, Chatziantoniou C, Vandermeersch S, Devocelle A, Vernochet A, Ivanovski N, Ledent C, Ferlicot S, Dalia M, Saïd M, Beaudreuil S, Charpentier B, Vazquez A, Giron-Michel J, Azzarone B, Durrbach A, François H.

Kidney Int. 2015 Jul;88(1):72-84. doi: 10.1038/ki.2015.63. Epub 2015 Mar 11.

PMID:
25760323
14.

Bcl-2 overexpression in hepatic stellate cell line CFSC-2G, induces a pro-fibrotic state.

González-Puertos VY, Hernández-Pérez E, Nuño-Lámbarri N, Ventura-Gallegos JL, López-Diázguerrero NE, Robles-Díaz G, Gutiérrez-Ruiz MC, Konigsberg M.

J Gastroenterol Hepatol. 2010 Jul;25(7):1306-14. doi: 10.1111/j.1440-1746.2009.06175.x.

PMID:
20594261
15.

Role of cannabinoids in chronic liver diseases.

Parfieniuk A, Flisiak R.

World J Gastroenterol. 2008 Oct 28;14(40):6109-14. Review.

16.

FXR agonist obeticholic acid reduces hepatic inflammation and fibrosis in a rat model of toxic cirrhosis.

Verbeke L, Mannaerts I, Schierwagen R, Govaere O, Klein S, Vander Elst I, Windmolders P, Farre R, Wenes M, Mazzone M, Nevens F, van Grunsven LA, Trebicka J, Laleman W.

Sci Rep. 2016 Sep 16;6:33453. doi: 10.1038/srep33453.

17.

Hepatic expression of cannabinoid receptors CB1 and CB2 correlate with fibrogenesis in patients with chronic hepatitis B.

Dai E, Zhang L, Ye L, Wan S, Feng L, Qi Q, Yao F, Li Z.

Int J Infect Dis. 2017 Jun;59:124-130. doi: 10.1016/j.ijid.2017.03.008. Epub 2017 Mar 15.

18.

Effect of indole-3-carbinol on ethanol-induced liver injury and acetaldehyde-stimulated hepatic stellate cells activation using precision-cut rat liver slices.

Guo Y, Wu XQ, Zhang C, Liao ZX, Wu Y, Xia ZY, Wang H.

Clin Exp Pharmacol Physiol. 2010 Dec;37(12):1107-13. doi: 10.1111/j.1440-1681.2010.05450.x.

PMID:
20880187
19.

The direct profibrotic and indirect immune antifibrotic balance of blocking the cannabinoid 2 receptor.

Avraham Y, Amer J, Doron S, Abu-Tair L, Mahamid M, Khatib A, Berry EM, Safadi R.

Am J Physiol Gastrointest Liver Physiol. 2012 Jun 15;302(12):G1364-72. doi: 10.1152/ajpgi.00191.2011. Epub 2012 Apr 19.

20.

Caffeine protects against alcohol-induced liver fibrosis by dampening the cAMP/PKA/CREB pathway in rat hepatic stellate cells.

Wang Q, Dai X, Yang W, Wang H, Zhao H, Yang F, Yang Y, Li J, Lv X.

Int Immunopharmacol. 2015 Apr;25(2):340-52. doi: 10.1016/j.intimp.2015.02.012. Epub 2015 Feb 18.

PMID:
25701503

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