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Items: 1 to 20 of 90

1.

The hydroxylase inhibitor dimethyloxallyl glycine attenuates endotoxic shock via alternative activation of macrophages and IL-10 production by B1 cells.

Hams E, Saunders SP, Cummins EP, O'Connor A, Tambuwala MT, Gallagher WM, Byrne A, Campos-Torres A, Moynagh PM, Jobin C, Taylor CT, Fallon PG.

Shock. 2011 Sep;36(3):295-302. doi: 10.1097/SHK.0b013e318225ad7e.

2.

Inhibition of prolyl hydroxylase domain-containing protein suppressed lipopolysaccharide-induced TNF-alpha expression.

Takeda K, Ichiki T, Narabayashi E, Inanaga K, Miyazaki R, Hashimoto T, Matsuura H, Ikeda J, Miyata T, Sunagawa K.

Arterioscler Thromb Vasc Biol. 2009 Dec;29(12):2132-7. doi: 10.1161/ATVBAHA.109.196071. Epub 2009 Sep 17.

PMID:
19762779
4.

The hydroxylase inhibitor dimethyloxalylglycine is protective in a murine model of colitis.

Cummins EP, Seeballuck F, Keely SJ, Mangan NE, Callanan JJ, Fallon PG, Taylor CT.

Gastroenterology. 2008 Jan;134(1):156-65. doi: 10.1053/j.gastro.2007.10.012. Epub 2007 Oct 10.

PMID:
18166353
5.

Targeted delivery of the hydroxylase inhibitor DMOG provides enhanced efficacy with reduced systemic exposure in a murine model of colitis.

Tambuwala MM, Manresa MC, Cummins EP, Aversa V, Coulter IS, Taylor CT.

J Control Release. 2015 Nov 10;217:221-7. doi: 10.1016/j.jconrel.2015.09.022. Epub 2015 Sep 16.

PMID:
26385165
6.

PC-SPES: a potent inhibitor of nuclear factor-kappa B rescues mice from lipopolysaccharide-induced septic shock.

Ikezoe T, Yang Y, Heber D, Taguchi H, Koeffler HP.

Mol Pharmacol. 2003 Dec;64(6):1521-9.

7.

Deferoxamine attenuates lipopolysaccharide-induced inflammatory responses and protects against endotoxic shock in mice.

Wang S, Liu C, Pan S, Miao Q, Xue J, Xun J, Zhang Y, Gao Y, Duan X, Fan Y.

Biochem Biophys Res Commun. 2015 Sep 18;465(2):305-11. doi: 10.1016/j.bbrc.2015.08.032. Epub 2015 Aug 13.

PMID:
26277391
8.

In vitro and in vivo therapeutics of β-thujaplicin on LPS-induced inflammation in macrophages and septic shock in mice.

Shih MF, Chen LY, Tsai PJ, Cherng JY.

Int J Immunopathol Pharmacol. 2012 Jan-Mar;25(1):39-48.

PMID:
22507316
9.

Dietary histidine ameliorates murine colitis by inhibition of proinflammatory cytokine production from macrophages.

Andou A, Hisamatsu T, Okamoto S, Chinen H, Kamada N, Kobayashi T, Hashimoto M, Okutsu T, Shimbo K, Takeda T, Matsumoto H, Sato A, Ohtsu H, Suzuki M, Hibi T.

Gastroenterology. 2009 Feb;136(2):564-74.e2. doi: 10.1053/j.gastro.2008.09.062. Epub 2008 Oct 7.

PMID:
19027739
10.

Enalapril inhibits nuclear factor-κB signaling in intestinal epithelial cells and peritoneal macrophages and attenuates experimental colitis in mice.

Lee C, Chun J, Hwang SW, Kang SJ, Im JP, Kim JS.

Life Sci. 2014 Jan 24;95(1):29-39. doi: 10.1016/j.lfs.2013.11.005. Epub 2013 Nov 15.

PMID:
24239644
11.

Anti-inflammatory effects of benzenediamine derivate FC-98 on sepsis injury in mice via suppression of JNK, NF-κB and IRF3 signaling pathways.

