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Items: 1 to 20 of 86

1.

Rab5 and class III phosphoinositide 3-kinase Vps34 are involved in hepatitis C virus NS4B-induced autophagy.

Su WC, Chao TC, Huang YL, Weng SC, Jeng KS, Lai MM.

J Virol. 2011 Oct;85(20):10561-71. doi: 10.1128/JVI.00173-11. Epub 2011 Aug 10.

2.

Ehrlichia secretes Etf-1 to induce autophagy and capture nutrients for its growth through RAB5 and class III phosphatidylinositol 3-kinase.

Lin M, Liu H, Xiong Q, Niu H, Cheng Z, Yamamoto A, Rikihisa Y.

Autophagy. 2016 Nov;12(11):2145-2166. Epub 2016 Aug 19.

3.

Formation and function of hepatitis C virus replication complexes require residues in the carboxy-terminal domain of NS4B protein.

Aligo J, Jia S, Manna D, Konan KV.

Virology. 2009 Oct 10;393(1):68-83. doi: 10.1016/j.virol.2009.07.033. Epub 2009 Aug 22.

4.

Participation of rab5, an early endosome protein, in hepatitis C virus RNA replication machinery.

Stone M, Jia S, Heo WD, Meyer T, Konan KV.

J Virol. 2007 May;81(9):4551-63. Epub 2007 Feb 14.

5.

Hepatitis C virus NS4B blocks the interaction of STING and TBK1 to evade host innate immunity.

Ding Q, Cao X, Lu J, Huang B, Liu YJ, Kato N, Shu HB, Zhong J.

J Hepatol. 2013 Jul;59(1):52-8. doi: 10.1016/j.jhep.2013.03.019. Epub 2013 Mar 28.

PMID:
23542348
6.

Prolactin Regulatory Element Binding Protein Is Involved in Hepatitis C Virus Replication by Interaction with NS4B.

Kong L, Fujimoto A, Nakamura M, Aoyagi H, Matsuda M, Watashi K, Suzuki R, Arita M, Yamagoe S, Dohmae N, Suzuki T, Sakamaki Y, Ichinose S, Suzuki T, Wakita T, Aizaki H.

J Virol. 2016 Jan 6;90(6):3093-111. doi: 10.1128/JVI.01540-15.

7.

Interaction networks of hepatitis C virus NS4B: implications for antiviral therapy.

Li S, Yu X, Guo Y, Kong L.

Cell Microbiol. 2012 Jul;14(7):994-1002. doi: 10.1111/j.1462-5822.2012.01773.x. Epub 2012 Mar 5. Review.

PMID:
22329740
8.

HCV NS4B induces apoptosis through the mitochondrial death pathway.

Zhao P, Han T, Guo JJ, Zhu SL, Wang J, Ao F, Jing MZ, She YL, Wu ZH, Ye LB.

Virus Res. 2012 Oct;169(1):1-7. doi: 10.1016/j.virusres.2012.04.006. Epub 2012 Apr 19.

PMID:
22542667
9.

PKD is a kinase of Vps34 that mediates ROS-induced autophagy downstream of DAPk.

Eisenberg-Lerner A, Kimchi A.

Cell Death Differ. 2012 May;19(5):788-97. doi: 10.1038/cdd.2011.149. Epub 2011 Nov 18.

10.

NS4B self-interaction through conserved C-terminal elements is required for the establishment of functional hepatitis C virus replication complexes.

Paul D, Romero-Brey I, Gouttenoire J, Stoitsova S, Krijnse-Locker J, Moradpour D, Bartenschlager R.

J Virol. 2011 Jul;85(14):6963-76. doi: 10.1128/JVI.00502-11. Epub 2011 May 4.

11.

Network based analysis of hepatitis C virus core and NS4B protein interactions.

Tripathi LP, Kataoka C, Taguwa S, Moriishi K, Mori Y, Matsuura Y, Mizuguchi K.

Mol Biosyst. 2010 Dec;6(12):2539-53. doi: 10.1039/c0mb00103a. Epub 2010 Oct 18.

PMID:
20953506
12.

Hepatitis C virus NS4B carboxy terminal domain is a membrane binding domain.

Liefhebber JM, Brandt BW, Broer R, Spaan WJ, van Leeuwen HC.

Virol J. 2009 May 25;6:62. doi: 10.1186/1743-422X-6-62.

13.

Hepatitis C virus upregulates Beclin1 for induction of autophagy and activates mTOR signaling.

Shrivastava S, Bhanja Chowdhury J, Steele R, Ray R, Ray RB.

J Virol. 2012 Aug;86(16):8705-12. doi: 10.1128/JVI.00616-12. Epub 2012 Jun 6.

14.

Endocytic Rab proteins are required for hepatitis C virus replication complex formation.

Manna D, Aligo J, Xu C, Park WS, Koc H, Heo WD, Konan KV.

Virology. 2010 Mar 1;398(1):21-37. doi: 10.1016/j.virol.2009.11.034. Epub 2009 Dec 16.

15.

The hepatitis C virus nonstructural protein 4B is an integral endoplasmic reticulum membrane protein.

Hügle T, Fehrmann F, Bieck E, Kohara M, Kräusslich HG, Rice CM, Blum HE, Moradpour D.

Virology. 2001 May 25;284(1):70-81.

16.

Biochemical characterization of recombinant hepatitis C virus nonstructural protein 4B: evidence for ATP/GTP hydrolysis and adenylate kinase activity.

Thompson AA, Zou A, Yan J, Duggal R, Hao W, Molina D, Cronin CN, Wells PA.

Biochemistry. 2009 Feb 10;48(5):906-16. doi: 10.1021/bi801747p.

PMID:
19146391
17.

Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex.

McKnight NC, Zhong Y, Wold MS, Gong S, Phillips GR, Dou Z, Zhao Y, Heintz N, Zong WX, Yue Z.

PLoS Genet. 2014 Oct 2;10(10):e1004626. doi: 10.1371/journal.pgen.1004626. eCollection 2014 Oct.

18.

Reticulon 3 interacts with NS4B of the hepatitis C virus and negatively regulates viral replication by disrupting NS4B self-interaction.

Wu MJ, Ke PY, Hsu JT, Yeh CT, Horng JT.

Cell Microbiol. 2014 Nov;16(11):1603-18. doi: 10.1111/cmi.12318. Epub 2014 Jul 7.

PMID:
24898729
19.

Polo-like kinase 1 is involved in hepatitis C virus replication by hyperphosphorylating NS5A.

Chen YC, Su WC, Huang JY, Chao TC, Jeng KS, Machida K, Lai MM.

J Virol. 2010 Aug;84(16):7983-93. doi: 10.1128/JVI.00068-10. Epub 2010 Jun 9.

20.

Class IA PI3K p110β subunit promotes autophagy through Rab5 small GTPase in response to growth factor limitation.

Dou Z, Pan JA, Dbouk HA, Ballou LM, DeLeon JL, Fan Y, Chen JS, Liang Z, Li G, Backer JM, Lin RZ, Zong WX.

Mol Cell. 2013 Apr 11;50(1):29-42. doi: 10.1016/j.molcel.2013.01.022. Epub 2013 Feb 21.

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