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Items: 1 to 20 of 467

1.

DDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signaling.

Miyashita M, Oshiumi H, Matsumoto M, Seya T.

Mol Cell Biol. 2011 Sep;31(18):3802-19. doi: 10.1128/MCB.01368-10. Epub 2011 Jul 26.

2.

DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-beta-inducing potential.

Oshiumi H, Sakai K, Matsumoto M, Seya T.

Eur J Immunol. 2010 Apr;40(4):940-8. doi: 10.1002/eji.200940203.

3.

DDX60 Is Involved in RIG-I-Dependent and Independent Antiviral Responses, and Its Function Is Attenuated by Virus-Induced EGFR Activation.

Oshiumi H, Miyashita M, Okamoto M, Morioka Y, Okabe M, Matsumoto M, Seya T.

Cell Rep. 2015 May 26;11(8):1193-207. doi: 10.1016/j.celrep.2015.04.047. Epub 2015 May 14.

4.

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction.

Kawai T, Takahashi K, Sato S, Coban C, Kumar H, Kato H, Ishii KJ, Takeuchi O, Akira S.

Nat Immunol. 2005 Oct;6(10):981-8. Epub 2005 Aug 28.

PMID:
16127453
5.

Evolution of the DEAD box helicase family in chicken: chickens have no DHX9 ortholog.

Sato H, Oshiumi H, Takaki H, Hikono H, Seya T.

Microbiol Immunol. 2015 Oct;59(10):633-40. doi: 10.1111/1348-0421.12322.

6.

LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses.

Satoh T, Kato H, Kumagai Y, Yoneyama M, Sato S, Matsushita K, Tsujimura T, Fujita T, Akira S, Takeuchi O.

Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1512-7. doi: 10.1073/pnas.0912986107. Epub 2010 Jan 8.

7.

SerpinB9 expression in human renal tubular epithelial cells is induced by triggering of the viral dsRNA sensors TLR3, MDA5 and RIG-I.

Heutinck KM, Kassies J, Florquin S, ten Berge IJ, Hamann J, Rowshani AT.

Nephrol Dial Transplant. 2012 Jul;27(7):2746-54. doi: 10.1093/ndt/gfr690. Epub 2011 Dec 13.

PMID:
22167597
8.

Loss of DExD/H box RNA helicase LGP2 manifests disparate antiviral responses.

Venkataraman T, Valdes M, Elsby R, Kakuta S, Caceres G, Saijo S, Iwakura Y, Barber GN.

J Immunol. 2007 May 15;178(10):6444-55.

9.

Retinoic acid-inducible gene-I-like receptors.

Onoguchi K, Yoneyama M, Fujita T.

J Interferon Cytokine Res. 2011 Jan;31(1):27-31. doi: 10.1089/jir.2010.0057. Epub 2010 Oct 15. Review.

PMID:
20950133
10.

Negative regulation of RIG-I-mediated antiviral signaling by TRK-fused gene (TFG) protein.

Lee NR, Shin HB, Kim HI, Choi MS, Inn KS.

Biochem Biophys Res Commun. 2013 Jul 19;437(1):168-72. doi: 10.1016/j.bbrc.2013.06.061. Epub 2013 Jun 26.

PMID:
23810392
11.

Identification of an LGP2-associated MDA5 agonist in picornavirus-infected cells.

Deddouche S, Goubau D, Rehwinkel J, Chakravarty P, Begum S, Maillard PV, Borg A, Matthews N, Feng Q, van Kuppeveld FJ, Reis e Sousa C.

Elife. 2014 Feb 18;3:e01535. doi: 10.7554/eLife.01535.

12.

LGP2 plays a critical role in sensitizing mda-5 to activation by double-stranded RNA.

Childs KS, Randall RE, Goodbourn S.

PLoS One. 2013 May 9;8(5):e64202. doi: 10.1371/journal.pone.0064202. Print 2013.

13.

The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA.

Pippig DA, Hellmuth JC, Cui S, Kirchhofer A, Lammens K, Lammens A, Schmidt A, Rothenfusser S, Hopfner KP.

Nucleic Acids Res. 2009 Apr;37(6):2014-25. doi: 10.1093/nar/gkp059. Epub 2009 Feb 10.

14.

Solution structures of cytosolic RNA sensor MDA5 and LGP2 C-terminal domains: identification of the RNA recognition loop in RIG-I-like receptors.

Takahasi K, Kumeta H, Tsuduki N, Narita R, Shigemoto T, Hirai R, Yoneyama M, Horiuchi M, Ogura K, Fujita T, Inagaki F.

J Biol Chem. 2009 Jun 26;284(26):17465-74. doi: 10.1074/jbc.M109.007179. Epub 2009 Apr 20.

15.

Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity.

Yoneyama M, Kikuchi M, Matsumoto K, Imaizumi T, Miyagishi M, Taira K, Foy E, Loo YM, Gale M Jr, Akira S, Yonehara S, Kato A, Fujita T.

J Immunol. 2005 Sep 1;175(5):2851-8.

16.

The Long Noncoding RNA NEAT1 Exerts Antihantaviral Effects by Acting as Positive Feedback for RIG-I Signaling.

Ma H, Han P, Ye W, Chen H, Zheng X, Cheng L, Zhang L, Yu L, Wu X, Xu Z, Lei Y, Zhang F.

J Virol. 2017 Apr 13;91(9). pii: e02250-16. doi: 10.1128/JVI.02250-16. Print 2017 May 1.

17.

Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2.

Saito T, Hirai R, Loo YM, Owen D, Johnson CL, Sinha SC, Akira S, Fujita T, Gale M Jr.

Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):582-7. Epub 2006 Dec 26.

18.

RIG-I/MDA5/MAVS are required to signal a protective IFN response in rotavirus-infected intestinal epithelium.

Broquet AH, Hirata Y, McAllister CS, Kagnoff MF.

J Immunol. 2011 Feb 1;186(3):1618-26. doi: 10.4049/jimmunol.1002862. Epub 2010 Dec 27.

19.

The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I.

Rothenfusser S, Goutagny N, DiPerna G, Gong M, Monks BG, Schoenemeyer A, Yamamoto M, Akira S, Fitzgerald KA.

J Immunol. 2005 Oct 15;175(8):5260-8.

20.

Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5B.

Kitai Y, Takeuchi O, Kawasaki T, Ori D, Sueyoshi T, Murase M, Akira S, Kawai T.

J Biol Chem. 2015 Jan 9;290(2):1269-80. doi: 10.1074/jbc.M114.611053. Epub 2014 Dec 1.

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