Song Y, Liu X, Yue H, Ji J, Dou H, Hou Y.

Mol Immunol. 2015 Oct;67(2 Pt B):183-92. doi: 10.1016/j.molimm.2015.05.005. Epub 2015 May 29.

PMID:
26032013
12.

Hydroxylase inhibition abrogates TNF-alpha-induced intestinal epithelial damage by hypoxia-inducible factor-1-dependent repression of FADD.

Hindryckx P, De Vos M, Jacques P, Ferdinande L, Peeters H, Olievier K, Bogaert S, Brinkman B, Vandenabeele P, Elewaut D, Laukens D.

J Immunol. 2010 Nov 15;185(10):6306-16. doi: 10.4049/jimmunol.1002541. Epub 2010 Oct 13.

13.

5,6,7-trimethoxyflavone suppresses pro-inflammatory mediators in lipopolysaccharide-induced RAW 264.7 macrophages and protects mice from lethal endotoxin shock.

Rim HK, Yun CH, Shin JS, Cho YW, Jang DS, Ryu JH, Park H, Lee KT.

Food Chem Toxicol. 2013 Dec;62:847-55. doi: 10.1016/j.fct.2013.10.025. Epub 2013 Oct 24.

PMID:
24161485
14.

Inhibition of nitric oxide and inflammatory cytokines in LPS-stimulated murine macrophages by resveratrol, a potent proteasome inhibitor.

Qureshi AA, Guan XQ, Reis JC, Papasian CJ, Jabre S, Morrison DC, Qureshi N.

Lipids Health Dis. 2012 Jul 10;11:76. doi: 10.1186/1476-511X-11-76.

15.

Anti-inflammatory effect of a Nuphar lutea partially purified leaf extract in murine models of septic shock.

Ozer J, Levi T, Golan-Goldhirsh A, Gopas J.

J Ethnopharmacol. 2015 Feb 23;161:86-91. doi: 10.1016/j.jep.2014.11.048. Epub 2014 Dec 6.

PMID:
25490314
16.

Protective Effects of Nobiletin Against Endotoxic Shock in Mice Through Inhibiting TNF-α, IL-6, and HMGB1 and Regulating NF-κB Pathway.

Li W, Wang X, Niu X, Zhang H, He Z, Wang Y, Zhi W, Liu F.

Inflammation. 2016 Apr;39(2):786-97. doi: 10.1007/s10753-016-0307-5.

PMID:
26846885
17.

Arvelexin from Brassica rapa suppresses NF-κB-regulated pro-inflammatory gene expression by inhibiting activation of IκB kinase.

Shin JS, Noh YS, Lee YS, Cho YW, Baek NI, Choi MS, Jeong TS, Kang E, Chung HG, Lee KT.

Br J Pharmacol. 2011 Sep;164(1):145-58. doi: 10.1111/j.1476-5381.2011.01351.x.

18.

Anticancer agent 2-methoxyestradiol improves survival in septic mice by reducing the production of cytokines and nitric oxide.

Yeh CH, Chou W, Chu CC, So EC, Chang HC, Wang JJ, Hsing CH.

Shock. 2011 Nov;36(5):510-6. doi: 10.1097/SHK.0b013e318231866f. Erratum in: Shock. 2011 Dec;36(6):635.

PMID:
21841536
19.

Ursolic acid inhibits nuclear factor-κB signaling in intestinal epithelial cells and macrophages, and attenuates experimental colitis in mice.

Chun J, Lee C, Hwang SW, Im JP, Kim JS.

Life Sci. 2014 Aug 6;110(1):23-34. doi: 10.1016/j.lfs.2014.06.018. Epub 2014 Jun 30.

PMID:
24992474
20.

Tim-4 protects mice against lipopolysaccharide-induced endotoxic shock by suppressing the NF-κB signaling pathway.

Xu L, Zhao P, Xu Y, Gao L, Wang H, Jia X, Ma H, Liang X, Ma C, Gao L.

Lab Invest. 2016 Nov;96(11):1189-1197. doi: 10.1038/labinvest.2016.94. Epub 2016 Sep 12.

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